Dio3 | ENSRNOG00000052017 | NCBI 29475

Details for: Dio3

Gene ID: 29475

Symbol: Dio3

Ensembl ID: ENSRNOG00000052017

Description: iodothyronine deiodinase 3

Associated with

Metabolism
(R-RNO-1430728)
Metabolism of amine-derived hormones
(R-RNO-209776)
Metabolism of amino acids and derivatives
(R-RNO-71291)
Regulation of thyroid hormone activity
(R-RNO-350864)
Thyroxine biosynthesis
(R-RNO-209968)
Apoptotic process
(GO:0006915)
Brown fat cell proliferation
(GO:0070342)
Endosome membrane
(GO:0010008)
Hormone biosynthetic process
(GO:0042446)
Intracellular membrane-bounded organelle
(GO:0043231)
Plasma membrane
(GO:0005886)
Positive regulation of multicellular organism growth
(GO:0040018)
Response to hypoxia
(GO:0001666)
Retinal cone cell apoptotic process
(GO:0097474)
Retinal cone cell development
(GO:0046549)
Thyroid hormone catabolic process
(GO:0042404)
Thyroid hormone metabolic process
(GO:0042403)
Thyroxine 5'-deiodinase activity
(GO:0004800)
Thyroxine 5-deiodinase activity
(GO:0033798)

Other Information

Proteins

Thyroxine 5-deiodinase

Genular Protein ID: 79362400

Symbol: IOD3_RAT

Name: Thyroxine 5-deiodinase

UniProtKB Accession Codes:

P49897

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 7622463

Title: Cloning and expression of a cDNA for a mammalian type III iodothyronine deiodinase.

PubMed ID: 7622463

DOI: 10.1074/jbc.270.28.16569

PubMed ID: 7053997

Title: Characteristics of inner ring (3 or 5) monodeiodination of 3,5-diiodothyronine in rat liver: evidence suggesting marked similarities of inner and outer ring deiodinases for iodothyronines.

PubMed ID: 7053997

DOI: 10.1210/endo-110-1-89

Sequence Information:

Length: 304
Mass: 34096
Checksum: 899DC2E9B4104A15
Sequence:

MPRQAASRLV VGEGEGPPGA SGPAATMLRS LLLHSLRLCA QTASCLVLFP RFLGTAFMLW 
LLDFLCIRKH FLRRRHPDHP EPEVELNSEG EEMPPDDPPI CVSDDNRLCT LASLKAVWHG 
QKLDFFKQAH EGGPAPNSEV VRPDGFQSQR ILDYAQGTRP LVLNFGSCTU PPFMARMSAF 
QRLVTKYQRD VDFLIIYIEE AHPSDGWVTT DSPYVIPQHR SLEDRVSAAR VLQQGAPGCA 
LVLDTMANSS SSAYGAYFER LYVIQSGTIM YQGGRGPDGY QVSELRTWLE RYDEQLHGTR 
PRRL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.