Shh | ENSRNOG00000006120 | NCBI 29499

Details for: Shh

Gene ID: 29499

Symbol: Shh

Ensembl ID: ENSRNOG00000006120

Description: sonic hedgehog signaling molecule

Associated with

Hedgehog 'on' state
(R-RNO-5632684)
Hedgehog ligand biogenesis
(R-RNO-5358346)
Ligand-receptor interactions
(R-RNO-5632681)
Release of hh-np from the secreting cell
(R-RNO-5362798)
Signaling by hedgehog
(R-RNO-5358351)
Signal transduction
(R-RNO-162582)
Androgen metabolic process
(GO:0008209)
Angiogenesis
(GO:0001525)
Anterior/posterior pattern specification
(GO:0009952)
Axon guidance
(GO:0007411)
Blood coagulation
(GO:0007596)
Branching involved in blood vessel morphogenesis
(GO:0001569)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
Calcium ion binding
(GO:0005509)
Cell-cell signaling
(GO:0007267)
Cell fate specification
(GO:0001708)
Cell migration
(GO:0016477)
Cell population proliferation
(GO:0008283)
Cell proliferation in external granule layer
(GO:0021924)
Central nervous system development
(GO:0007417)
Cerebellar granule cell precursor proliferation
(GO:0021930)
Cholesterol-protein transferase activity
(GO:0140853)
Determination of left/right asymmetry in lateral mesoderm
(GO:0003140)
Determination of left/right symmetry
(GO:0007368)
Digestive tract mesoderm development
(GO:0007502)
Dorsal/ventral neural tube patterning
(GO:0021904)
Dorsal/ventral pattern formation
(GO:0009953)
Ectoderm development
(GO:0007398)
Embryonic limb morphogenesis
(GO:0030326)
Endocytosis
(GO:0006897)
Forebrain development
(GO:0030900)
Forebrain regionalization
(GO:0021871)
Gene expression
(GO:0010467)
Glycosaminoglycan binding
(GO:0005539)
Hair follicle development
(GO:0001942)
Heart development
(GO:0007507)
Heart looping
(GO:0001947)
Hindgut morphogenesis
(GO:0007442)
Hydrolase activity
(GO:0016787)
Intein-mediated protein splicing
(GO:0016539)
Kidney development
(GO:0001822)
Laminin-1 binding
(GO:0043237)
Lung development
(GO:0030324)
Lymphoid progenitor cell differentiation
(GO:0002320)
Male genitalia development
(GO:0030539)
Mesenchymal cell proliferation
(GO:0010463)
Metanephros development
(GO:0001656)
Midbrain development
(GO:0030901)
Myotube differentiation
(GO:0014902)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of wnt signaling pathway
(GO:0030178)
Neural crest cell migration
(GO:0001755)
Neural tube formation
(GO:0001841)
Neuroblast proliferation
(GO:0007405)
Neuron differentiation
(GO:0030182)
Oligodendrocyte development
(GO:0014003)
Osteoblast development
(GO:0002076)
Patched binding
(GO:0005113)
Pattern specification process
(GO:0007389)
Peptidase activity
(GO:0008233)
Polarity specification of anterior/posterior axis
(GO:0009949)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cerebellar granule cell precursor proliferation
(GO:0021940)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of mesenchymal cell proliferation
(GO:0002053)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of skeletal muscle cell proliferation
(GO:0014858)
Positive regulation of wnt signaling pathway
(GO:0030177)
Prostate gland development
(GO:0030850)
Protein autoprocessing
(GO:0016540)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of epithelial cell differentiation
(GO:0030856)
Regulation of gene expression
(GO:0010468)
Regulation of proteolysis
(GO:0030162)
Respiratory tube development
(GO:0030323)
Response to hypoxia
(GO:0001666)
Response to organonitrogen compound
(GO:0010243)
Skeletal muscle cell proliferation
(GO:0014856)
Skeletal muscle tissue development
(GO:0007519)
Smoothened signaling pathway
(GO:0007224)
Spinal cord dorsal/ventral patterning
(GO:0021513)
Spinal cord motor neuron differentiation
(GO:0021522)
Striated muscle tissue development
(GO:0014706)
Telencephalon regionalization
(GO:0021978)
Thalamus development
(GO:0021794)
Thyroid gland development
(GO:0030878)
Vasculature development
(GO:0001944)
Vasculogenesis
(GO:0001570)
Ventral spinal cord interneuron specification
(GO:0021521)
Zinc ion binding
(GO:0008270)
Zona limitans intrathalamica formation
(GO:0022006)

Other Information

Proteins

Sonic hedgehog protein N-product

Genular Protein ID: 3666969377

Symbol: SHH_RAT

Name: Sonic hedgehog protein N-product

UniProtKB Accession Codes:

Q63673

Database IDs:

Citations:

PubMed ID: 8124714

Title: Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

PubMed ID: 8124714

DOI: 10.1016/0092-8674(94)90514-2

PubMed ID: 11395778

Title: A freely diffusible form of Sonic hedgehog mediates long-range signalling.

PubMed ID: 11395778

DOI: 10.1038/35079648

Sequence Information:

Length: 437
Mass: 47630
Checksum: 0DBFC19F0D1662A0
Sequence:

MLLLLARCFL VALASSLLVC PGLACGPGRG FGKRQHPKKL TPLAYKQFIP NVAEKTLGAS 
GRYEGKITRN SERFKELTPN YNPDIIFKDE ENTGADRLMT QRCKDKLNAL AISVMNQWPG 
VKLRVTEGWD EDGHHSEESL HYEGRAVDIT TSDRDRSKYG MLARLAVEAG FDWVYYESKA 
RIHCSVKAEN SVAAKSDGCF PGSATVHLEQ GGTKLVKDLS PGDRVLAADD QGRLLYSDFL 
TFLDRDEGAK KVFYVIETRE PRERLLLTAA HLLFVAPHND SGPTPGPSPL FASRVRPGQR 
VYVVAERGGD RRLLPAAVHS VTLREEAAGA YAPLTADGTI LINRVLASCY AVIEEHSWAH 
RAFAPFRLAH ALLAALAPAR TDGGGGGSIP APQSVAEARG AGPPAGIHWY SQLLYHIGTW 
LLDSETLHPL GMAVKSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.