Details for: Slc22a2

Gene ID: 29503

Symbol: Slc22a2

Ensembl ID: ENSRNOG00000016625

Description: solute carrier family 22 member 2

Associated with

Other Information

Genular Protein ID: 362795387

Symbol: S22A2_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8702418

Title: cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

PubMed ID: 8702418

DOI: 10.1006/bbrc.1996.1056

PubMed ID: 9260930

Title: Cloning and characterization of two human polyspecific organic cation transporters.

PubMed ID: 9260930

DOI: 10.1089/dna.1997.16.871

PubMed ID: 10385678

Title: Selective substrates for non-neuronal monoamine transporters.

PubMed ID: 10385678

DOI: 10.1124/mol.56.1.1

PubMed ID: 9812985

Title: Transport of monoamine transmitters by the organic cation transporter type 2, OCT2.

PubMed ID: 9812985

DOI: 10.1074/jbc.273.47.30915

PubMed ID: 9830022

Title: Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.

PubMed ID: 9830022

DOI: 10.1074/jbc.273.49.32776

PubMed ID: 10812069

Title: Hormonal regulation of organic cation transporter OCT2 expression in rat kidney.

PubMed ID: 10812069

DOI: 10.1016/s0014-5793(00)01525-8

PubMed ID: 10889205

Title: Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.

PubMed ID: 10889205

DOI: 10.1074/jbc.m004645200

PubMed ID: 11758759

Title: Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.

PubMed ID: 11758759

DOI: 10.1023/a:1013070128668

PubMed ID: 11083459

Title: Differential localization of organic cation transporters rOCT1 and rOCT2 in the basolateral membrane of rat kidney proximal tubules.

PubMed ID: 11083459

DOI: 10.1007/s004180000186

PubMed ID: 12538837

Title: Agmatine is efficiently transported by non-neuronal monoamine transporters extraneuronal monoamine transporter (EMT) and organic cation transporter 2 (OCT2).

PubMed ID: 12538837

DOI: 10.1124/jpet.102.044404

PubMed ID: 16242669

Title: Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat.

PubMed ID: 16242669

DOI: 10.1016/j.bcp.2005.09.020

PubMed ID: 16272756

Title: Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

PubMed ID: 16272756

DOI: 10.2133/dmpk.20.379

PubMed ID: 16006492

Title: A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.

PubMed ID: 16006492

DOI: 10.1124/jpet.105.088104

PubMed ID: 17567940

Title: Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.

PubMed ID: 17567940

DOI: 10.1152/ajprenal.00106.2007

PubMed ID: 15817714

Title: Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium.

PubMed ID: 15817714

DOI: 10.1165/rcmb.2004-0363oc

PubMed ID: 16581093

Title: Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain.

PubMed ID: 16581093

DOI: 10.1016/j.neuropharm.2006.01.005

PubMed ID: 17582384

Title: Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity.

PubMed ID: 17582384

DOI: 10.1016/j.bcp.2007.03.004

PubMed ID: 18180268

Title: Altered pharmacokinetics of cationic drugs caused by down-regulation of renal rat organic cation transporter 2 (slc22a2) and rat multidrug and toxin extrusion 1 (slc47a1) in ischemia/reperfusion-induced acute kidney injury.

PubMed ID: 18180268

DOI: 10.1124/dmd.107.019869

Sequence Information:

  • Length: 555
  • Mass: 62343
  • Checksum: 29521969AE1AC206
  • Sequence:
  • MSTVDDILEH IGEFHLFQKQ TFFLLALLSG AFTPIYVGIV FLGFTPDHHC WSPGAAKLSQ 
    RCGWSQAEEL NYTVPGLGPS DEASFLSQCM RYEVDWNQST LDCVDPLSSL AADRNQLPLG 
    PCEHGWVYNT PGSSIVTEFN LVCAHSWMLD LFQSVVNVGF FIGAMMIGYL ADRFGRKFCL 
    LVTILINAIS GALMAISPNY AWMLVFRFLQ GLVSKAGWLI GYILITEFVG LGYRRMVGIC 
    YQIAFTVGLL ILAGVAYVIP NWRWLQFAVT LPNFCFLLYF WCIPESPRWL ISQNKIVKAM 
    KIIKHIAKKN GKSVPVSLQN LTPDEDAGKK LNPSFLDLVR TPQIRKHTLI LMYNWFTSSV 
    LYQGLIMHMG LAGDNIYLDF FYSALVEFPA AFIIILTIDR VGRRYPWAVS NMVAGAACLA 
    SVFIPDDLQW LKITIACLGR MGITMAYEMV CLVNAELYPT YIRNLGVLVC SSMCDIGGII 
    TPFLVYRLTD IWMEFPLVVF AVVGLVAGAL VLLLPETKGK ALPETIEDAE NMQRPRKKKE 
    KRIYLQVKQA DRPLS

Genular Protein ID: 1967607238

Symbol: A0A0G2JSP9_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 593
  • Mass: 66081
  • Checksum: 36C1044E0C04B443
  • Sequence:
  • MSTVDDILEH IGEFHLFQKQ TFFLLALLSG AFTPIYVGIV FLGFTPDHHC WSPGAAKLSQ 
    RCGWSQAEEL NYTVPGLGPS DEASFLSQCM RYEVDWNQST LDCVDPLSSL AADRNQLPLG 
    PCEHGWVYNT PGSSIVTEFN LVCAHSWMLD LFQSVVNVGF FIGAMMIGYL ADRFGRKFCL 
    LVTILINAIS GALMAISPNY AWMLVFRFLQ GLVSKAGWLI GYILITEFVG LGYRRMVGIC 
    YQIAFTVGLL ILAGVAYVIP NWRWLQFAVT LPNFCFLLYF WCIPESPRWL ISQNKIVKAM 
    KIIKHIAKKN GKSVPVSLQN LTPDEDAGKK LKPSILDLVR TPQIRKHTLI LMYNWFTSSV 
    LYQGLIMHMG LAGDNIYLDF FYSALVEFPA AFIIILTIDR VGRRYPWAVS NMVAGAACLA 
    SVFIPDDLQW LKITIACLGR MGITMAYEMV CLVNAELYPT YIRNLGVLVC SSMCDIGGII 
    TPFLVYRLTD IWMEFPLVVF AVVGLVAGAL VLLLPETKGK ALPETIEDAE NMQRPRKKER 
    KENLPPSQAS RPSAKLKRKG IIAAGADFAL SEARDGASLS PPPKPTQTNL TYP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.