Pde3b | ENSRNOG00000011417 | NCBI 29516

Details for: Pde3b

Gene ID: 29516

Symbol: Pde3b

Ensembl ID: ENSRNOG00000011417

Description: phosphodiesterase 3B

Associated with

G alpha (s) signalling events
(R-RNO-418555)
Gpcr downstream signalling
(R-RNO-388396)
Igf1r signaling cascade
(R-RNO-2428924)
Insulin receptor signalling cascade
(R-RNO-74751)
Irs-mediated signalling
(R-RNO-112399)
Irs-related events triggered by igf1r
(R-RNO-2428928)
Pde3b signalling
(R-RNO-165160)
Pi3k cascade
(R-RNO-109704)
Pkb-mediated events
(R-RNO-109703)
Signaling by gpcr
(R-RNO-372790)
Signaling by insulin receptor
(R-RNO-74752)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-RNO-2404192)
3',5'-cyclic-amp phosphodiesterase activity
(GO:0004115)
3',5'-cyclic-gmp phosphodiesterase activity
(GO:0047555)
3',5'-cyclic-nucleotide phosphodiesterase activity
(GO:0004114)
Angiogenesis
(GO:0001525)
Camp-mediated signaling
(GO:0019933)
Cellular response to insulin stimulus
(GO:0032869)
Endocrine pancreas development
(GO:0031018)
Endoplasmic reticulum
(GO:0005783)
Glucose homeostasis
(GO:0042593)
Golgi apparatus
(GO:0005794)
Guanyl-nucleotide exchange factor complex
(GO:0032045)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of camp-mediated signaling
(GO:0043951)
Negative regulation of cell adhesion
(GO:0007162)
Negative regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0061179)
Negative regulation of lipid catabolic process
(GO:0050995)
Phosphoprotein binding
(GO:0051219)
Protein kinase b binding
(GO:0043422)
Regulation of angiogenesis
(GO:0045765)
Regulation of insulin secretion
(GO:0050796)
Regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051896)
Signal transduction
(GO:0007165)

Other Information

Proteins

CGI PDE

Genular Protein ID: 3504099518

Symbol: PDE3B_RAT

Name: CGI PDE

UniProtKB Accession Codes:

Q63085

Database IDs:

Citations:

PubMed ID: 8395509

Title: Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase.

PubMed ID: 8395509

DOI: 10.1016/s0021-9258(17)46666-x

PubMed ID: 9631240

Title: Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).

PubMed ID: 9631240

DOI: 10.1007/bf02737830

Sequence Information:

Length: 1108
Mass: 123107
Checksum: C9B5078C7D3ADD6D
Sequence:

MRKDERERDT PAMRSPPPPP PPATATAASP PESLRNGYVK SCVSPLRQDP PRSFFFHLCR 
FCNVEPPAAS LRAGARLSLA ALAAFVLAAL LGAGPERWAA AATGLRTLLS ACSLSLSPLF 
SIACAFFFLT CFLTRAQRGP DRGAGSWWLL ALPACCYLGD FAAWQWWSWL RGEPAAAAAG 
RLCLVLSCVG LLTLAPRVRL RHGVLVLLFA GLVWWVSFSG LGALPPALRP LLSCLVGGAG 
CLLALGLDHF FHVRGASPPP RSASTADEKV PVIRPRRRSS CVSLGESAAG YYGSGKMFRR 
PSLPCISREQ MILWDWDLKQ WCKPHYQNSG GGNGVDLSVL NEARNMVSDL LIDPSLPPQV 
ISSLRSISSL MGAFSGSCRP KINSFTPFPG FYPCSEVEDP VEKGDRKLHK GLSSKPSFPT 
AQLRRSSGAS GLLTSEHHSR WDRSGGKRPY QELSVSSHGC HLNGPFSSNL MTIPKQRSSS 
VSLTHHAGLR RAGALPSPSL LNSSSHVPVS AGCLTNRSPV GFLDTSDFLT KPSVTLHRSL 
GSVSSAADFH QYLRNSDSSL CSSCGHQILK YVSTCEPDGT DHHNEKSGEE DSTVFSKERL 
NIVETQEEET VKEDCRELFL EGDDHLMEEA QQPNIDQEVL LDPMLVEDYD SLIEKMSNWN 
FQIFELVEKM GEKSGRILSQ VMYTLFQDTG LLETFKIPTQ EFMNYFRALE NGYRDIPYHN 
RVHATDVLHA VWYLTTRPIP GLQQLHNNHE TETKADSDAR LSSGQIAYLS SKSCCIPDKS 
YGCLSSNIPA LELMALYVAA AMHDYDHPGR TNAFLVATNA PQAVLYNDRS VLENHHAASA 
WNLYLSRPEY NFLLNLDHME FKRFRFLVIE AILATDLKKH FDFLAEFNAK ANDVNSNGIE 
WSSENDRLLV CQVCIKLADI NGPAKDRDLH LRWTEGIVNE FYEQGDEEAT LGLPISPFMD 
RSSPQLAKLQ ESFITHIVGP LCNSYDAAGL LPGQWIEAEE GDDTESDDDD DDDDDDDDDD 
DEELDSDDEE TEDNLNPKPQ RRKGRRRIFC QLMHHLTENH KIWKEIIEEE EKCKAEGNKL 
QVDNASLPQA DEIQVIEEAD EEEEQMFE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.