Pdx1 | ENSRNOG00000046458 | NCBI 29535

Details for: Pdx1

Gene ID: 29535

Symbol: Pdx1

Ensembl ID: ENSRNOG00000046458

Description: pancreatic and duodenal homeobox 1

Associated with

Animal organ regeneration
(GO:0031100)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Chromatin binding
(GO:0003682)
Cytosol
(GO:0005829)
Digestive tract development
(GO:0048565)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-templated transcription
(GO:0006351)
Endocrine pancreas development
(GO:0031018)
Enteroendocrine cell differentiation
(GO:0035883)
Epithelial cell proliferation
(GO:0050673)
Exocrine pancreas development
(GO:0031017)
Glucose homeostasis
(GO:0042593)
Glucose mediated signaling pathway
(GO:0010255)
Glucose metabolic process
(GO:0006006)
Insulin secretion
(GO:0030073)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
(GO:0070059)
Liver development
(GO:0001889)
Morphogenesis of embryonic epithelium
(GO:0016331)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
(GO:1902236)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of type b pancreatic cell apoptotic process
(GO:2000675)
Nitric oxide mediated signal transduction
(GO:0007263)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pancreas development
(GO:0031016)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of type b pancreatic cell proliferation
(GO:1904692)
Promoter-specific chromatin binding
(GO:1990841)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of cell population proliferation
(GO:0042127)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to alkaloid
(GO:0043279)
Response to chlorate
(GO:0010157)
Response to cytokine
(GO:0034097)
Response to fatty acid
(GO:0070542)
Response to glucocorticoid
(GO:0051384)
Response to glucose
(GO:0009749)
Response to iron(ii) ion
(GO:0010040)
Response to leucine
(GO:0043201)
Response to lipid
(GO:0033993)
Response to nicotine
(GO:0035094)
Response to nutrient levels
(GO:0031667)
Response to organic cyclic compound
(GO:0014070)
Response to vitamin
(GO:0033273)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Smoothened signaling pathway
(GO:0007224)
Stem cell differentiation
(GO:0048863)
Transcription by rna polymerase ii
(GO:0006366)
Transdifferentiation
(GO:0060290)
Type b pancreatic cell apoptotic process
(GO:0097050)
Type b pancreatic cell differentiation
(GO:0003309)
Type b pancreatic cell proliferation
(GO:0044342)

Other Information

Proteins

Pancreas/duodenum homeobox protein 1

Genular Protein ID: 2597820626

Symbol: PDX1_RAT

Name: Pancreas/duodenum homeobox protein 1

UniProtKB Accession Codes:

P52947

Database IDs:

Citations:

PubMed ID: 7907546

Title: IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene.

PubMed ID: 7907546

DOI: 10.1002/j.1460-2075.1994.tb06363.x

PubMed ID: 7505393

Title: Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.

PubMed ID: 7505393

DOI: 10.1210/mend.7.10.7505393

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 283
Mass: 30831
Checksum: C8C25FF2C75ED4E6
Sequence:

MNSEEQYYAA TQLYKDPCAF QRGPVPEFSA NPPACLYMGR QPPPPPPPQF AGSLGTLEQG 
SPPDISPYEV PPLADDPAGA HLHHHLPAQL GLAHPPPGPF PNGTETGGLE EPSRVHLPFP 
WMKSTKAHAW KSQWAGGAYA AEPEENKRTR TAYTRAQLLE LEKEFLFNKY ISRPRRVELA 
VMLNLTERHI KIWFQNRRMK WKKEEDKKRS SGTTSGGGGG EEPEQDCAVT SGEELLALPP 
PPPPGGAVPS GVPAAAREGR LPSGLSASPQ PSSIAPLRPQ EPR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.