Timp2 | ENSRNOG00000033143 | NCBI 29543

Details for: Timp2

Gene ID: 29543

Symbol: Timp2

Ensembl ID: ENSRNOG00000033143

Description: TIMP metallopeptidase inhibitor 2

Associated with

Activation of matrix metalloproteinases
(R-RNO-1592389)
Degradation of the extracellular matrix
(R-RNO-1474228)
Extracellular matrix organization
(R-RNO-1474244)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Neutrophil degranulation
(R-RNO-6798695)
Basement membrane
(GO:0005604)
Cell surface
(GO:0009986)
Cellular response to organic substance
(GO:0071310)
Enzyme activator activity
(GO:0008047)
Extracellular matrix
(GO:0031012)
Extracellular space
(GO:0005615)
Growth cone
(GO:0030426)
Integrin binding
(GO:0005178)
Metalloendopeptidase inhibitor activity
(GO:0008191)
Molecular function inhibitor activity
(GO:0140678)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of membrane protein ectodomain proteolysis
(GO:0051045)
Negative regulation of mitotic cell cycle
(GO:0045930)
Negative regulation of proteolysis
(GO:0045861)
Negative regulation of ras protein signal transduction
(GO:0046580)
Neuronal cell body
(GO:0043025)
Peptidase inhibitor activity
(GO:0030414)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron differentiation
(GO:0045666)
Protease binding
(GO:0002020)
Regulation of mapk cascade
(GO:0043408)
Regulation of neuron differentiation
(GO:0045664)
Regulation of rap protein signal transduction
(GO:0032487)
Response to cytokine
(GO:0034097)
Response to hormone
(GO:0009725)
Response to xenobiotic stimulus
(GO:0009410)
Spermatogenesis
(GO:0007283)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Metalloproteinase inhibitor 2

Genular Protein ID: 3721479308

Symbol: TIMP2_RAT

Name: Metalloproteinase inhibitor 2

UniProtKB Accession Codes:

P30121 Q546J4

Database IDs:

Citations:

PubMed ID: 8203893

Title: Cloning and regulation of rat tissue inhibitor of metalloproteinases-2 in osteoblastic cells.

PubMed ID: 8203893

DOI: 10.1006/abbi.1994.1243

PubMed ID: 8050496

Title: Cloning of the rat tissue inhibitor of metalloproteinases type 2 (TIMP-2) gene: analysis of its expression in normal and transformed thyroid cells.

PubMed ID: 8050496

DOI: 10.1006/excr.1994.1215

PubMed ID: 8792217

Title: Purification, cDNA cloning, and developmental changes in the steady-state mRNA level of rat testicular tissue inhibitor of metalloproteases-2 (TIMP-2).

PubMed ID: 8792217

PubMed ID: 11684074

Title: Cardiac remodeling after long term norepinephrine treatment in rats.

PubMed ID: 11684074

DOI: 10.1016/s0008-6363(01)00398-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1309971

Title: Purification and sequence analysis of two rat tissue inhibitors of metalloproteinases.

PubMed ID: 1309971

DOI: 10.1016/0003-9861(92)90009-l

Sequence Information:

Length: 220
Mass: 24356
Checksum: 1C97A3F050C3AE7D
Sequence:

MGAAARSLRL ALGLLLLATL LRPADACSCS PVHPQQAFCN ADVVIRAKAV SEKEVDSGND 
IYGNPIKRIQ YEIKQIKMFK GPDKDIEFIY TAPSSAVCGV SLDVGGKKEY LIAGKAEGDG 
KMHITLCDFI VPWDTLSITQ KKSLNHRYQM GCECKITRCP MIPCYISSPD ECLWMDWVTE 
KSINGHQAKF FACIKRSDGS CAWYRGAAPP KQEFLDIEDP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Timp2

Associated with

Other Information

Cloning and regulation of rat tissue inhibitor of metalloproteinases-2 in osteoblastic cells. PubMed ID: 8203893

Cloning of the rat tissue inhibitor of metalloproteinases type 2 (TIMP-2) gene: analysis of its expression in normal and transformed thyroid cells. PubMed ID: 8050496

Purification, cDNA cloning, and developmental changes in the steady-state mRNA level of rat testicular tissue inhibitor of metalloproteases-2 (TIMP-2). PubMed ID: 8792217

Cardiac remodeling after long term norepinephrine treatment in rats. PubMed ID: 11684074

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334