Hif1a | ENSRNOG00000008292 | NCBI 29560

Details for: Hif1a

Gene ID: 29560

Symbol: Hif1a

Ensembl ID: ENSRNOG00000008292

Description: hypoxia inducible factor 1 subunit alpha

Associated with

Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to hypoxia
(R-RNO-1234174)
Deubiquitination
(R-RNO-5688426)
Metabolism of proteins
(R-RNO-392499)
Neddylation
(R-RNO-8951664)
Oxygen-dependent proline hydroxylation of hypoxia-inducible factor alpha
(R-RNO-1234176)
Post-translational protein modification
(R-RNO-597592)
Ptk6 promotes hif1a stabilization
(R-RNO-8857538)
Regulation of gene expression by hypoxia-inducible factor
(R-RNO-1234158)
Signaling by non-receptor tyrosine kinases
(R-RNO-9006927)
Signaling by ptk6
(R-RNO-8848021)
Ub-specific processing proteases
(R-RNO-5689880)
Acute-phase response
(GO:0006953)
Angiogenesis
(GO:0001525)
Apoptotic process
(GO:0006915)
Axonal transport of mitochondrion
(GO:0019896)
B-1 b cell homeostasis
(GO:0001922)
Blood vessel development
(GO:0001568)
Cardiac ventricle morphogenesis
(GO:0003208)
Cerebral cortex development
(GO:0021987)
Chondrocyte differentiation
(GO:0002062)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Connective tissue replacement involved in inflammatory response wound healing
(GO:0002248)
Dna-binding transcription activator activity
(GO:0001216)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity
(GO:0001217)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Embryonic placenta development
(GO:0001892)
Enzyme binding
(GO:0019899)
Epithelial to mesenchymal transition
(GO:0001837)
Glandular epithelial cell differentiation
(GO:0002067)
Glandular epithelial cell maturation
(GO:0002071)
Heart looping
(GO:0001947)
Histone deacetylase binding
(GO:0042826)
Hsp90 protein binding
(GO:0051879)
Intracellular glucose homeostasis
(GO:0001678)
Intracellular iron ion homeostasis
(GO:0006879)
Lactate metabolic process
(GO:0006089)
Lactation
(GO:0007595)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural crest cell migration
(GO:0001755)
Neural fold elevation formation
(GO:0021502)
Neuroblast proliferation
(GO:0007405)
Nuclear receptor binding
(GO:0016922)
Outflow tract morphogenesis
(GO:0003151)
P53 binding
(GO:0002039)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of macroautophagy
(GO:0016239)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein heterodimerization activity
(GO:0046982)
Protein kinase binding
(GO:0019901)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of glycolytic process
(GO:0006110)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to activity
(GO:0014823)
Response to auditory stimulus
(GO:0010996)
Response to glucose
(GO:0009749)
Response to hypoxia
(GO:0001666)
Response to iron ion
(GO:0010039)
Response to mechanical stimulus
(GO:0009612)
Response to muscle activity
(GO:0014850)
Response to purine-containing compound
(GO:0014074)
Response to reactive oxygen species
(GO:0000302)
Response to salt stress
(GO:0009651)
Response to x-ray
(GO:0010165)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific dna binding
(GO:0043565)
Signal transduction
(GO:0007165)
Transcription coactivator binding
(GO:0001223)
Transcription regulator activator activity
(GO:0140537)
Ubiquitin protein ligase binding
(GO:0031625)
Vascular endothelial growth factor production
(GO:0010573)
Vasculature development
(GO:0001944)
Visual learning
(GO:0008542)

Other Information

Proteins

Hypoxia-inducible factor 1-alpha

Genular Protein ID: 3707221954

Symbol: HIF1A_RAT

Name: Hypoxia-inducible factor 1-alpha

UniProtKB Accession Codes:

O35800 Q9WTU9

Database IDs:

Citations:

PubMed ID: 11237857

Title: Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver.

PubMed ID: 11237857

DOI: 10.1042/0264-6021:3540531

PubMed ID: 11526200

Title: Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats.

PubMed ID: 11526200

DOI: 10.1152/physiolgenomics.2001.6.3.159

Sequence Information:

Length: 825
Mass: 92319
Checksum: C4109A57F38667E9
Sequence:

MEGAGGENEK KKMSSERRKE KSRDAARSRR SKESEVFYEL AHQLPLPHNV SSHLDKASVM 
RLTISYLRVR KLLDAGDLDI EDEMKAQMNC FYLKAPDGFV MVLTDDGDMI YISDNVNKYM 
GLTQFELTGH SVFDFTHPCD HEEMREMLTH RNGPVRKGKE QNTQRSFFLR MKCTLTSRGR 
TMNIKSATWK VLHCTGHIHV YDTSSNQPQC GYKKPPMTCL VLICEPIPHP SNIEIPLDSK 
TFLSRHSLDM KFSYCDERIT ELMGYEPEEL LGRSIYEYYH ALDSDHLTKT HHDMFTKGQV 
TTGQYRMLAK RGGYVWVETQ ATVIYNTKDS QPQCIVCVNY VVSGIIQHDL IFSLQQTESV 
LKPVESSDMK MTQLFTKVES EDTSCLFDKL KKEPDALTLL APAAGDTIIS LDFGSDDTET 
EDQQLEDVPL YNDVMFPSSN EKLNINLAMS PLPASETPKP LRSSADPALN QEVALKLESS 
PESLGLSFTM PQIQDQPASP SDGSTRQSSP EPNSPSEYCF DVDSDMVNVF KLELVEKLFA 
EDTEAKNPFS AQDTDLDLEM LAPYIPMDDD FQLRSFDQLS PLESNSPSPP SVSTVTGFQQ 
TQLQKPTITV TAATATTATT TDESKAVTKD NIEDIKILIA SPPSTQVPQE MTTAKASAYS 
GTHSRTASPD RAGKRVIEKT DKAHPRSLNL SVTLNQRNTV PEEELNPRTI ALQNAQRKRK 
MEHDGSLFQA AGIGTLLQQP GDRAPTMSLS WKRVKGYISS EQDGMEQKTI FLIPSDLACR 
LLGQSMDESG LPQLTSYDCE VNAPIQGSRN LLQGEELLRA LDQVN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.