Eef2 | ENSRNOG00000020266 | NCBI 29565

Details for: Eef2

Gene ID: 29565

Symbol: Eef2

Ensembl ID: ENSRNOG00000020266

Description: eukaryotic translation elongation factor 2

Associated with

Eukaryotic translation elongation
(R-RNO-156842)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-RNO-163841)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Metabolism of proteins
(R-RNO-392499)
Neutrophil degranulation
(R-RNO-6798695)
Peptide chain elongation
(R-RNO-156902)
Post-translational protein modification
(R-RNO-597592)
Protein methylation
(R-RNO-8876725)
Synthesis of diphthamide-eef2
(R-RNO-5358493)
5s rrna binding
(GO:0008097)
Actin filament binding
(GO:0051015)
Aggresome
(GO:0016235)
Cellular response to brain-derived neurotrophic factor stimulus
(GO:1990416)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Glial cell proliferation
(GO:0014009)
Glutamatergic synapse
(GO:0098978)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Nucleus
(GO:0005634)
P53 binding
(GO:0002039)
Plasma membrane
(GO:0005886)
Positive regulation of cytoplasmic translation
(GO:2000767)
Positive regulation of translation
(GO:0045727)
Postsynapse
(GO:0098794)
Protein kinase binding
(GO:0019901)
Response to endoplasmic reticulum stress
(GO:0034976)
Response to estradiol
(GO:0032355)
Response to ethanol
(GO:0045471)
Response to folic acid
(GO:0051593)
Response to hydrogen peroxide
(GO:0042542)
Response to ischemia
(GO:0002931)
Response to xenobiotic stimulus
(GO:0009410)
Ribonucleoprotein complex
(GO:1990904)
Ribosome
(GO:0005840)
Ribosome binding
(GO:0043022)
Rna binding
(GO:0003723)
Skeletal muscle cell differentiation
(GO:0035914)
Skeletal muscle contraction
(GO:0003009)
Synapse
(GO:0045202)
Translation
(GO:0006412)
Translational elongation
(GO:0006414)
Translation at postsynapse
(GO:0140242)
Translation elongation factor activity
(GO:0003746)

Other Information

Proteins

Elongation factor 2

Genular Protein ID: 607536278

Symbol: EF2_RAT

Name: Elongation factor 2

UniProtKB Accession Codes:

P05197 P97619

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2721670

Title: Primary structure of rat liver elongation factor 2 deduced from the cDNA sequence.

PubMed ID: 2721670

DOI: 10.1016/0014-5793(89)80447-8

PubMed ID: 3014523

Title: Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins.

PubMed ID: 3014523

DOI: 10.1073/pnas.83.14.4978

PubMed ID: 4368673

Title: Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate ribosylation.

PubMed ID: 4368673

DOI: 10.1016/s0021-9258(19)42331-4

PubMed ID: 3693353

Title: Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.

PubMed ID: 3693353

DOI: 10.1016/s0021-9258(18)45377-x

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 858
Mass: 95284
Checksum: D6F7A61BADD4B137
Sequence:

MVNFTVDQIR AIMDKKANIR NMSVIAHVDH GKSTLTDSLV CKAGIIASAR AGETRFTDTR 
KDEQERCITI KSTAISLFYE LSENDLNFIK QSKDGSGFLI NLIDSPGHVD FSSEVTAALR 
VTDGALVVVD CVSGVCVQTE TVLRQAIAER IKPVLMMNKM DRALLELQLE PEELYQTFQR 
IVENVNVIIS TYGEGESGPM GNIMIDPVLG TVGFGSGLHG WAFTLKQFAE MYVAKFAAKG 
EGQLGAAERA KKVEDMMKKL WGDRYFDPAN GKFSKSANSP DGKKLPRTFC QLILDPIFKV 
FDAIMNFRKE ETAKLIEKLD IKLDSEDKDK EGKPLLKAVM RRWLPAGDAL LQMITIHLPS 
PVTAQKYRCE LLYEGPPDDE AAMGIKSCDP KGPLMMYISK MVPTSDKGRF YAFGRVFSGV 
VSTGLKVRIM GPNYTPGKKE DLYLKPIQRT ILMMGRYVEP IEDVPCGNIV GLVGVDQFLV 
KTGTITTFEH AHNMRVMKFS VSPVVRVAVE AKNPADLPKL VEGLKRLAKS DPMVQCIIEE 
SGEHIIAGAG ELHLEICLKD LEEDHACIPI KKSDPVVSYR ETVSEESNVL CLSKSPNKHN 
RLYMKARPFP DGLAEDIDKG EVSARQELKA RARYLAEKYE WDVAEARKIW CFGPDGTGPN 
ILTDITKGVQ YLNEIKDSVV AGFQWATKEG ALCEENMRGV RFDVHDVTLH ADAIHRGGGQ 
IIPTARRCLY ASVLTAQPRL MEPIYLVEIQ CPEQVVGGIY GVLNRKRGHV FEESQVAGTP 
MFVVKAYLPV NESFGFTADL RSNTGGQAFP QCVFDHWQIL PGDPFDNSSR PSQVVAETRK 
RKGLKEGIPA LDNFLDKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Eef2

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Primary structure of rat liver elongation factor 2 deduced from the cDNA sequence. PubMed ID: 2721670

Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins. PubMed ID: 3014523

Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate ribosylation. PubMed ID: 4368673

Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2. PubMed ID: 3693353