Hes1 | ENSRNOG00000001720 | NCBI 29577

Details for: Hes1

Gene ID: 29577

Symbol: Hes1

Ensembl ID: ENSRNOG00000001720

Description: hes family bHLH transcription factor 1

Associated with

Adenohypophysis development
(GO:0021984)
Amacrine cell differentiation
(GO:0035881)
Anterior/posterior pattern specification
(GO:0009952)
Aorta morphogenesis
(GO:0035909)
Artery morphogenesis
(GO:0048844)
Ascending aorta morphogenesis
(GO:0035910)
Bmp signaling pathway
(GO:0030509)
Cajal-retzius cell differentiation
(GO:0021870)
Cell adhesion
(GO:0007155)
Cell fate commitment
(GO:0045165)
Cell fate determination
(GO:0001709)
Cell maturation
(GO:0048469)
Cell migration
(GO:0016477)
Cell morphogenesis involved in neuron differentiation
(GO:0048667)
Cell population proliferation
(GO:0008283)
Chromatin binding
(GO:0003682)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity
(GO:0001217)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Embryonic heart tube morphogenesis
(GO:0003143)
Forebrain radial glial cell differentiation
(GO:0021861)
Hair cell differentiation
(GO:0035315)
Hindbrain morphogenesis
(GO:0021575)
Histone deacetylase binding
(GO:0042826)
Hlh domain binding
(GO:0043398)
Identical protein binding
(GO:0042802)
Inhibition of neuroepithelial cell differentiation
(GO:0002085)
Inner ear auditory receptor cell differentiation
(GO:0042491)
In utero embryonic development
(GO:0001701)
Jun kinase binding
(GO:0008432)
Lateral inhibition
(GO:0046331)
Liver development
(GO:0001889)
Lung development
(GO:0030324)
Midbrain-hindbrain boundary morphogenesis
(GO:0021555)
Midbrain development
(GO:0030901)
N-box binding
(GO:0071820)
Negative regulation of cell differentiation
(GO:0045596)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of inner ear auditory receptor cell differentiation
(GO:0045608)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of neuron projection development
(GO:0010977)
Negative regulation of oligodendrocyte differentiation
(GO:0048715)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural tube development
(GO:0021915)
Neuron differentiation
(GO:0030182)
Notch signaling pathway
(GO:0007219)
Oculomotor nerve development
(GO:0021557)
Outflow tract morphogenesis
(GO:0003151)
Pancreas development
(GO:0031016)
Pancreatic a cell differentiation
(GO:0003310)
Pattern specification process
(GO:0007389)
Pituitary gland development
(GO:0021983)
Positive regulation of astrocyte differentiation
(GO:0048711)
Positive regulation of bmp signaling pathway
(GO:0030513)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glial cell differentiation
(GO:0045687)
Positive regulation of mitotic cell cycle, embryonic
(GO:0045977)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of receptor signaling pathway via jak-stat
(GO:0046427)
Positive regulation of t cell proliferation
(GO:0042102)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of tyrosine phosphorylation of stat protein
(GO:0042531)
Protein-containing complex binding
(GO:0044877)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of fat cell differentiation
(GO:0045598)
Regulation of neuron differentiation
(GO:0045664)
Regulation of protein-containing complex assembly
(GO:0043254)
Regulation of receptor signaling pathway via jak-stat
(GO:0046425)
Regulation of secondary heart field cardioblast proliferation
(GO:0003266)
Regulation of timing of cell differentiation
(GO:0048505)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to alkaloid
(GO:0043279)
Response to organic cyclic compound
(GO:0014070)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Smoothened signaling pathway
(GO:0007224)
Somatic stem cell population maintenance
(GO:0035019)
T cell proliferation
(GO:0042098)
Telencephalon development
(GO:0021537)
Thymus development
(GO:0048538)
Transcription corepressor binding
(GO:0001222)
Trochlear nerve development
(GO:0021558)
Ventricular septum development
(GO:0003281)

Other Information

Proteins

Transcription factor HES-1

Genular Protein ID: 1678576233

Symbol: HES1_RAT

Name: Transcription factor HES-1

UniProtKB Accession Codes:

Q04666

Database IDs:

Citations:

PubMed ID: 1340473

Title: Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.

PubMed ID: 1340473

DOI: 10.1101/gad.6.12b.2620

PubMed ID: 8417318

Title: A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation.

PubMed ID: 8417318

DOI: 10.1128/mcb.13.1.105-113.1993

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8687460

Title: Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif.

PubMed ID: 8687460

DOI: 10.1006/bbrc.1996.0959

PubMed ID: 8649374

Title: The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain.

PubMed ID: 8649374

DOI: 10.1128/mcb.16.6.2670

Sequence Information:

Length: 281
Mass: 29622
Checksum: 8A98C8964F075B0D
Sequence:

MPADIMEKNS SSPVAATPAS VNTTPDKPKT ASEHRKSSKP IMEKRRRARI NESLSQLKTL 
ILDALKKDSS RHSKLEKADI LEMTVKHLRN LQRAQMTAAL STDPSVLGKY RAGFSECMNE 
VTRFLSTCEG VNTEVRTRLL GHLANCMTQI NAMTYPGQAH PALQAPPPPP PSGPGGPQHA 
PFAPPPPLVP IPGGAAPPPG SAPCKLGSQA GEAAKVFGGF QVVPAPDGQF AFLIPNGAFA 
HSGPVIPVYT SNSGTSVGPN AVSPSSGSSL TADSMWRPWR N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hes1

Associated with

Other Information

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. PubMed ID: 1340473

A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. PubMed ID: 8417318

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334