Details for: Fdft1

Gene ID: 29580

Symbol: Fdft1

Ensembl ID: ENSRNOG00000021314

Description: farnesyl diphosphate farnesyl transferase 1

Associated with

Other Information

Genular Protein ID: 2006837094

Symbol: FDFT_RAT

Name: Squalene synthase

UniProtKB Accession Codes:

Q02769

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 Bgee 1 BindingDB 1 CDD 1 CTD 1 ChEBI 36 ChEMBL 1 DrugCentral 1 EC 2 EMBL 2 Ensembl 2 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 1 Rhea 10 SFLD 2 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 eggNOG 1 jPOST 1

Citations:

PubMed ID: 1569107

Title: Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase.

PubMed ID: 1569107

DOI: 10.1016/s0021-9258(18)42489-1

PubMed ID: 1400448

Title: Molecular cloning, expression, and characterization of the cDNA for the rat hepatic squalene synthase.

PubMed ID: 1400448

DOI: 10.1016/s0021-9258(19)36619-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8509416

Title: Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence.

PubMed ID: 8509416

DOI: 10.1016/s0021-9258(18)31462-5

PubMed ID: 9575210

Title: Function-structure studies and identification of three enzyme domains involved in the catalytic activity in rat hepatic squalene synthase.

PubMed ID: 9575210

DOI: 10.1074/jbc.273.20.12515

PubMed ID: 16440058

Title: Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat.

PubMed ID: 16440058

DOI: 10.1172/jci20797

Sequence Information:

  • Length: 416
  • Mass: 48106
  • Checksum: F4BC4D09C9F72169
  • Sequence:
    • MEFVKCLGHP EEFYNLLRFR MGGRRNFIPK MDRNSLSNSL KTCYKYLDQT SRSFAAVIQA 
LDGDIRHAVC VFYLILRAMD TVEDDMAISV EKKIPLLRNF HTFLYEPEWR FTESKEKHRV 
VLEDFPTISL EFRNLAEKYQ TVIADICHRM GCGMAEFLNK DVTSKQDWDK YCHYVAGLVG 
IGLSRLFSAS EFEDPIVGED TECANSMGLF LQKTNIIRDY LEDQQEGRQF WPQEVWGKYV 
KKLEDFVKPE NVDVAVKCLN ELITNALQHI PDVITYLSRL RNQSVFNFCA IPQVMAIATL 
AACYNNHQVF KGVVKIRKGQ AVTLMMDATN MPAVKAIIYQ YIEEIYHRVP NSDPSASKAK 
QLISNIRTQS LPNCQLISRS HYSPIYLSFI MLLAALSWQY LSTLSQVTED YVQREH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.