Htr2b | ENSRNOG00000017625 | NCBI 29581

Details for: Htr2b

Gene ID: 29581

Symbol: Htr2b

Ensembl ID: ENSRNOG00000017625

Description: 5-hydroxytryptamine receptor 2B

Associated with

Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Serotonin receptors
(R-RNO-390666)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Calcium-mediated signaling
(GO:0019722)
Cardiac muscle hypertrophy
(GO:0003300)
Cellular response to amine stimulus
(GO:0071418)
Cellular response to serotonin
(GO:1904015)
Cellular response to temperature stimulus
(GO:0071502)
Cgmp-mediated signaling
(GO:0019934)
Chemical synaptic transmission
(GO:0007268)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Embryonic morphogenesis
(GO:0048598)
Erk1 and erk2 cascade
(GO:0070371)
G-protein alpha-subunit binding
(GO:0001965)
G protein-coupled receptor internalization
(GO:0002031)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
G protein-coupled serotonin receptor complex
(GO:0098666)
G protein-coupled serotonin receptor signaling pathway
(GO:0098664)
Gq/11-coupled serotonin receptor activity
(GO:0001587)
Gtpase activator activity
(GO:0005096)
Heart development
(GO:0007507)
Heart morphogenesis
(GO:0003007)
Hepatic stellate cell activation
(GO:0035733)
Inositol phosphate metabolic process
(GO:0043647)
Intestine smooth muscle contraction
(GO:0014827)
Intracellular calcium ion homeostasis
(GO:0006874)
Monoatomic ion transmembrane transport
(GO:0034220)
Negative regulation of apoptotic process
(GO:0043066)
Neural crest cell differentiation
(GO:0014033)
Neural crest cell migration
(GO:0001755)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Neurotransmitter receptor activity
(GO:0030594)
Nucleoplasm
(GO:0005654)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Phospholipase c-activating serotonin receptor signaling pathway
(GO:0007208)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of phosphatidylinositol biosynthetic process
(GO:0010513)
Protein binding
(GO:0005515)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Protein kinase c signaling
(GO:0070528)
Regulation of behavior
(GO:0050795)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to xenobiotic stimulus
(GO:0009410)
Serotonin binding
(GO:0051378)
Synapse
(GO:0045202)
Vasoconstriction
(GO:0042310)

Other Information

Proteins

5-hydroxytryptamine receptor 2B

Genular Protein ID: 3045896775

Symbol: 5HT2B_RAT

Name: 5-hydroxytryptamine receptor 2B

UniProtKB Accession Codes:

P30994 Q9QW44

Database IDs:

Citations:

PubMed ID: 1505525

Title: Cloning and functional characterization of the rat stomach fundus serotonin receptor.

PubMed ID: 1505525

DOI: 10.1002/j.1460-2075.1992.tb05427.x

PubMed ID: 1331748

Title: Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus.

PubMed ID: 1331748

PubMed ID: 22525520

Title: Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.

PubMed ID: 22525520

DOI: 10.1016/j.pain.2012.03.024

Sequence Information:

Length: 479
Mass: 53652
Checksum: 17FFC73213B42038
Sequence:

MASSYKMSEQ STISEHILQK TCDHLILTDR SGLKAESAAE EMKQTAENQG NTVHWAALLI 
FAVIIPTIGG NILVILAVSL EKRLQYATNY FLMSLAVADL LVGLFVMPIA LLTIMFEATW 
PLPLALCPAW LFLDVLFSTA SIMHLCAISL DRYIAIKKPI QANQCNSRTT AFVKITVVWL 
ISIGIAIPVP IKGIEADVVN AHNITCELTK DRFGSFMLFG SLAAFFAPLT IMIVTYFLTI 
HALRKKAYLV RNRPPQRLTR WTVSTVLQRE DSSFSSPEKM VMLDGSHKDK ILPNSTDETL 
MRRMSSAGKK PAQTISNEQR ASKVLGIVFL FFLLMWCPFF ITNVTLALCD SCNQTTLKTL 
LQIFVWVGYV SSGVNPLIYT LFNKTFREAF GRYITCNYQA TKSVKVLRKC SSTLYFGNSM 
VENSKFFTKH GIRNGINPAM YQSPVRLRSS TIQSSSIILL NTFLTENDGD KVEDQVSYI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.