Tgfbr1 | ENSRNOG00000007036 | NCBI 29591

Details for: Tgfbr1

Gene ID: 29591

Symbol: Tgfbr1

Ensembl ID: ENSRNOG00000007036

Description: transforming growth factor, beta receptor 1

Associated with

Deubiquitination
(R-RNO-5688426)
Downregulation of tgf-beta receptor signaling
(R-RNO-2173788)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Tgf-beta receptor signaling activates smads
(R-RNO-2173789)
Tgf-beta receptor signaling in emt (epithelial to mesenchymal transition)
(R-RNO-2173791)
Ub-specific processing proteases
(R-RNO-5689880)
Activin binding
(GO:0048185)
Activin receptor activity, type i
(GO:0016361)
Activin receptor signaling pathway
(GO:0032924)
Angiogenesis
(GO:0001525)
Animal organ regeneration
(GO:0031100)
Anterior/posterior pattern specification
(GO:0009952)
Apoptotic process
(GO:0006915)
Artery morphogenesis
(GO:0048844)
Atp binding
(GO:0005524)
Blastocyst development
(GO:0001824)
Cell motility
(GO:0048870)
Collagen fibril organization
(GO:0030199)
Digestive tract development
(GO:0048565)
Embryo implantation
(GO:0007566)
Embryonic cranial skeleton morphogenesis
(GO:0048701)
Endothelial cell activation
(GO:0042118)
Endothelial cell migration
(GO:0043542)
Endothelial cell proliferation
(GO:0001935)
Epithelial to mesenchymal transition
(GO:0001837)
Filopodium assembly
(GO:0046847)
Germ cell migration
(GO:0008354)
Growth factor binding
(GO:0019838)
Heart development
(GO:0007507)
I-smad binding
(GO:0070411)
Intracellular signal transduction
(GO:0035556)
In utero embryonic development
(GO:0001701)
Kidney development
(GO:0001822)
Lens development in camera-type eye
(GO:0002088)
Lung development
(GO:0030324)
Male gonad development
(GO:0008584)
Mesenchymal cell differentiation
(GO:0048762)
Metal ion binding
(GO:0046872)
Myofibroblast differentiation
(GO:0036446)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of chondrocyte differentiation
(GO:0032331)
Negative regulation of endothelial cell differentiation
(GO:0045602)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Nervous system development
(GO:0007399)
Neuron fate commitment
(GO:0048663)
Phosphorylation
(GO:0016310)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of filopodium assembly
(GO:0051491)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of stress fiber assembly
(GO:0051496)
Post-embryonic development
(GO:0009791)
Proepicardium development
(GO:0003342)
Protein-containing complex binding
(GO:0044877)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of epithelial to mesenchymal transition
(GO:0010717)
Regulation of gene expression
(GO:0010468)
Regulation of protein ubiquitination
(GO:0031396)
Response to electrical stimulus
(GO:0051602)
Response to estrogen
(GO:0043627)
Response to hypoxia
(GO:0001666)
Response to organic cyclic compound
(GO:0014070)
Response to prostaglandin e
(GO:0034695)
Response to toxic substance
(GO:0009636)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Skeletal system development
(GO:0001501)
Skeletal system morphogenesis
(GO:0048705)
Smad binding
(GO:0046332)
Thymus development
(GO:0048538)
Transforming growth factor beta binding
(GO:0050431)
Transforming growth factor beta receptor activity
(GO:0005024)
Transforming growth factor beta receptor activity, type i
(GO:0005025)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Transmembrane receptor protein serine/threonine kinase activity
(GO:0004675)
Type ii transforming growth factor beta receptor binding
(GO:0005114)
Ubiquitin protein ligase binding
(GO:0031625)
Ventricular compact myocardium morphogenesis
(GO:0003223)
Ventricular trabecula myocardium morphogenesis
(GO:0003222)

Other Information

Proteins

TGF-beta receptor type-1
Q5M9H3_RAT

Genular Protein ID: 2552738208

Symbol: TGFR1_RAT

Name: TGF-beta receptor type-1

UniProtKB Accession Codes:

P80204

Database IDs:

Citations:

PubMed ID: 8395914

Title: Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth factor-beta type II receptor family.

PubMed ID: 8395914

DOI: 10.1002/aja.1001960207

PubMed ID: 8756725

Title: The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

PubMed ID: 8756725

DOI: 10.1016/s0092-8674(00)80116-6

PubMed ID: 18469808

Title: The type I TGF-beta receptor is covalently modified and regulated by sumoylation.

PubMed ID: 18469808

DOI: 10.1038/ncb1728

Sequence Information:

Length: 501
Mass: 56000
Checksum: EAD7F8D37E456102
Sequence:

MEAASAALRR CLLLIVLVAA ATLLPGAKAL QCFCHLCTKD NFTCETDGLC FVSVTETTDK 
VIHNSMCIAE IDLIPRDRPF VCAPSSKTGA VTYCCNQDHC NKIELPTTGP FSEKQSAGLG 
PVELAAVIAG PVCFVCIALM LMVYICHNRT VIHHRVPNEE DPSLDRPFIS EGTTLKDLIY 
DMTTSGSGSG LPLLVQRTIA RTIVLQESIG KGRFGEVWRG KWRGEEVAVK IFSSREERSW 
FREAEIYQTV MLRHENILGF IAADNKDNGT WTQLWLVSDY HEHGSLFDYL NRYTVTVEGM 
IKLALSTASG LAHLHMEIVG TQGKPAIAHR DLKSKNILVK KNGTCCIADL GLAVRHDSAT 
DTIDIAPNHR VGTKRYMAPE VLDDSINMKH FESFKRADIY AMGLVFWEIA RRCSIGGIHE 
DYQLPYYDLV PSDPSVEEMR KVVCEQKLRP NIPNRWQSCE ALRVMAKIMR ECWYANGAAR 
LTALRIKKTL SQLSQQEGIK M

Genular Protein ID: 2528373983

Symbol: Q5M9H3_RAT

Name: N/A

UniProtKB Accession Codes:

Q5M9H3

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 497
Mass: 55611
Checksum: F91F148E077DB225
Sequence:

MEAASAALRR CLLLIVLVAA ATLLPGAKAL QCFCHLCTKD NFTCETDGLC FVSVTETTDK 
VIHNSMCIAE IDLIPRDRPF VCAPSSKTGA VTYCCNQDHC NKIELPTTEK QSAGLGPVEL 
AAVIAGPVCF VCIALMLMVY ICHNRTVIHH RVPNEEDPSL DRPFISEGTT LKDLIYDMTT 
SGSGSGLPLL VQRTIARTIV LQESIGKGRF GEVWRGKWRG EEVAVKIFSS REERSWFREA 
EIYQTVMLRH ENILGFIAAD NKDNGTWTQL WLVSDYHEHG SLFDYLNRYT VTVEGMIKLA 
LSTASGLAHL HMEIVGTQGK PAIAHRDLKS KNILVKKNGT CCIADLGLAV RHDSATDTID 
IAPNHRVGTK RYMAPEVLDD SINMKHFESF KRADIYAMGL VFWEIARRCS IGGIHEDYQL 
PYYDLVPSDP SVEEMRKVVC EQKLRPNIPN RWQSCEALRV MAKIMRECWY ANGAARLTAL 
RIKKTLSQLS QQEGIKM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tgfbr1

Associated with

Other Information

Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth factor-beta type II receptor family. PubMed ID: 8395914

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors. PubMed ID: 8756725

The type I TGF-beta receptor is covalently modified and regulated by sumoylation. PubMed ID: 18469808

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 8395914

PubMed ID: 8756725

PubMed ID: 18469808

PubMed ID: 15489334