Htr2a | ENSRNOG00000010063 | NCBI 29595

Details for: Htr2a

Gene ID: 29595

Symbol: Htr2a

Ensembl ID: ENSRNOG00000010063

Description: 5-hydroxytryptamine receptor 2A

Associated with

Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Serotonin receptors
(R-RNO-390666)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
(GO:0071886)
Artery smooth muscle contraction
(GO:0014824)
Axon
(GO:0030424)
Behavioral response to cocaine
(GO:0048148)
Caveola
(GO:0005901)
Cell body fiber
(GO:0070852)
Chemical synaptic transmission
(GO:0007268)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Dendritic shaft
(GO:0043198)
Detection of mechanical stimulus involved in sensory perception of pain
(GO:0050966)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Glutamatergic synapse
(GO:0098978)
Glycolytic process
(GO:0006096)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
G protein-coupled serotonin receptor complex
(GO:0098666)
G protein-coupled serotonin receptor signaling pathway
(GO:0098664)
Gq/11-coupled serotonin receptor activity
(GO:0001587)
Identical protein binding
(GO:0042802)
Intracellular calcium ion homeostasis
(GO:0006874)
Memory
(GO:0007613)
Negative regulation of potassium ion transport
(GO:0043267)
Negative regulation of synaptic transmission, glutamatergic
(GO:0051967)
Neurofilament
(GO:0005883)
Neuronal cell body
(GO:0043025)
Neurotransmitter receptor activity
(GO:0030594)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Phospholipase c-activating serotonin receptor signaling pathway
(GO:0007208)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytokine production involved in immune response
(GO:0002720)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of dna biosynthetic process
(GO:2000573)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of execution phase of apoptosis
(GO:1900119)
Positive regulation of fat cell differentiation
(GO:0045600)
Positive regulation of glycolytic process
(GO:0045821)
Positive regulation of heat generation
(GO:0031652)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of phosphatidylinositol biosynthetic process
(GO:0010513)
Positive regulation of platelet aggregation
(GO:1901731)
Positive regulation of vasoconstriction
(GO:0045907)
Postsynaptic membrane
(GO:0045211)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization to cytoskeleton
(GO:0044380)
Protein tyrosine kinase activator activity
(GO:0030296)
Regulation of dopamine secretion
(GO:0014059)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to cocaine
(GO:0042220)
Response to xenobiotic stimulus
(GO:0009410)
Sensitization
(GO:0046960)
Sensory perception of temperature stimulus
(GO:0050951)
Serotonin binding
(GO:0051378)
Temperature homeostasis
(GO:0001659)
Urinary bladder smooth muscle contraction
(GO:0014832)

Other Information

Proteins

5-hydroxytryptamine receptor 2A

Genular Protein ID: 845468070

Symbol: 5HT2A_RAT

Name: 5-hydroxytryptamine receptor 2A

UniProtKB Accession Codes:

P14842

Database IDs:

Citations:

PubMed ID: 2300586

Title: The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.

PubMed ID: 2300586

DOI: 10.1073/pnas.87.3.928

PubMed ID: 2854054

Title: Structure and functional expression of cloned rat serotonin 5HT-2 receptor.

PubMed ID: 2854054

DOI: 10.1002/j.1460-2075.1988.tb03308.x

PubMed ID: 1765383

Title: The 5-HT2 serotonin receptor gene Htr-2 is tightly linked to Es-10 on mouse chromosome 14.

PubMed ID: 1765383

DOI: 10.1016/0888-7543(91)90127-z

PubMed ID: 11960784

Title: 5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice.

PubMed ID: 11960784

DOI: 10.1152/ajpgi.00435.2001

Sequence Information:

Length: 471
Mass: 52850
Checksum: 3626DACE5F6C7FF4
Sequence:

MEILCEDNIS LSSIPNSLMQ LGDGPRLYHN DFNSRDANTS EASNWTIDAE NRTNLSCEGY 
LPPTCLSILH LQEKNWSALL TTVVIILTIA GNILVIMAVS LEKKLQNATN YFLMSLAIAD 
MLLGFLVMPV SMLTILYGYR WPLPSKLCAI WIYLDVLFST ASIMHLCAIS LDRYVAIQNP 
IHHSRFNSRT KAFLKIIAVW TISVGISMPI PVFGLQDDSK VFKEGSCLLA DDNFVLIGSF 
VAFFIPLTIM VITYFLTIKS LQKEATLCVS DLSTRAKLAS FSFLPQSSLS SEKLFQRSIH 
REPGSYAGRR TMQSISNEQK ACKVLGIVFF LFVVMWCPFF ITNIMAVICK ESCNENVIGA 
LLNVFVWIGY LSSAVNPLVY TLFNKTYRSA FSRYIQCQYK ENRKPLQLIL VNTIPALAYK 
SSQLQVGQKK NSQEDAEQTV DDCSMVTLGK QQSEENCTDN IETVNEKVSC V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Htr2a

Associated with

Other Information

The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors. PubMed ID: 2300586

Structure and functional expression of cloned rat serotonin 5HT-2 receptor. PubMed ID: 2854054

The 5-HT2 serotonin receptor gene Htr-2 is tightly linked to Es-10 on mouse chromosome 14. PubMed ID: 1765383

5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice. PubMed ID: 11960784

Database document:

PubMed ID: 2300586

PubMed ID: 2854054

PubMed ID: 1765383

PubMed ID: 11960784