Bckdk | ENSRNOG00000019485 | NCBI 29603

Details for: Bckdk

Gene ID: 29603

Symbol: Bckdk

Ensembl ID: ENSRNOG00000019485

Description: branched chain ketoacid dehydrogenase kinase

Associated with

Branched-chain amino acid catabolism
(R-RNO-70895)
Chromatin modifying enzymes
(R-RNO-3247509)
Chromatin organization
(R-RNO-4839726)
Epigenetic regulation of gene expression
(R-RNO-212165)
Formation of wdr5-containing histone-modifying complexes
(R-RNO-9772755)
Gene expression (transcription)
(R-RNO-74160)
Hats acetylate histones
(R-RNO-3214847)
Metabolism
(R-RNO-1430728)
Metabolism of amino acids and derivatives
(R-RNO-71291)
Atp binding
(GO:0005524)
Branched-chain amino acid catabolic process
(GO:0009083)
Chromatin remodeling
(GO:0006338)
Chromosome
(GO:0005694)
Enzyme binding
(GO:0019899)
Histone acetyltransferase activity
(GO:0004402)
Histone h4k5 acetyltransferase activity
(GO:0043995)
Histone h4k8 acetyltransferase activity
(GO:0043996)
Histone h4k16 acetyltransferase activity
(GO:0046972)
Isoleucine catabolic process
(GO:0006550)
Kinetochore
(GO:0000776)
Leucine catabolic process
(GO:0006552)
Lipid biosynthetic process
(GO:0008610)
Metal ion binding
(GO:0046872)
Mitochondrial alpha-ketoglutarate dehydrogenase complex
(GO:0005947)
Mitochondrion
(GO:0005739)
Mll1 complex
(GO:0071339)
Msl complex
(GO:0072487)
Myeloid cell differentiation
(GO:0030099)
Negative regulation of dna-templated transcription
(GO:0045892)
Neurogenesis
(GO:0022008)
Nsl complex
(GO:0044545)
Nuclear matrix
(GO:0016363)
Nucleus
(GO:0005634)
Phosphorylation
(GO:0016310)
Positive regulation of dna-templated transcription
(GO:0045893)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine/threonine phosphatase activity
(GO:0004722)
Protein serine kinase activity
(GO:0106310)
Pyruvate dehydrogenase (acetyl-transferring) kinase activity
(GO:0004740)
Regulation of autophagy
(GO:0010506)
Regulation of glucose metabolic process
(GO:0010906)
Regulation of mrna processing
(GO:0050684)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Spermatogenesis
(GO:0007283)
Transcription coactivator activity
(GO:0003713)
Transcription initiation-coupled chromatin remodeling
(GO:0045815)
Valine catabolic process
(GO:0006574)
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity
(GO:0047323)

Other Information

Proteins

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

Genular Protein ID: 3402189120

Symbol: BCKD_RAT

Name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

UniProtKB Accession Codes:

Q00972 Q64552

Database IDs:

Citations:

PubMed ID: 1377677

Title: Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases.

PubMed ID: 1377677

DOI: 10.1016/s0021-9258(18)42179-5

PubMed ID: 1496922

Title: Purification, characterization, regulation and molecular cloning of mitochondrial protein kinases.

PubMed ID: 1496922

DOI: 10.1016/0065-2571(92)90022-r

PubMed ID: 7649998

Title: Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?

PubMed ID: 7649998

DOI: 10.1074/jbc.270.34.19861

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 29779826

Title: The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

PubMed ID: 29779826

DOI: 10.1016/j.cmet.2018.04.015

PubMed ID: 11562470

Title: Structure of rat BCKD kinase: nucleotide-induced domain communication in a mitochondrial protein kinase.

PubMed ID: 11562470

DOI: 10.1073/pnas.201220098

Sequence Information:

Length: 412
Mass: 46474
Checksum: D630D3A44728927E
Sequence:

MILTSVLGSG PRSGSSLWPL LGSSLSLRVR STSATDTHHV ELARERSKTV TSFYNQSAID 
VVAEKPSVRL TPTMMLYSGR SQDGSHLLKS GRYLQQELPV RIAHRIKGFR SLPFIIGCNP 
TILHVHELYI RAFQKLTDFP PIKDQADEAQ YCQLVRQLLD DHKDVVTLLA EGLRESRKHI 
EDEKLVRYFL DKTLTSRLGI RMLATHHLAL HEDKPDFVGI ICTRLSPKKI IEKWVDFARR 
LCEHKYGNAP RVRINGHVAA RFPFIPMPLD YILPELLKNA MRATMESHLD TPYNVPDVVI 
TIANNDVDLI IRISDRGGGI AHKDLDRVMD YHFTTAEAST QDPRISPLFG HLDMHSGGQS 
GPMHGFGFGL PTSRAYAEYL GGSLQLQSLQ GIGTDVYLRL RHIDGREESF RI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bckdk

Associated with

Other Information

Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases. PubMed ID: 1377677

Purification, characterization, regulation and molecular cloning of mitochondrial protein kinases. PubMed ID: 1496922

Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase? PubMed ID: 7649998

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase. PubMed ID: 29779826