Details for: Pitx3

Gene ID: 29609

Symbol: Pitx3

Ensembl ID: ENSRNOG00000019194

Description: paired-like homeodomain 3

Associated with

  • Anatomical structure morphogenesis
    (GO:0009653)
  • Cellular response to glial cell derived neurotrophic factor
    (GO:1990792)
  • Chromatin
    (GO:0000785)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dopaminergic neuron differentiation
    (GO:0071542)
  • Lens development in camera-type eye
    (GO:0002088)
  • Lens fiber cell differentiation
    (GO:0070306)
  • Lens morphogenesis in camera-type eye
    (GO:0002089)
  • Locomotory behavior
    (GO:0007626)
  • Midbrain development
    (GO:0030901)
  • Negative regulation of gliogenesis
    (GO:0014014)
  • Negative regulation of neurogenesis
    (GO:0050768)
  • Neuron development
    (GO:0048666)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cell proliferation in midbrain
    (GO:1904935)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of neuron apoptotic process
    (GO:0043525)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of gene expression
    (GO:0010468)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to cocaine
    (GO:0042220)
  • Response to immobilization stress
    (GO:0035902)
  • Response to methamphetamine hydrochloride
    (GO:1904313)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 1026954182

Symbol: PITX3_RAT

Name: Pituitary homeobox 3

UniProtKB Accession Codes:

P81062

Database IDs:

AGR 1 AlphaFoldDB 1 BMRB 1 Bgee 1 CDD 1 CTD 1 DNASU 1 EMBL 1 Ensembl 4 GO 28 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9371841

Title: A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons.

PubMed ID: 9371841

DOI: 10.1073/pnas.94.24.13305

PubMed ID: 16641100

Title: Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.

PubMed ID: 16641100

DOI: 10.1073/pnas.0600895103

PubMed ID: 18951485

Title: Immunocytochemical expression of dopamine-related transcription factors Pitx3 and Nurr1 in prenatally stressed adult rats.

PubMed ID: 18951485

DOI: 10.1002/jnr.21911

Sequence Information:

  • Length: 302
  • Mass: 31729
  • Checksum: DE0E81863C44E714
  • Sequence:
    • MEFGLLGEAE ARSPALSLSD AGTPHPPLPE HGCKGQEHSD SEKASASLPG GSPEDGSLKK 
KQRRQRTHFT SQQLQELEAT FQRNRYPDMS TREEIAVWTN LTEARVRVWF KNRRAKWRKR 
ERSQQAELCK GGFAAPLGGL VPPYEEVYPG YTYGNWPPKA LAPPLAAKTF PFAFNSVNVG 
PLASQPVFSP PSSIAASMVP SAAAAPGTVP GPGALQGLGG APPGLAPAAV SSGAVSCPYA 
SAAAAAAAAA SSPYVYRDPC NSSLASLRLK AKQHASFSYP AVPGPPPAAN LSPCQYAVER 
PV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.