Ndst1 | ENSRNOG00000019014 | NCBI 29633

Details for: Ndst1

Gene ID: 29633

Symbol: Ndst1

Ensembl ID: ENSRNOG00000019014

Description: N-deacetylase and N-sulfotransferase 1

Associated with

Glycosaminoglycan metabolism
(R-RNO-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-RNO-1638091)
Hs-gag biosynthesis
(R-RNO-2022928)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Animal organ morphogenesis
(GO:0009887)
Aorta development
(GO:0035904)
Cardiac septum development
(GO:0003279)
Cell population proliferation
(GO:0008283)
Coronary vasculature development
(GO:0060976)
Deacetylase activity
(GO:0019213)
Embryonic neurocranium morphogenesis
(GO:0048702)
Embryonic viscerocranium morphogenesis
(GO:0048703)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Forebrain development
(GO:0030900)
Glycosaminoglycan metabolic process
(GO:0030203)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Heart development
(GO:0007507)
Heparan sulfate n-deacetylase activity
(GO:0102140)
Heparan sulfate proteoglycan biosynthetic process
(GO:0015012)
Heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
(GO:0015014)
Heparin biosynthetic process
(GO:0030210)
Inflammatory response
(GO:0006954)
Midbrain development
(GO:0030901)
N-acetylglucosamine deacetylase activity
(GO:0050119)
Polysaccharide biosynthetic process
(GO:0000271)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of smoothened signaling pathway
(GO:0045880)
Respiratory gaseous exchange by respiratory system
(GO:0007585)
Sulfotransferase activity
(GO:0008146)
Trans-golgi network membrane
(GO:0032588)
[heparan sulfate]-glucosamine n-sulfotransferase activity
(GO:0015016)

Other Information

Proteins

Glucosaminyl N-deacetylase/N-sulfotransferase 1

Genular Protein ID: 3504157514

Symbol: NDST1_RAT

Name: Glucosaminyl N-deacetylase/N-sulfotransferase 1

UniProtKB Accession Codes:

Q02353

Database IDs:

Citations:

PubMed ID: 1379236

Title: Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase.

PubMed ID: 1379236

DOI: 10.1016/s0021-9258(19)49598-7

PubMed ID: 3422231

Title: Purification of rat liver N-heparan-sulfate sulfotransferase.

PubMed ID: 3422231

DOI: 10.1016/s0021-9258(18)69223-3

PubMed ID: 8483907

Title: A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate.

PubMed ID: 8483907

DOI: 10.1073/pnas.90.9.3885

PubMed ID: 9890952

Title: Functional analysis of conserved cysteines in heparan sulfate N-deacetylase-N-sulfotransferases.

PubMed ID: 9890952

DOI: 10.1074/jbc.274.4.1966

PubMed ID: 11792394

Title: Immunopurification of Golgi vesicles by magnetic sorting.

PubMed ID: 11792394

DOI: 10.1016/s0022-1759(01)00546-4

Sequence Information:

Length: 882
Mass: 100785
Checksum: F3AB9263EF6E4345
Sequence:

MPALACLRRL CRHLSPQAVL FLLFVFCLFS VFVSAYYLYG WNRGLEPSAD ASESDCGDPP 
PVAPSRLLPI KPVQAVAPSR TDPLVLVFVE SLYSQLGQEV VAILESSRFK YRTEIAPGKG 
DMPTLTDKGR GRFALIIYEN ILKYVNLDAW NRELLDKYCV AYGVGIIGFF KANENSLLSA 
QLKGFPLFLH SNLGLKDCSI NPKSPLLYVT RPSEVEKGVL PGEDWTVFQS NHSTYEPVLL 
AKTRSSESIP HLGADAGLHA ALHATVVQDL GLHDGIQRVL FGNNLNFWLH KLVFVDAVAF 
LTGKRLSLPL DRYILVDIDD IFVGKEGTRM KVEDVKALFD TQNELRTHIP NFTFNLGYSG 
KFFHTGTDAE DAGDDLLLSY VKEFWWFPHM WSHMQPHLFH NQSVLAEQMA LNKKFAVEHG 
IPTDMGYAVA PHHSGVYPVH VQLYEAWKQV WNIRVTSTEE YPHLKPARYR RGFIHNGIMV 
LPRQTCGLFT HTIFYNEYPG GSSELDKIIN GGELFLTVLL NPISVFMTHL SNYGNDRLGL 
YTFKHLVRFL HSWTNLRLQT LPPVQLAQKY FQIFSEEKDP LWQDPCEDKR HKDIWSKEKT 
CDRFPKLLII GPQKTGTTAL YLFLGMHPDL SSNYPSSETF EEIQFFNGHN YHKGIDWYME 
FFPIPSNTTS DFYFEKSANY FDSEVAPRRA AALLPKAKVL TILINPADRA YSWYQHQRAH 
DDPVALKYTF HEVITAGPDA SSKLRALQNR CLVPGWYATH IERWLSAFHA NQILVLDGKL 
LRTEPAKVMD TVQKFLGVTS TVDYHKTLAF DPKKGFWCQL LEGGKTKCLG KSKGRKYPEM 
DLDSRAFLKD YYRDHNIELS KLLYKMGQTL PTWLREDLQN TR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ndst1

Associated with

Other Information

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase. PubMed ID: 1379236

Purification of rat liver N-heparan-sulfate sulfotransferase. PubMed ID: 3422231

A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate. PubMed ID: 8483907