Details for: Dpm2

Gene ID: 29640

Symbol: Dpm2

Ensembl ID: ENSRNOG00000070298

Description: dolichyl-phosphate mannosyltransferase subunit 2, regulatory

Associated with

  • Asparagine n-linked glycosylation
    (R-RNO-446203)
  • Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
    (R-RNO-446193)
  • Metabolism of proteins
    (R-RNO-392499)
  • Post-translational modification: synthesis of gpi-anchored proteins
    (R-RNO-163125)
  • Post-translational protein modification
    (R-RNO-597592)
  • Synthesis of dolichyl-phosphate mannose
    (R-RNO-162699)
  • Synthesis of glycosylphosphatidylinositol (gpi)
    (R-RNO-162710)
  • Synthesis of substrates in n-glycan biosythesis
    (R-RNO-446219)
  • Dolichol-phosphate-mannose synthase complex
    (GO:0033185)
  • Dolichol metabolic process
    (GO:0019348)
  • Dolichyl-phosphate beta-d-mannosyltransferase activity
    (GO:0004582)
  • Endoplasmic reticulum
    (GO:0005783)
  • Endoplasmic reticulum membrane
    (GO:0005789)
  • Enzyme activator activity
    (GO:0008047)
  • Enzyme regulator activity
    (GO:0030234)
  • Glycosylphosphatidylinositol-n-acetylglucosaminyltransferase (gpi-gnt) complex
    (GO:0000506)
  • Gpi anchor biosynthetic process
    (GO:0006506)
  • Perinuclear region of cytoplasm
    (GO:0048471)
  • Protein binding
    (GO:0005515)
  • Protein glycosylation
    (GO:0006486)
  • Regulation of protein stability
    (GO:0031647)

Other Information

Genular Protein ID: 893742625

Symbol: DPM2_RAT

Name: Dolichol-phosphate mannose synthase subunit 2

UniProtKB Accession Codes:

Q9Z325

Database IDs:

AGR 1 AlphaFoldDB 1 CTD 1 EMBL 1 GO 12 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RGD 2 Reactome 2 RefSeq 1 SMR 1 STRING 1 UniPathway 1 UniProtKB 1 eggNOG 1

Citations:

PubMed ID: 9724629

Title: DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.

PubMed ID: 9724629

DOI: 10.1093/emboj/17.17.4920

Sequence Information:

  • Length: 84
  • Mass: 9344
  • Checksum: 345C9AC265573300
  • Sequence:
    • MATGTDQAVG FGLVAVSLII FTYYTTWVIL LPFIDSQHVI HKYFLPRAYA VLLPLAAGLL 
LLLFVGLFIT YVLLKSQKVT KKAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.