Details for: Slc38a2

Gene ID: 29642

Symbol: Slc38a2

Ensembl ID: ENSRNOG00000006305

Description: solute carrier family 38, member 2

Associated with

Other Information

Genular Protein ID: 4122590608

Symbol: S38A2_RAT

Name: Sodium-coupled neutral amino acid symporter 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10747860

Title: Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A.

PubMed ID: 10747860

DOI: 10.1074/jbc.c000205200

PubMed ID: 10811809

Title: A novel system A isoform mediating Na+/neutral amino acid cotransport.

PubMed ID: 10811809

DOI: 10.1074/jbc.m002965200

PubMed ID: 10859363

Title: Amino acid transport system A resembles system N in sequence but differs in mechanism.

PubMed ID: 10859363

DOI: 10.1073/pnas.140152797

PubMed ID: 11311116

Title: Subcellular localization and adaptive up-regulation of the system A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes.

PubMed ID: 11311116

DOI: 10.1042/bj3550563

PubMed ID: 11716780

Title: Transforming growth factor-beta 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression.

PubMed ID: 11716780

DOI: 10.1042/0264-6021:3600507

PubMed ID: 12054432

Title: ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane.

PubMed ID: 12054432

DOI: 10.1016/s0003-9861(02)00006-1

PubMed ID: 11834730

Title: Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells.

PubMed ID: 11834730

DOI: 10.1074/jbc.m108609200

PubMed ID: 11756489

Title: Glutamine uptake by neurons: interaction of protons with system a transporters.

PubMed ID: 11756489

DOI: 10.1523/jneurosci.22-01-00062.2002

PubMed ID: 12021389

Title: ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline.

PubMed ID: 12021389

DOI: 10.1124/mol.61.6.1289

PubMed ID: 15561425

Title: Immunohistochemical localization of the amino acid transporter SNAT2 in the rat brain.

PubMed ID: 15561425

DOI: 10.1016/j.neuroscience.2004.09.023

PubMed ID: 16629640

Title: Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue.

PubMed ID: 16629640

DOI: 10.1042/bj20060026

PubMed ID: 16616430

Title: Localization of the Na(+)-coupled neutral amino acid transporter 2 in the cerebral cortex.

PubMed ID: 16616430

DOI: 10.1016/j.neuroscience.2006.02.042

PubMed ID: 17488712

Title: Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability.

PubMed ID: 17488712

DOI: 10.1074/jbc.m611520200

PubMed ID: 18319257

Title: Highly conserved asparagine 82 controls the interaction of Na+ with the sodium-coupled neutral amino acid transporter SNAT2.

PubMed ID: 18319257

DOI: 10.1074/jbc.m706774200

PubMed ID: 18330498

Title: Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.

PubMed ID: 18330498

DOI: 10.1007/s00726-008-0050-9

PubMed ID: 19589777

Title: A conserved Na(+) binding site of the sodium-coupled neutral amino acid transporter 2 (SNAT2).

PubMed ID: 19589777

DOI: 10.1074/jbc.m109.038422

PubMed ID: 18832333

Title: System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate.

PubMed ID: 18832333

DOI: 10.1093/cercor/bhn151

PubMed ID: 21158741

Title: The C-terminal domain of the neutral amino acid transporter SNAT2 regulates transport activity through voltage-dependent processes.

PubMed ID: 21158741

DOI: 10.1042/bj20100507

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 27355203

Title: Identification of a disulfide bridge in sodium-coupled neutral amino acid transporter 2(SNAT2) by chemical modification.

PubMed ID: 27355203

DOI: 10.1371/journal.pone.0158319

PubMed ID: 29678469

Title: Membrane topology of rat sodium-coupled neutral amino acid transporter 2 (SNAT2).

PubMed ID: 29678469

DOI: 10.1016/j.bbamem.2018.04.005

Sequence Information:

  • Length: 504
  • Mass: 55554
  • Checksum: F53022C07152648C
  • Sequence:
  • MKKTEMGRFN ISPDEDSSSY SSNGDFNYSY PTKQAALKSH YVDVDPENQN FLLESNLGKK 
    KYETDFHPGT TSFGMSVFNL SNAIVGSGIL GLSYAMANTG IALFIILLTF VSIFSLYSVH 
    LLLKTANEGG SLLYEQLGHK AYGLAGKLAA SGSITMQNIG AMSSYLFIVK YELPLVIKAL 
    MNIEDTNGLW YLNGDYLVLL VSFVLILPLS LLRNLGYLGY TSGLSLLCMI FFLIVVICKK 
    FQIPCPVEVA LMANETVNGT FTQVALAALA SNSTAADTCR PRYFIFNSQT VYAVPILTFS 
    FVCHPAVLPI YEELKSRSRR RMMNVSKISF FAMFLMYLLA ALFGYLTFYE HVESELLHTY 
    SAIVGTDILL LVVRLAVLVA VTLTVPVVIF PIRSSVTHLL CPTKEFSWFR HSVITVTILA 
    FTNLLVIFVP TIRDIFGFIG ASAAAMLIFI LPSAFYIKLV KKEPMRSVQK IGALCFLLSG 
    VVVMIGSMGL IVLDWVHDAS AGGH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.