Details for: Sv2c
Associated with
Other Information
Genular Protein ID: 3643326293
Symbol: SV2C_RAT
Name: Synaptic vesicle glycoprotein 2C
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9801366
Title: SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles.
PubMed ID: 9801366
PubMed ID: 10625067
Title: SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family.
PubMed ID: 10625067
PubMed ID: 16306227
Title: SV2A and SV2C are not vesicular Ca2+ transporters but control glucose-evoked granule recruitment.
PubMed ID: 16306227
DOI: 10.1242/jcs.02658
PubMed ID: 15866046
Title: SV2A and SV2C contain a unique synaptotagmin-binding site.
PubMed ID: 15866046
PubMed ID: 16543415
Title: SV2 is the protein receptor for botulinum neurotoxin A.
PubMed ID: 16543415
PubMed ID: 18815274
Title: Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
PubMed ID: 18815274
PubMed ID: 19476346
Title: Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
PubMed ID: 19476346
DOI: 10.1021/bi9002138
PubMed ID: 19650874
Title: Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
PubMed ID: 19650874
PubMed ID: 21483489
Title: Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
PubMed ID: 21483489
PubMed ID: 21632541
Title: Novel ganglioside-mediated entry of botulinum neurotoxin serotype D into neurons.
PubMed ID: 21632541
PubMed ID: 27294781
Title: N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
PubMed ID: 27294781
DOI: 10.1038/nsmb.3245
Sequence Information:
- Length: 727
- Mass: 82249
- Checksum: 4C154C69341D8DB7
- Sequence:
MEDSYKDRTS LMKGAKDIAK EVKKQTVKKV NQAVDRAQDE YTQRSYSRFQ DEDDDDDYYP PGETYSGEAN DDEGSSEATE GHDEEDEIYE GEYQGIPSTN QGKDSIVSVG QPKGDEYKDR RELESERRAD EEELAQQYEL IIQECGHGRF QWALFFVLGM ALMADGVEVF VVGFVLPSAE TDLCIPNSGS GWLGSIVYLG MMVGAFFWGG LADKVGRKQS LLICMSVNGF FAFLSSFVQG YGFFLLCRLL SGFGIGGAIP TVFSYFAEVL AREKRGEHLS WLCMFWMIGG IYASAMAWAI IPHYGWSFSM GSAYQFHSWR VFVIVCALPC VSSVVALTFM PESPRFLLEV GKHDEAWMIL KLIHDTNMRA RGQPEKVFTV NKIKTPKQID ELIEIESDTG TWYRRCFVRI RTELYGIWLT FMRCFNYPVR ENTIKLTIVW FTLSFGYYGL SVWFPDVIKH LQSDEYALLT RNVQKDKYAN FSINFTMENQ VHTGMEYDNG RFLGVKFKSV TFKDSVFKSC TFDDVTSVNT YFKNCTFIDT LFENTDFEPY KFIDSEFQNC SFLHNKTGCQ ITFDDDYSAY WIYFVNFLGT LAVLPGNIVS ALLMDRIGRL TMLGGSMVLS GISCFFLWFG TSESMMIGML CLYNGLTISA WNSLDVVTVE LYPTDRRATG FGFLNALCKA AAVLGNLIFG SLVSITKAIP ILLASTVLVC GGLVGLRLPD TRTQVLM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.