Adam10 | ENSRNOG00000054257 | NCBI 29650

Details for: Adam10

Gene ID: 29650

Symbol: Adam10

Ensembl ID: ENSRNOG00000054257

Description: ADAM metallopeptidase domain 10

Associated with

Degradation of the extracellular matrix
(R-RNO-1474228)
Extracellular matrix organization
(R-RNO-1474244)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Metabolism of proteins
(R-RNO-392499)
Neutrophil degranulation
(R-RNO-6798695)
Notch3 activation and transmission of signal to the nucleus
(R-RNO-9013507)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Signaling by notch
(R-RNO-157118)
Signaling by notch3
(R-RNO-9012852)
Signal transduction
(R-RNO-162582)
Adherens junction
(GO:0005912)
Adherens junction organization
(GO:0034332)
Amyloid-beta formation
(GO:0034205)
Amyloid precursor protein catabolic process
(GO:0042987)
Axon
(GO:0030424)
Cell surface
(GO:0009986)
Clathrin-coated vesicle
(GO:0030136)
Cochlea development
(GO:0090102)
Constitutive protein ectodomain proteolysis
(GO:0051089)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Dendritic spine
(GO:0043197)
Endopeptidase activity
(GO:0004175)
Epidermal growth factor receptor ligand maturation
(GO:0038004)
Glutamatergic synapse
(GO:0098978)
Golgi-associated vesicle
(GO:0005798)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Intracellular membrane-bounded organelle
(GO:0043231)
In utero embryonic development
(GO:0001701)
Membrane protein ectodomain proteolysis
(GO:0006509)
Metal ion binding
(GO:0046872)
Metallodipeptidase activity
(GO:0070573)
Metalloendopeptidase activity
(GO:0004222)
Metalloendopeptidase activity involved in amyloid precursor protein catabolic process
(GO:1902945)
Metallopeptidase activity
(GO:0008237)
Molecular adaptor activity
(GO:0060090)
Monocyte activation
(GO:0042117)
Negative regulation of cell adhesion
(GO:0007162)
Negative regulation of gene expression
(GO:0010629)
Neuronal cell body
(GO:0043025)
Notch signaling pathway
(GO:0007219)
Nucleus
(GO:0005634)
Perinuclear endoplasmic reticulum
(GO:0097038)
Plasma membrane
(GO:0005886)
Pore complex
(GO:0046930)
Pore complex assembly
(GO:0046931)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of t cell chemotaxis
(GO:0010820)
Postsynapse
(GO:0098794)
Postsynapse organization
(GO:0099173)
Postsynaptic density
(GO:0014069)
Postsynaptic membrane
(GO:0045211)
Protein catabolic process at postsynapse
(GO:0140249)
Protein homodimerization activity
(GO:0042803)
Protein kinase binding
(GO:0019901)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Regulation of cellular component organization
(GO:0051128)
Regulation of dendritic spine morphogenesis
(GO:0061001)
Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
(GO:0098696)
Regulation of notch signaling pathway
(GO:0008593)
Regulation of osteoclast differentiation
(GO:0045670)
Regulation of postsynapse organization
(GO:0099175)
Regulation of vasculature development
(GO:1901342)
Response to antineoplastic agent
(GO:0097327)
Response to tumor necrosis factor
(GO:0034612)
Sh3 domain binding
(GO:0017124)
Signaling receptor ligand precursor processing
(GO:0140448)
Spermatogenesis
(GO:0007283)
Synaptic membrane
(GO:0097060)
Synaptic vesicle
(GO:0008021)
Tetraspanin-enriched microdomain
(GO:0097197)
Toxin transport
(GO:1901998)
Trans-golgi network
(GO:0005802)

Other Information

Proteins

Disintegrin and metalloproteinase domain-containing protein 10

Genular Protein ID: 2532248023

Symbol: ADA10_RAT

Name: Disintegrin and metalloproteinase domain-containing protein 10

UniProtKB Accession Codes:

Q10743 A0A0G2K562

Database IDs:

Citations:

PubMed ID: 8694785

Title: Molecular cloning of MADM: a catalytically active mammalian disintegrin-metalloprotease expressed in various cell types.

PubMed ID: 8694785

DOI: 10.1042/bj3170045

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 24090084

Title: Site-specific glycan-peptide analysis for determination of N-glycoproteome heterogeneity.

PubMed ID: 24090084

DOI: 10.1021/pr400783j

Sequence Information:

Length: 749
Mass: 84087
Checksum: 7E506394D93A3095
Sequence:

MVLPTVLILL LSWAAGLGGQ YGNPLNKYIR HYEGLSYNVD SLHQKHQRAK RAVSHEDQFL 
LLDFHAHGRQ FNLRMKRDTS LFSDEFKVET SNKVLDYDTS HIYTGHIYGE EGSFSHGSVV 
DGRFEGFIQT RGGTFYIEPA ERYIKDRILP FHSVIYHEDD INYPHKYGPQ GGCADHSVFE 
RMRKYQMTGV EEGTRAHSEE HAASMGPELL RKKRTTLAER NTCQLYIQTD HLFFKYYGTR 
EAVIAQISSH VKAIDTIYQT TDFSGIRNIS FMVKRIRINT TSDEKDPTNP FRFPNIGVEK 
FLELNSEQNH DDYCLAYVFT DRDFDDGVLG LAWVGAPSGS SGGICEKSKL YSDGKKKSLN 
TGIITVQNYG SHVPPKVSHI TFAHEVGHNF GSPHDSGTEC TPGESKNLGQ KENGNYIMYA 
RATSGDKLNN NKFSLCSIRN ISQVLEKKRN NCFVESGQPI CGNGMVEQGE ECDCGYSDQC 
KDECCFDANQ PEGKKCKLKP GKQCSPSQGP CCTAQCAFKS KSEKCRDDSD CAKEGICNGF 
TALCPASDPK PNFTDCNRHT QVCINGQCAG SICEKYDLEE CTCASSDGKD DKELCHVCCM 
KKMAPSTCAS TGSLQWNKQF NGRTITLQPG SPCNDFRGYC DVFMRCRLVD ADGPLARLKK 
AIFSPQLYEN IAEWIVAHWW AVLLMGIALI MLMAGFIKIC SVHTPSSNPK LPPPKPLPGT 
LKRRRPPQPI QQPPRQRPRE SYQMGHMRR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.