P2rx7 | ENSRNOG00000001296 | NCBI 29665

Details for: P2rx7

Gene ID: 29665

Symbol: P2rx7

Ensembl ID: ENSRNOG00000001296

Description: purinergic receptor P2X 7

Associated with

Atp binding
(GO:0005524)
Bleb assembly
(GO:0032060)
Calcium ion transport
(GO:0006816)
Cell morphogenesis
(GO:0000902)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to extracellular stimulus
(GO:0031668)
Cell volume homeostasis
(GO:0006884)
Ceramide biosynthetic process
(GO:0046513)
Channel activity
(GO:0015267)
Collagen metabolic process
(GO:0032963)
Copper ion binding
(GO:0005507)
Defense response to gram-positive bacterium
(GO:0050830)
Extracellularly atp-gated monoatomic cation channel activity
(GO:0004931)
Gamma-aminobutyric acid secretion
(GO:0014051)
Gene expression
(GO:0010467)
Glutamate secretion
(GO:0014047)
Homeostasis of number of cells within a tissue
(GO:0048873)
Identical protein binding
(GO:0042802)
Inflammatory response
(GO:0006954)
Lipopolysaccharide binding
(GO:0001530)
Magnesium ion binding
(GO:0000287)
Mapk cascade
(GO:0000165)
Membrane protein ectodomain proteolysis
(GO:0006509)
Mitochondrion organization
(GO:0007005)
Monoatomic cation transport
(GO:0006812)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Nad transport
(GO:0043132)
Negative regulation of bone resorption
(GO:0045779)
Negative regulation of cell volume
(GO:0045794)
Negative regulation of mapk cascade
(GO:0043409)
Neuronal action potential
(GO:0019228)
Phagolysosome assembly
(GO:0001845)
Phospholipid transfer to membrane
(GO:0006649)
Phospholipid translocation
(GO:0045332)
Plasma membrane organization
(GO:0007009)
Plasma membrane phospholipid scrambling
(GO:0017121)
Pore complex assembly
(GO:0046931)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of bone mineralization
(GO:0030501)
Positive regulation of calcium ion transport into cytosol
(GO:0010524)
Positive regulation of cytoskeleton organization
(GO:0051495)
Positive regulation of gamma-aminobutyric acid secretion
(GO:0014054)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glutamate secretion
(GO:0014049)
Positive regulation of glycolytic process
(GO:0045821)
Positive regulation of interleukin-1 alpha production
(GO:0032730)
Positive regulation of interleukin-1 beta production
(GO:0032731)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of monoatomic ion transmembrane transport
(GO:0034767)
Positive regulation of ossification
(GO:0045778)
Positive regulation of prostaglandin secretion
(GO:0032308)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of t cell mediated cytotoxicity
(GO:0001916)
Programmed cell death
(GO:0012501)
Prostaglandin secretion
(GO:0032310)
Protein binding
(GO:0005515)
Protein catabolic process
(GO:0030163)
Protein processing
(GO:0016485)
Protein secretion
(GO:0009306)
Protein serine/threonine kinase activator activity
(GO:0043539)
Purinergic nucleotide receptor activity
(GO:0001614)
Purinergic nucleotide receptor signaling pathway
(GO:0035590)
Regulation of sodium ion transport
(GO:0002028)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to atp
(GO:0033198)
Response to bacterium
(GO:0009617)
Response to calcium ion
(GO:0051592)
Response to electrical stimulus
(GO:0051602)
Response to fluid shear stress
(GO:0034405)
Response to lipopolysaccharide
(GO:0032496)
Response to mechanical stimulus
(GO:0009612)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to xenobiotic stimulus
(GO:0009410)
Response to zinc ion
(GO:0010043)
Scaffold protein binding
(GO:0097110)
Sensory perception of pain
(GO:0019233)
Signaling receptor activity
(GO:0038023)
Signaling receptor binding
(GO:0005102)
Skeletal system morphogenesis
(GO:0048705)
Synaptic vesicle exocytosis
(GO:0016079)
T cell homeostasis
(GO:0043029)
T cell mediated cytotoxicity
(GO:0001913)
T cell proliferation
(GO:0042098)
Vesicle budding from membrane
(GO:0006900)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

P2X purinoceptor 7
C8YIX5_RAT

Genular Protein ID: 2230660187

Symbol: P2RX7_RAT

Name: P2X purinoceptor 7

UniProtKB Accession Codes:

Q64663

Database IDs:

Citations:

PubMed ID: 8614837

Title: The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7).

PubMed ID: 8614837

DOI: 10.1126/science.272.5262.735

PubMed ID: 24090084

Title: Site-specific glycan-peptide analysis for determination of N-glycoproteome heterogeneity.

PubMed ID: 24090084

DOI: 10.1021/pr400783j

Sequence Information:

Length: 595
Mass: 68392
Checksum: 4A6DD6058E5988D3
Sequence:

MPACCSWNDV FQYETNKVTR IQSVNYGTIK WILHMTVFSY VSFALMSDKL YQRKEPLISS 
VHTKVKGVAE VTENVTEGGV TKLVHGIFDT ADYTLPLQGN SFFVMTNYLK SEGQEQKLCP 
EYPSRGKQCH SDQGCIKGWM DPQSKGIQTG RCIPYDQKRK TCEIFAWCPA EEGKEAPRPA 
LLRSAENFTV LIKNNIDFPG HNYTTRNILP GMNISCTFHK TWNPQCPIFR LGDIFQEIGE 
NFTEVAVQGG IMGIEIYWDC NLDSWSHRCQ PKYSFRRLDD KYTNESLFPG YNFRYAKYYK 
ENGMEKRTLI KAFGVRFDIL VFGTGGKFDI IQLVVYIGST LSYFGLATVC IDLIINTYAS 
TCCRSRVYPS CKCCEPCAVN EYYYRKKCEP IVEPKPTLKY VSFVDEPHIW MVDQQLLGKS 
LQDVKGQEVP RPQTDFLELS RLSLSLHHSP PIPGQPEEMQ LLQIEAVPRS RDSPDWCQCG 
NCLPSQLPEN RRALEELCCR RKPGQCITTS ELFSKIVLSR EALQLLLLYQ EPLLALEGEA 
INSKLRHCAY RSYATWRFVS QDMADFAILP SCCRWKIRKE FPKTQGQYSG FKYPY

Genular Protein ID: 516595549

Symbol: C8YIX5_RAT

Name: N/A

UniProtKB Accession Codes:

C8YIX5

Database IDs:

Citations:

PubMed ID: 19546214

Title: A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice.

PubMed ID: 19546214

DOI: 10.1074/jbc.M109.033134

Sequence Information:

Length: 592
Mass: 67890
Checksum: 7C4F3E01BD077725
Sequence:

MLPVRHLCSY NSAKVLHIHS TRLGALKNFF LLAICIYICF ALMSDKLYQR KEPLISSVHT 
KVKGVAEVTE NVTEGGVTKL VHGIFDTADY TLPLQGNSFF VMTNYLKSEG QEQKLCPEYP 
SRGKQCHSDQ GCIKGWMDPQ SKGIQTGRCI PYDQKRKTCE IFAWCPAEEG KEAPRPALLR 
SAENFTVLIK NNIDFPGHNY TTRNILPGMN ISCTFHKTWN PQCPIFRLGD IFQEIGENFT 
EVAVQGGIMG IEIYWDCNLD SWSHRCQPKY SFRRLDDKYT NESLFPGYNF RYAKYYKENG 
MEKRTLIKAF GVRFDILVFG TGGKFDIIQL VVYIGSTLSY FGLATVCIDL IINTYASTCC 
RSRVYPSCKC CEPCAVNEYY YRKKCEPIVE PKPTLKYVSF VDEPHIWMVD QQLLGKSLQD 
VKGQEVPRPQ TDFLELSRLS LSLHHSPPIP GQPEEMQLLQ IEAVPRSRDS PDWCQCGNCL 
PSQLPENRRA LEELCCRRKP GQCITTSELF SKIVLSREAL QLLLLYQEPL LALEGEAINS 
KLRHCAYRSY ATWRFVSQDM ADFAILPSCC RWKIRKEFPK TQGQYSGFKY PY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.