Atp2a2 | ENSRNOG00000001285 | NCBI 29693

Details for: Atp2a2

Gene ID: 29693

Symbol: Atp2a2

Ensembl ID: ENSRNOG00000001285

Description: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

Associated with

Cardiac conduction
(R-RNO-5576891)
Hemostasis
(R-RNO-109582)
Ion channel transport
(R-RNO-983712)
Ion homeostasis
(R-RNO-5578775)
Ion transport by p-type atpases
(R-RNO-936837)
Muscle contraction
(R-RNO-397014)
Platelet calcium homeostasis
(R-RNO-418360)
Platelet homeostasis
(R-RNO-418346)
Reduction of cytosolic ca++ levels
(R-RNO-418359)
Transport of small molecules
(R-RNO-382551)
Apical ectoplasmic specialization
(GO:0061831)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Autophagosome assembly
(GO:0000045)
Autophagosome membrane docking
(GO:0016240)
Calcium ion-transporting atpase complex
(GO:0090534)
Calcium ion binding
(GO:0005509)
Calcium ion import into sarcoplasmic reticulum
(GO:1990036)
Calcium ion transmembrane transport
(GO:0070588)
Calcium ion transport
(GO:0006816)
Calcium ion transport from cytosol to endoplasmic reticulum
(GO:1903515)
Cardiac muscle hypertrophy in response to stress
(GO:0014898)
Cellular response to heat
(GO:0034605)
Cellular response to oxidative stress
(GO:0034599)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum calcium ion homeostasis
(GO:0032469)
Endoplasmic reticulum membrane
(GO:0005789)
Enzyme binding
(GO:0019899)
Er-nucleus signaling pathway
(GO:0006984)
Extrinsic component of cytoplasmic side of plasma membrane
(GO:0031234)
Intercalated disc
(GO:0014704)
Intracellular calcium ion homeostasis
(GO:0006874)
Lncrna binding
(GO:0106222)
Longitudinal sarcoplasmic reticulum
(GO:0014801)
Lutropin-choriogonadotropic hormone receptor binding
(GO:0031775)
Membrane
(GO:0016020)
Mitochondrion-endoplasmic reticulum membrane tethering
(GO:1990456)
Negative regulation of heart contraction
(GO:0045822)
Neuron cellular homeostasis
(GO:0070050)
Organelle localization by membrane tethering
(GO:0140056)
Organelle organization
(GO:0006996)
P-type calcium transporter activity
(GO:0005388)
P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential
(GO:0086039)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane bounded cell projection
(GO:0120025)
Positive regulation of cardiac muscle cell apoptotic process
(GO:0010666)
Positive regulation of endoplasmic reticulum calcium ion concentration
(GO:0032470)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Regulation of calcium ion-dependent exocytosis of neurotransmitter
(GO:1903233)
Regulation of cardiac muscle cell action potential involved in regulation of contraction
(GO:0098909)
Regulation of cardiac muscle cell membrane potential
(GO:0086036)
Regulation of cardiac muscle contraction by calcium ion signaling
(GO:0010882)
Regulation of the force of heart contraction
(GO:0002026)
Relaxation of cardiac muscle
(GO:0055119)
Relaxation of skeletal muscle
(GO:0090076)
Response to endoplasmic reticulum stress
(GO:0034976)
Response to lipopolysaccharide
(GO:0032496)
Response to peptide hormone
(GO:0043434)
Ribbon synapse
(GO:0097470)
S100 protein binding
(GO:0044548)
Sarcoplasmic reticulum
(GO:0016529)
Sarcoplasmic reticulum calcium ion transport
(GO:0070296)
Sarcoplasmic reticulum membrane
(GO:0033017)
T-tubule organization
(GO:0033292)
Transition between fast and slow fiber
(GO:0014883)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Genular Protein ID: 977951165

Symbol: AT2A2_RAT

Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

UniProtKB Accession Codes:

P11507 P11508

Database IDs:

Citations:

PubMed ID: 2844797

Title: A novel Ca2+ pump expressed in brain, kidney, and stomach is encoded by an alternative transcript of the slow-twitch muscle sarcoplasmic reticulum Ca-ATPase gene. Identification of cDNAs encoding Ca2+ and other cation-transporting ATPases using an oligonucleotide probe derived from the ATP-binding site.

PubMed ID: 2844797

DOI: 10.1016/s0021-9258(18)68142-6

PubMed ID: 2542094

Title: Characterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA.

PubMed ID: 2542094

DOI: 10.1016/0014-5793(89)80010-9

PubMed ID: 10359649

Title: Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.

PubMed ID: 10359649

DOI: 10.1042/bj3400657

PubMed ID: 16399855

Title: Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.

PubMed ID: 16399855

DOI: 10.1152/ajpheart.01293.2005

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 1043
Mass: 114768
Checksum: 4B0B476BFD97F390
Sequence:

MENAHTKTVE EVLGHFGVNE STGLSLEQVK KLKERWGSNE LPAEEGKTLL ELVIEQFEDL 
LVRILLLAAC ISFVLAWFEE GEETITAFVE PFVILLILVA NAIVGVWQER NAENAIEALK 
EYEPEMGKVY RQDRKSVQRI KAKDIVPGDI VEIAVGDKVP ADIRLTSIKS TTLRVDQSIL 
TGESVSVIKH TDPVPDPRAV NQDKKNMLFS GTNIAAGKAM GVVVATGVNT EIGKIRDEMV 
ATEQERTPLQ QKLDEFGEQL SKVISLICIA VWIINIGHFN DPVHGGSWIR GAIYYFKIAV 
ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ 
MSVCRMFILD KVEGDTCSLN EFTITGSTYA PIGEVQKDDK PVKCHQYDGL VELATICALC 
NDSALDYNEA KGVYEKVGEA TETALTCLVE KMNVFDTELK GLSKIERANA CNSVIKQLMK 
KEFTLEFSRD RKSMSVYCTP NKPSRTSMSK MFVKGAPEGV IDRCTHIRVG STKVPMTPGV 
KQKIMSVIRE WGSGSDTLRC LALATHDNPL RREEMHLEDS ANFIKYETNL TFVGCVGMLD 
PPRIEVASSV KLCRQAGIRV IMITGDNKGT AVAICRRIGI FGQDEDVTSK AFTGREFDEL 
SPSAQRDACL NARCFARVEP SHKSKIVEFL QSFDEITAMT GDGVNDAPAL KKSEIGIAMG 
SGTAVAKTAS EMVLADDNFS TIVAAVEEGR AIYNNMKQFI RYLISSNVGE VVCIFLTAAL 
GFPEALIPVQ LLWVNLVTDG LPATALGFNP PDLDIMNKPP RNPKEPLISG WLFFRYLAIG 
CYVGAATVGA AAWWFIAADG GPRVSFYQLS HFLQCKEDNP DFEGVDCAIF ESPYPMTMAL 
SVLVTIEMCN ALNSLSENQS LLRMPPWENI WLVGSICLSM SLHFLILYVE PLPLIFQITP 
LNLTQWLMVL KISLPVILMD ETLKFVARNY LEPGKECAQP ATKPSCSLSA CTDGISWPFV 
LLIMPLVVWV YSTDTNFSDM FWS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp2a2

Associated with

Other Information

Characterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA. PubMed ID: 2542094

Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle. PubMed ID: 10359649

Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging. PubMed ID: 16399855

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Database document:

PubMed ID: 2542094

PubMed ID: 10359649

PubMed ID: 16399855

PubMed ID: 22673903