Details for: Gabra1

Gene ID: 29705

Symbol: Gabra1

Ensembl ID: ENSRNOG00000003512

Description: gamma-aminobutyric acid type A receptor subunit alpha 1

Associated with

Other Information

Genular Protein ID: 3275248383

Symbol: GBRA1_RAT

Name: Gamma-aminobutyric acid receptor subunit alpha-1

UniProtKB Accession Codes:

P62813 P18504 Q53YK4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Bgee 1 BindingDB 1 BioGRID 1 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ComplexPortal 2 DrugCentral 1 EMBL 3 EMDB 2 Ensembl 4 GO 27 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MINT 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PIR 1 PRINTS 4 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 4 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 3 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2540033

Title: Cloning and expression of a novel rat GABAA receptor.

PubMed ID: 2540033

DOI: 10.1016/0014-5793(89)80271-6

PubMed ID: 2561977

Title: A novel alpha subunit in rat brain GABAA receptors.

PubMed ID: 2561977

DOI: 10.1016/0896-6273(89)90243-2

PubMed ID: 1977069

Title: GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands.

PubMed ID: 1977069

DOI: 10.1016/0169-328x(90)90017-8

PubMed ID: 1966765

Title: The GABAA receptor family: molecular and functional diversity.

PubMed ID: 1966765

DOI: 10.1101/sqb.1990.055.01.006

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1376242

Title: Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

PubMed ID: 1376242

DOI: 10.1002/j.1460-2075.1992.tb05258.x

PubMed ID: 11528422

Title: GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.

PubMed ID: 11528422

DOI: 10.1038/nn0901-908

PubMed ID: 18281286

Title: Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.

PubMed ID: 18281286

DOI: 10.1074/jbc.m709993200

PubMed ID: 25172774

Title: The kinesin KIF21B participates in the cell surface delivery of gamma2 subunit-containing GABAA receptors.

PubMed ID: 25172774

DOI: 10.1016/j.ejcb.2014.07.007

PubMed ID: 28279354

Title: GARLH family proteins stabilize GABAA receptors at synapses.

PubMed ID: 28279354

DOI: 10.1016/j.neuron.2017.02.023

Sequence Information:

  • Length: 455
  • Mass: 51754
  • Checksum: A270B43423B4086E
  • Sequence:
    • MKKSRGLSDY LWAWTLILST LSGRSYGQPS QDELKDNTTV FTRILDRLLD GYDNRLRPGL 
GERVTEVKTD IFVTSFGPVS DHDMEYTIDV FFRQSWKDER LKFKGPMTVL RLNNLMASKI 
WTPDTFFHNG KKSVAHNMTM PNKLLRITED GTLLYTMRLT VRAECPMHLE DFPMDAHACP 
LKFGSYAYTR AEVVYEWTRE PARSVVVAED GSRLNQYDLL GQTVDSGIVQ SSTGEYVVMT 
THFHLKRKIG YFVIQTYLPC IMTVILSQVS FWLNRESVPA RTVFGVTTVL TMTTLSISAR 
NSLPKVAYAT AMDWFIAVCY AFVFSALIEF ATVNYFTKRG YAWDGKSVVP EKPKKVKDPL 
IKKNNTYAPT ATSYTPNLAR GDPGLATIAK SATIEPKEVK PETKPPEPKK TFNSVSKIDR 
LSRIAFPLLF GIFNLVYWAT YLNREPQLKA PTPHQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.