Gabrg2 | ENSRNOG00000003241 | NCBI 29709

Details for: Gabrg2

Gene ID: 29709

Symbol: Gabrg2

Ensembl ID: ENSRNOG00000003241

Description: gamma-aminobutyric acid type A receptor subunit gamma 2

Associated with

Gaba receptor activation
(R-RNO-977443)
Neuronal system
(R-RNO-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-RNO-112314)
Transmission across chemical synapses
(R-RNO-112315)
Adult behavior
(GO:0030534)
Axon
(GO:0030424)
Benzodiazepine receptor activity
(GO:0008503)
Cell surface
(GO:0009986)
Cellular response to histamine
(GO:0071420)
Cellular response to zinc ion
(GO:0071294)
Chemical synaptic transmission
(GO:0007268)
Chloride channel activity
(GO:0005254)
Chloride channel complex
(GO:0034707)
Chloride transmembrane transport
(GO:1902476)
Chloride transport
(GO:0006821)
Cytoplasmic vesicle membrane
(GO:0030659)
Dendrite membrane
(GO:0032590)
Dendritic spine
(GO:0043197)
Gaba-a receptor activity
(GO:0004890)
Gaba-a receptor complex
(GO:1902711)
Gaba-ergic synapse
(GO:0098982)
Gaba-gated chloride ion channel activity
(GO:0022851)
Gaba receptor activity
(GO:0016917)
Gaba receptor complex
(GO:1902710)
Gamma-aminobutyric acid signaling pathway
(GO:0007214)
Glutamatergic synapse
(GO:0098978)
Inhibitory extracellular ligand-gated monoatomic ion channel activity
(GO:0005237)
Inhibitory synapse
(GO:0060077)
Inhibitory synapse assembly
(GO:1904862)
Neuron projection
(GO:0043005)
Plasma membrane
(GO:0005886)
Post-embryonic development
(GO:0009791)
Postsynapse
(GO:0098794)
Postsynaptic membrane
(GO:0045211)
Postsynaptic specialization membrane
(GO:0099634)
Protein binding
(GO:0005515)
Regulation of postsynaptic membrane potential
(GO:0060078)
Response to anesthetic
(GO:0072347)
Response to ethanol
(GO:0045471)
Synapse
(GO:0045202)
Synaptic transmission, gabaergic
(GO:0051932)
Transmembrane transporter complex
(GO:1902495)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)

Other Information

Proteins

GBRG2_RAT

Genular Protein ID: 304236844

Symbol: GBRG2_RAT

Name: N/A

UniProtKB Accession Codes:

P18508

Database IDs:

Citations:

PubMed ID: 2561970

Title: Two novel GABAA receptor subunits exist in distinct neuronal subpopulations.

PubMed ID: 2561970

DOI: 10.1016/0896-6273(89)90257-2

PubMed ID: 2165521

Title: Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor.

PubMed ID: 2165521

DOI: 10.1523/jneurosci.10-07-02330.1990

PubMed ID: 9464994

Title: Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells.

PubMed ID: 9464994

DOI: 10.1523/jneurosci.18-05-01693.1998

PubMed ID: 17003036

Title: A novel function of ionotropic gamma-aminobutyric acid receptors involving alveolar fluid homeostasis.

PubMed ID: 17003036

DOI: 10.1074/jbc.m606895200

PubMed ID: 25172774

Title: The kinesin KIF21B participates in the cell surface delivery of gamma2 subunit-containing GABAA receptors.

PubMed ID: 25172774

DOI: 10.1016/j.ejcb.2014.07.007

PubMed ID: 28279354

Title: GARLH family proteins stabilize GABAA receptors at synapses.

PubMed ID: 28279354

DOI: 10.1016/j.neuron.2017.02.023

PubMed ID: 30044221

Title: Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA.

PubMed ID: 30044221

DOI: 10.7554/elife.39383

Sequence Information:

Length: 466
Mass: 54077
Checksum: 3C60B66E0D23072F
Sequence:

MSSPNTWSTG STVYSPVFSQ KMTLWILLLL SLYPGFTSQK SDDDYEDYAS NKTWVLTPKV 
PEGDVTVILN NLLEGYDNKL RPDIGVKPTL IHTDMYVNSI GPVNAINMEY TIDIFFAQTW 
YDRRLKFNST IKVLRLNSNM VGKIWIPDTF FRNSKKADAH WITTPNRMLR IWNDGRVLYT 
LRLTIDAECQ LQLHNFPMDE HSCPLEFSSY GYPREEIVYQ WKRSSVEVGD TRSWRLYQFS 
FVGLRNTTEV VKTTSGDYVV MSVYFDLSRR MGYFTIQTYI PCTLIVVLSW VSFWINKDAV 
PARTSLGITT VLTMTTLSTI ARKSLPKVSY VTAMDLFVSV CFIFVFSALV EYGTLHYFVS 
NRKPSKDKDK KKKNPAPTID IRPRSATIQM NNATHLQERD EEYGYECLDG KDCASFFCCF 
EDCRTGAWRH GRIHIRIAKM DSYARIFFPT AFCLFNLVYW VSYLYL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gabrg2

Associated with

Other Information

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. PubMed ID: 2561970

Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor. PubMed ID: 2165521

Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. PubMed ID: 9464994

A novel function of ionotropic gamma-aminobutyric acid receptors involving alveolar fluid homeostasis. PubMed ID: 17003036

The kinesin KIF21B participates in the cell surface delivery of gamma2 subunit-containing GABAA receptors. PubMed ID: 25172774

GARLH family proteins stabilize GABAA receptors at synapses. PubMed ID: 28279354

Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA. PubMed ID: 30044221