Details for: Kcnj5

Gene ID: 29713

Symbol: Kcnj5

Ensembl ID: ENSRNOG00000033796

Description: potassium inwardly-rectifying channel, subfamily J, member 5

Associated with

  • Activation of gabab receptors
    (R-RNO-991365)
  • Activation of g protein gated potassium channels
    (R-RNO-1296041)
  • Gaba b receptor activation
    (R-RNO-977444)
  • Gaba receptor activation
    (R-RNO-977443)
  • G protein gated potassium channels
    (R-RNO-1296059)
  • Inhibition of voltage gated ca2+ channels via gbeta/gamma subunits
    (R-RNO-997272)
  • Inwardly rectifying k+ channels
    (R-RNO-1296065)
  • Neuronal system
    (R-RNO-112316)
  • Neurotransmitter receptors and postsynaptic signal transmission
    (R-RNO-112314)
  • Potassium channels
    (R-RNO-1296071)
  • Transmission across chemical synapses
    (R-RNO-112315)
  • External side of plasma membrane
    (GO:0009897)
  • G-protein activated inward rectifier potassium channel activity
    (GO:0015467)
  • Inward rectifier potassium channel activity
    (GO:0005242)
  • Membrane repolarization during atrial cardiac muscle cell action potential
    (GO:0098914)
  • Plasma membrane
    (GO:0005886)
  • Potassium ion import across plasma membrane
    (GO:1990573)
  • Regulation of heart rate by cardiac conduction
    (GO:0086091)
  • Regulation of monoatomic ion transmembrane transport
    (GO:0034765)
  • T-tubule
    (GO:0030315)
  • Voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
    (GO:0086089)
  • Voltage-gated potassium channel complex
    (GO:0008076)

Other Information

Genular Protein ID: 1969836280

Symbol: KCNJ5_RAT

Name: G protein-activated inward rectifier potassium channel 4

UniProtKB Accession Codes:

P48548

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CTD 1 ChEMBL 1 ComplexPortal 1 DNASU 1 EMBL 4 Ensembl 3 GO 11 Gene3D 2 GeneTree 1 Genevisible 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 2 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8047164

Title: Cloning and functional expression of a rat heart KATP channel.

PubMed ID: 8047164

DOI: 10.1038/370456a0

PubMed ID: 8524415

Title:

PubMed ID: 8524415

DOI: 10.1038/378792a0

PubMed ID: 7877685

Title: The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins.

PubMed ID: 7877685

DOI: 10.1038/374135a0

PubMed ID: 7592809

Title: Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels.

PubMed ID: 7592809

DOI: 10.1074/jbc.270.44.26086

PubMed ID: 8834003

Title: Functional characterization and localization of a cardiac-type inwardly rectifying K+ channel.

PubMed ID: 8834003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 419
  • Mass: 47783
  • Checksum: DFF537CD79A7370D
  • Sequence:
    • MAGDSRNAMN QDMEIGVTSQ DHKKIPKQAR DYIPIATDRT RLLPEGKKPR QRYMEKTGKC 
NVHHGNVQET YRYLSDLFTT LVDLKWRFNL LVFTMVYTIT WLFFGFIWWL IAYVRGDLDH 
VGDQEWIPCV ENLSGFVSAF LFSIETETTI GYGFRVITEK CPEGIILLLV QAILGSIVNA 
FMVGCMFVKI SQPKKRAETL MFSNNAVISM RDEKLCLMFR VGDLRNSHIV EASIRAKLIK 
SRQTKEGEFI PLNQTDINVG FDTGDDRLFL VSPLIISHEI NEKSPFWEMS RAQLEQEEFE 
VVVILEGMVE ATGMTCQARS SYMDTEVLWG HRFTPVLTLE KGFYEVDYNT FHDTYETNTP 
SCCAKELAEM KRNGQLLQSL PSPPLLGGCA EAEKEAEAEH DEEEEPNGLS VSRATRGSM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.