Details for: Ptprn2

Gene ID: 29714

Symbol: Ptprn2

Ensembl ID: ENSRNOG00000005003

Description: protein tyrosine phosphatase, receptor type N2

Associated with

Other Information

Genular Protein ID: 2109705253

Symbol: PTPR2_RAT

Name: Receptor-type tyrosine-protein phosphatase N2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8663434

Title: Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes.

PubMed ID: 8663434

DOI: 10.1074/jbc.271.30.18161

PubMed ID: 11353772

Title: Secretagogue-dependent phosphorylation of the insulin granule membrane protein phogrin is mediated by cAMP-dependent protein kinase.

PubMed ID: 11353772

DOI: 10.1074/jbc.m102580200

PubMed ID: 14597614

Title: Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A.

PubMed ID: 14597614

DOI: 10.1074/jbc.m310104200

PubMed ID: 15882444

Title: An extended tyrosine-targeting motif for endocytosis and recycling of the dense-core vesicle membrane protein phogrin.

PubMed ID: 15882444

DOI: 10.1111/j.1600-0854.2005.00292.x

PubMed ID: 20097759

Title: The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.

PubMed ID: 20097759

DOI: 10.1074/jbc.m109.066563

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 25744490

Title: HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic beta cells.

PubMed ID: 25744490

DOI: 10.1007/s00418-015-1311-9

Sequence Information:

  • Length: 1004
  • Mass: 111863
  • Checksum: A73929E11B486FB2
  • Sequence:
  • MGLPLPLLLL LLLPPPLPRA LPAPASARGR QLPGRLGCLF EDGLCGSLET CVNDGVFGRC 
    QKVPALDTYR YEVSPGALLH LRIILQKLSR TGFTWQDDYT QRVIAQELSN LPKAYLWHEE 
    ASSPARSLQQ NADNEKWFSL ESEVALAKTL RRYLPYLELL SQAPTANAHP RIDHETRPVK 
    GEDSSPENIL TYVAHTSALT YPPATRVKYP DNLLRPLSRL QPDELSPKVD SDIDKQKLIA 
    ALGAYTAQRP PGENDPEPRY LVHSPMRAPR PFAAPALSQR WPLPPGDSKD SLSMGDDTLL 
    RSLLKDLQQQ AEVDRLGSLK LEEQADSIAG AIQSDPVEGS QESHGRGAEG QLREQADAPE 
    EMLQDHRLPE VDDPAAYKEV SRLSFKLGDL LKDHGSPLLP EAPLLEKSSR AEMKKSEQPE 
    EVLSSEEETA GVEHVKSRTY SKDLLERKPN SEPQPWRLED QFQNRAPEVW EDEQNLKLAA 
    QGPPSGGLQL EVQPSEEEQQ GYILTGNNPL SPEKGKQLMD EVAHLLRVPS SFFADVKVLG 
    PAVIFKVSAN IQNMTTADVT KAAVDNKDEL EKATGLTILQ SGIRPKGKLK LLPHPEEQED 
    STKFIVLTFL SIACILAVLL ASSLAYCLRH NSHYKLKEKL SGLGADPSAD ATEAYQELCR 
    QRMAVRPQDH SEGPHTSRIN SVSSQLSDGP MPSPSARSST SSWSEEPAQS NMDISTGHMI 
    LAYMEDHLKN KNRLEKEWEA LCAYQAEPDS SLVAQREENA PKNRSLAVLT YDHSRILLKS 
    ENSHSNSDYI NASPIMDHDP RNPAYIATQG PLPATVADFW QMVWESGCAV IVMLTPLSEN 
    GVRQCHHYWP DEGSNVYHVY EVNLVSEHIW CQDFLVRSFY LKNLQTNETR TVTQFHFLSW 
    YDQGVPSSTR SLLDFRRKVN KCYRGRSCPI IVHCSDGAGR SGTYVLIDMV LNKMAKGAKE 
    IDIAATLEHL RDQRPGMVQT KEQFEFALTA VAEEVNAILK ALPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.