Gclm | ENSRNOG00000013409 | NCBI 29739

Details for: Gclm

Gene ID: 29739

Symbol: Gclm

Ensembl ID: ENSRNOG00000013409

Description: glutamate cysteine ligase, modifier subunit

Associated with

Biological oxidations
(R-RNO-211859)
Glutathione conjugation
(R-RNO-156590)
Glutathione synthesis and recycling
(R-RNO-174403)
Metabolism
(R-RNO-1430728)
Phase ii - conjugation of compounds
(R-RNO-156580)
Apoptotic mitochondrial changes
(GO:0008637)
Blood vessel diameter maintenance
(GO:0097746)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to hepatocyte growth factor stimulus
(GO:0035729)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Cellular response to thyroxine stimulus
(GO:0097069)
Cysteine metabolic process
(GO:0006534)
Enzyme regulator activity
(GO:0030234)
Glutamate-cysteine ligase activity
(GO:0004357)
Glutamate-cysteine ligase catalytic subunit binding
(GO:0035226)
Glutamate-cysteine ligase complex
(GO:0017109)
Glutamate metabolic process
(GO:0006536)
Glutathione biosynthetic process
(GO:0006750)
Glutathione metabolic process
(GO:0006749)
Hepatic stellate cell activation
(GO:0035733)
Negative regulation of extrinsic apoptotic signaling pathway
(GO:2001237)
Negative regulation of neuron apoptotic process
(GO:0043524)
Positive regulation of glutamate-cysteine ligase activity
(GO:0035229)
Protein-containing complex binding
(GO:0044877)
Regulation of mitochondrial depolarization
(GO:0051900)
Response to activity
(GO:0014823)
Response to human chorionic gonadotropin
(GO:0044752)
Response to nitrosative stress
(GO:0051409)
Response to nutrient
(GO:0007584)
Response to oxidative stress
(GO:0006979)
Response to xenobiotic stimulus
(GO:0009410)

Other Information

Proteins

Glutamate--cysteine ligase regulatory subunit

Genular Protein ID: 35280109

Symbol: GSH0_RAT

Name: Glutamate--cysteine ligase regulatory subunit

UniProtKB Accession Codes:

P48508

Database IDs:

Citations:

PubMed ID: 8104188

Title: Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase.

PubMed ID: 8104188

DOI: 10.1016/s0021-9258(20)80764-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 274
Mass: 30548
Checksum: C99E35591C96C9CC
Sequence:

MGTDSRAAGA LLARASTLHL QTGNLLNWGR LRKKCPSTHS EELRDCIQKT LNEWSSQISP 
DLVREFPDVL ECTMSHAVEK INPDEREEMK VSAKLFIVGS NSSSSTRNAV DMACSVLGVA 
QLDSVIMASP PIEDGVNLSL EHLQPYWEEL ENLVQSKKIV AIGTSDLDKT QLEQLYQWAQ 
VKPNSNQVNL ASCCVMPPDL TAFAKQFDIQ LLTHNDPKEL LSEASFQEAL QESIPDIEAQ 
EWVPLWLLRY SVIVKSRGII KSKGYILQAK RKGS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.