Details for: Bcar3

Gene ID: 29815

Symbol: Bcar3

Ensembl ID: ENSMUSG00000028121

Description: breast cancer anti-estrogen resistance 3

Associated with

Other Information

Genular Protein ID: 1967809870

Symbol: BCAR3_MOUSE

Name: Breast cancer anti-estrogen resistance protein 3 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10438950

Title: AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines.

PubMed ID: 10438950

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10896938

Title: p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

PubMed ID: 10896938

DOI: 10.1074/jbc.m003074200

PubMed ID: 12517963

Title: The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42.

PubMed ID: 12517963

DOI: 10.4049/jimmunol.170.2.969

PubMed ID: 19103205

Title: Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance.

PubMed ID: 19103205

DOI: 10.1016/j.jmb.2008.12.010

PubMed ID: 19365570

Title: Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens.

PubMed ID: 19365570

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22801373

Title: Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.

PubMed ID: 22801373

DOI: 10.1128/mcb.00214-12

PubMed ID: 25499443

Title: Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor beta/Smad signaling and associates with favorable breast cancer disease outcomes.

PubMed ID: 25499443

DOI: 10.1186/s13058-014-0476-9

Sequence Information:

  • Length: 820
  • Mass: 92263
  • Checksum: 69DDACECDE869F01
  • Sequence:
  • MAAGKFASLP RNMPVNHQFP LASSMDLLSS KSPLAERRTD AYQDVSIHGT LPRKKKGPPS 
    IRSCDNAGHS KSPRQSSPLT QDIIQENPLQ DRKGENFIFR DPYLLDPTLE YVKFSKERHI 
    MDRTPERLKK ELEEELLLSS EDLRSHAWYH GRIPRQVSEN LVQRDGDFLV RDSLSSPGNF 
    VLTCQWKNLA QHFKINRTVL RLSEAYSRVQ YQFEMESFDS IPGLVRCYVG NRRPISQQSG 
    AIIFQPINRT VPLWCLEERY GTSPGRGREG SLAEGRPDVV KRLSLTTGSS IQAREHSLPR 
    GNLLRNKEKS GSQPACLDHV QDRKALTLKA HQSESHLPIG CKLPPQSPSM DTSPCPSSPV 
    FRTGSEPTLS PALVRRFSSD ARTGEALRGS DSQLCPKPPP KPCKVPFLKT PPSPSPWLTS 
    EANYCELNPA FAVGCDRGAK LPMQAHDSHE MLLTAKQNGP SGPRNSGINY MILDGDDQAR 
    HWDPLAVQTD EGQEDKTKFV PPLMETVSSF RPNDFESKLL PPENKPLETA MLKHAKELFT 
    NHDARVIAQH MLSVDCKVAR ILEVSEDRKR SMGVSSGLEL ITLPHGRQLR LDIIERHNTM 
    AIGIAVDILG CTGTLENRAG TLNKIIQVAV ELKDAMGDLY AFSAIMKALE MPQITRLEKT 
    WTALRHHYTQ TAILYEKQLK PFSKILHEGR ESTYVPASNV SVPLLMPLVT LMERQAVTFE 
    GTDMWENNDE SCEILLNHLA TARFMAEASE SYRMNAERIL ADFQPDEEMT EILRTEFQMR 
    LLWGSKGAEV NQNERYDKFN QILTALSRKL EPPSGKQAEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.