Hip1r | ENSMUSG00000000915 | NCBI 29816

Details for: Hip1r

Gene ID: 29816

Symbol: Hip1r

Ensembl ID: ENSMUSG00000000915

Description: huntingtin interacting protein 1 related

Associated with

Clathrin-mediated endocytosis
(R-MMU-8856828)
Golgi associated vesicle biogenesis
(R-MMU-432722)
Membrane trafficking
(R-MMU-199991)
Trans-golgi network vesicle budding
(R-MMU-199992)
Vesicle-mediated transport
(R-MMU-5653656)
Actin binding
(GO:0003779)
Actin filament binding
(GO:0051015)
Actin filament organization
(GO:0007015)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Apical plasma membrane
(GO:0016324)
Cell cortex
(GO:0005938)
Clathrin-coated pit
(GO:0005905)
Clathrin-coated vesicle
(GO:0030136)
Clathrin adaptor activity
(GO:0035615)
Clathrin binding
(GO:0030276)
Clathrin coat assembly
(GO:0048268)
Clathrin light chain binding
(GO:0032051)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Dendrite cytoplasm
(GO:0032839)
Dendritic spine
(GO:0043197)
Digestive system development
(GO:0055123)
Endocytosis
(GO:0006897)
Glutamatergic synapse
(GO:0098978)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Membrane organization
(GO:0061024)
Negative regulation of actin filament polymerization
(GO:0030837)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of arp2/3 complex-mediated actin nucleation
(GO:0034316)
Neuronal cell body
(GO:0043025)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphatidylinositol-3,4,5-trisphosphate binding
(GO:0005547)
Phosphatidylinositol-3,4-bisphosphate binding
(GO:0043325)
Phosphatidylinositol-3,5-bisphosphate binding
(GO:0080025)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Phosphatidylinositol binding
(GO:0035091)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of clathrin-dependent endocytosis
(GO:2000370)
Positive regulation of clathrin coat assembly
(GO:1905445)
Positive regulation of epidermal growth factor receptor signaling pathway
(GO:0045742)
Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901030)
Positive regulation of platelet-derived growth factor receptor-beta signaling pathway
(GO:2000588)
Positive regulation of protein binding
(GO:0032092)
Postsynapse
(GO:0098794)
Postsynapse organization
(GO:0099173)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Protein stabilization
(GO:0050821)
Receptor-mediated endocytosis
(GO:0006898)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of clathrin-dependent endocytosis
(GO:2000369)
Regulation of endocytosis
(GO:0030100)
Regulation of gastric acid secretion
(GO:0060453)
Ruffle membrane
(GO:0032587)
Sh3 domain binding
(GO:0017124)
Synaptic membrane
(GO:0097060)

Other Information

Proteins

Huntingtin-interacting protein 1-related protein

Genular Protein ID: 3594313771

Symbol: HIP1R_MOUSE

Name: Huntingtin-interacting protein 1-related protein

UniProtKB Accession Codes:

Q9JKY5 Q3UJ14

Database IDs:

Citations:

PubMed ID: 10613908

Title: An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.

PubMed ID: 10613908

DOI: 10.1083/jcb.147.7.1503

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 17452370

Title: Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.

PubMed ID: 17452370

DOI: 10.1093/hmg/ddm076

PubMed ID: 18790740

Title: Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain.

PubMed ID: 18790740

DOI: 10.1074/jbc.m802863200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1068
Mass: 119426
Checksum: 992FD4D3FA3F8A6C
Sequence:

MNSIKNVPAR VLSRRPGHSL EAEREQFDKT QAISISKAIN SQEAPVKEKH ARRIILGTHH 
EKGAFTFWSY AIGLPLSSSS ILSWKFCHVL HKVLRDGHPN VLHDYQRYRS NIREIGDLWG 
HLRDQYGHLV NIYTKLLLTK ISFHLKHPQF PAGLEVTDEV LEKAAGTDVN NIFQLTVEMF 
DYMDCELKLS ESVFRQLNTA IAVSQMSSGQ CRLAPLIQVI QDCSHLYHYT VKLMFKLHSC 
LPADTLQGHR DRFHEQFHSL KNFFRRASDM LYFKRLIQIP RLPEGPPNFL RASALAEHIK 
PVVVIPEEAP EEEEPENLIE ISSAPPAGEP VVVADLFDQT FGPPNGSMKD DRDLQIENLK 
REVETLRAEL EKIKMEAQRY ISQLKGQVNG LEAELEEQRK QKQKALVDNE QLRHELAQLK 
ALQLEGARNQ GLREEAERKA SATEARYSKL KEKHSELINT HAELLRKNAD TAKQLTVTQQ 
SQEEVARVKE QLAFQMEQAK RESEMKMEEQ SDQLEKLKRE LAARAGELAR AQEALSRTEQ 
SGSELSSRLD TLNAEKEALS GVVRQREAEL LAAQSLVREK EEALSQEQQR SSQEKGELRG 
QLAEKESQEQ GLRQKLLDEQ LAVLRSAAAE AEAILQDAVS KLDDPLHLRC TSSPDYLVSR 
AQAALDSVSG LEQGHTQYLA SSEDASALVA ALTRFSHLAA DTIVNGAATS HLAPTDPADR 
LMDTCRECGA RALELVGQLQ DQTVLPRAQP SLMRAPLQGI LQLGQDLKPK SLDVRQEELG 
AMVDKEMAAT SAAIEDAVRR IEDMMSQARH ESSGVKLEVN ERILNSCTDL MKAIRLLVMT 
STSLQKEIVE SGRGAATQQE FYAKNSRWTE GLISASKAVG WGATQLVESA DKVVLHMGKY 
EELIVCSHEI AASTAQLVAA SKVKANKNSP HLSRLQECSR TVNERAANVV ASTKSGQEQI 
EDRDTMDFSG LSLIKLKKQE METQVRVLEL EKTLEAERVR LGELRKQHYV LAGGMGTPSE 
EEPSRPSPAP RSGATKKPPL AQKPSIAPRT DNQLDKKDGV YPAQLVNY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hip1r

Associated with

Other Information

An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles. PubMed ID: 10613908

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. PubMed ID: 17452370