Details for: ACAA1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 240.3481
Cell Significance Index: -37.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 140.7094
Cell Significance Index: -35.6900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 87.0385
Cell Significance Index: -35.3600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 85.4121
Cell Significance Index: -40.3300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 77.7238
Cell Significance Index: -39.9800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 60.2290
Cell Significance Index: -40.4200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 37.2352
Cell Significance Index: -35.5500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 32.0429
Cell Significance Index: -39.5100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.7293
Cell Significance Index: -34.1000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.2634
Cell Significance Index: -40.5000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.5171
Cell Significance Index: -26.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.2203
Cell Significance Index: -11.4300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 4.1298
Cell Significance Index: 38.0300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.7044
Cell Significance Index: 140.4900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.4152
Cell Significance Index: 435.3800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.1230
Cell Significance Index: 261.0500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.9839
Cell Significance Index: 119.1000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.7940
Cell Significance Index: 195.1300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.6148
Cell Significance Index: 75.2900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.2726
Cell Significance Index: 82.1000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.2680
Cell Significance Index: 251.6300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.1892
Cell Significance Index: 16.2300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.9961
Cell Significance Index: 45.1500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.9557
Cell Significance Index: 67.5900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.9173
Cell Significance Index: 125.9800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.8351
Cell Significance Index: 62.2400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.7964
Cell Significance Index: 23.3900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.7886
Cell Significance Index: 430.6500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6366
Cell Significance Index: 44.0300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5652
Cell Significance Index: 113.3700 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.5366
Cell Significance Index: 8.0400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5007
Cell Significance Index: 221.3600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.4552
Cell Significance Index: 58.3600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4480
Cell Significance Index: 12.5200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4295
Cell Significance Index: 20.1900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4153
Cell Significance Index: 79.0300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4104
Cell Significance Index: 48.4000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3606
Cell Significance Index: 325.6200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.3517
Cell Significance Index: 60.0600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.3420
Cell Significance Index: 44.1800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2412
Cell Significance Index: 6.4400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2290
Cell Significance Index: 82.1400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.2090
Cell Significance Index: 5.6900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.2086
Cell Significance Index: 3.8600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1933
Cell Significance Index: 19.1200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1592
Cell Significance Index: 25.8900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1151
Cell Significance Index: 4.0500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1059
Cell Significance Index: 73.2700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0667
Cell Significance Index: 7.6100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0596
Cell Significance Index: 1.2700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0422
Cell Significance Index: 30.9200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0259
Cell Significance Index: 1.9900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0085
Cell Significance Index: 6.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0028
Cell Significance Index: 5.2900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0138
Cell Significance Index: -25.5000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0169
Cell Significance Index: -26.0100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0196
Cell Significance Index: -2.0000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0210
Cell Significance Index: -15.5500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0224
Cell Significance Index: -30.4700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0250
Cell Significance Index: -0.6700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0262
Cell Significance Index: -16.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0284
Cell Significance Index: -17.7600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0487
Cell Significance Index: -0.8200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0508
Cell Significance Index: -28.6500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0596
Cell Significance Index: -27.0600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0624
Cell Significance Index: -1.6400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0781
Cell Significance Index: -4.8000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0782
Cell Significance Index: -8.9600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0880
Cell Significance Index: -4.6200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0888
Cell Significance Index: -7.0300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0973
Cell Significance Index: -20.4900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1061
Cell Significance Index: -30.5200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1137
Cell Significance Index: -2.3800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1170
Cell Significance Index: -17.0100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1527
Cell Significance Index: -2.5600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1742
Cell Significance Index: -4.4500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1915
Cell Significance Index: -9.9800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2178
Cell Significance Index: -5.8300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2270
Cell Significance Index: -26.4500 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2450
Cell Significance Index: -5.6600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.2709
Cell Significance Index: -5.8700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3009
Cell Significance Index: -20.2300 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.3307
Cell Significance Index: -2.6400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3410
Cell Significance Index: -11.8500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.3722
Cell Significance Index: -10.7300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3760
Cell Significance Index: -39.1500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3994
Cell Significance Index: -25.1700 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.4045
Cell Significance Index: -5.9700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4441
Cell Significance Index: -24.9200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4704
Cell Significance Index: -28.8400 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: -0.4869
Cell Significance Index: -0.6300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4968
Cell Significance Index: -7.3400 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.4988
Cell Significance Index: -4.1900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.5167
Cell Significance Index: -5.8700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5342
Cell Significance Index: -23.6300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5462
Cell Significance Index: -17.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5765
Cell Significance Index: -9.8800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.6284
Cell Significance Index: -18.5100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6401
Cell Significance Index: -24.2400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.7061
Cell Significance Index: -20.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 327702612
Symbol: THIK_HUMAN
Name: Acetyl-CoA C-myristoyltransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3194209
Title: Nucleotide sequence of human peroxisomal 3-oxoacyl-CoA thiolase.
PubMed ID: 3194209
PubMed ID: 2726492
Title: Complete cDNA sequence of human foetal liver peroxisomal 3-oxoacyl-CoA thiolase.
PubMed ID: 2726492
PubMed ID: 1679347
Title: Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient.
PubMed ID: 1679347
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2882519
Title: Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency.
PubMed ID: 2882519
PubMed ID: 11734571
Title: Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid.
PubMed ID: 11734571
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22057399
Title: Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7.
PubMed ID: 22057399
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 25538232
Title: Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.
PubMed ID: 25538232
Sequence Information:
- Length: 424
- Mass: 44292
- Checksum: 71B2BBAFA06AE412
- Sequence:
MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN RQCSSGLQAV ASIAGGIRNG SYDIGMACGV ESMSLADRGN PGNITSRLME KEKARDCLIP MGITSENVAE RFGISREKQD TFALASQQKA ARAQSKGCFQ AEIVPVTTTV HDDKGTKRSI TVTQDEGIRP STTMEGLAKL KPAFKKDGST TAGNSSQVSD GAAAILLARR SKAEELGLPI LGVLRSYAVV GVPPDIMGIG PAYAIPVALQ KAGLTVSDVD IFEINEAFAS QAAYCVEKLR LPPEKVNPLG GAVALGHPLG CTGARQVITL LNELKRRGKR AYGVVSMCIG TGMGAAAVFE YPGN
Genular Protein ID: 2951958359
Symbol: A0A140VJX0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 331
- Mass: 34665
- Checksum: 8137A0AC448FBA24
- Sequence:
MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN RQCSSGLQAV ASIAGGIRNG SYDIGMACGI TSENVAERFG ISREKQDTFA LASQQKAARA QSKGCFQAEI VPVTTTVHDD KGTKRSITVT QDEGIRPSTT MEGLAKLKPA FKKDGSTTAG LTVSDVDIFE INEAFASQAA YCVEKLRLPP EKVNPLGGAV ALGHPLGCTG ARQVITLLNE LKRRGKRAYG VVSMCIGTGM GAAAVFEYPG N
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.