ACAA1 | ENSG00000060971 | NCBI 30

Details for: ACAA1

Gene ID: 30

Symbol: ACAA1

Ensembl ID: ENSG00000060971

Description: acetyl-CoA acyltransferase 1

Associated with

Alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
(R-HSA-2046104)
Alpha-linolenic acid (ala) metabolism
(R-HSA-2046106)
Beta-oxidation of very long chain fatty acids
(R-HSA-390247)
Fatty acid metabolism
(R-HSA-8978868)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Neutrophil degranulation
(R-HSA-6798695)
Peroxisomal lipid metabolism
(R-HSA-390918)
Peroxisomal protein import
(R-HSA-9033241)
Protein localization
(R-HSA-9609507)
Tysnd1 cleaves peroxisomal proteins
(R-HSA-9033500)
Acetate coa-transferase activity
(GO:0008775)
Acetyl-coa c-acetyltransferase activity
(GO:0003985)
Acetyl-coa c-acyltransferase activity
(GO:0003988)
Acetyl-coa c-myristoyltransferase activity
(GO:0050633)
Alpha-linolenic acid metabolic process
(GO:0036109)
Bile acid metabolic process
(GO:0008206)
Cytosol
(GO:0005829)
Extracellular region
(GO:0005576)
Fatty acid beta-oxidation
(GO:0006635)
Fatty acid beta-oxidation using acyl-coa oxidase
(GO:0033540)
Membrane
(GO:0016020)
Palmitoyl-coa oxidase activity
(GO:0016401)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Phenylacetate catabolic process
(GO:0010124)
Protein binding
(GO:0005515)
Specific granule lumen
(GO:0035580)
Very long-chain fatty acid metabolic process
(GO:0000038)

Other Information

Proteins

Acetyl-CoA C-myristoyltransferase
A0A140VJX0_HUMAN

Genular Protein ID: 327702612

Symbol: THIK_HUMAN

Name: Acetyl-CoA C-myristoyltransferase

UniProtKB Accession Codes:

P09110 G5E935 Q96CA6

Database IDs:

Citations:

PubMed ID: 3194209

Title: Nucleotide sequence of human peroxisomal 3-oxoacyl-CoA thiolase.

PubMed ID: 3194209

DOI: 10.1093/nar/16.21.10369

PubMed ID: 2726492

Title: Complete cDNA sequence of human foetal liver peroxisomal 3-oxoacyl-CoA thiolase.

PubMed ID: 2726492

DOI: 10.1093/nar/17.9.3588

PubMed ID: 1679347

Title: Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient.

PubMed ID: 1679347

DOI: 10.1016/0167-4781(91)90035-k

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2882519

Title: Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency.

PubMed ID: 2882519

DOI: 10.1073/pnas.84.8.2494

PubMed ID: 11734571

Title: Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid.

PubMed ID: 11734571

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22057399

Title: Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7.

PubMed ID: 22057399

DOI: 10.1074/jbc.m111.301853

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25538232

Title: Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.

PubMed ID: 25538232

DOI: 10.1074/jbc.m114.601575

Sequence Information:

Length: 424
Mass: 44292
Checksum: 71B2BBAFA06AE412
Sequence:

MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT 
PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN 
RQCSSGLQAV ASIAGGIRNG SYDIGMACGV ESMSLADRGN PGNITSRLME KEKARDCLIP 
MGITSENVAE RFGISREKQD TFALASQQKA ARAQSKGCFQ AEIVPVTTTV HDDKGTKRSI 
TVTQDEGIRP STTMEGLAKL KPAFKKDGST TAGNSSQVSD GAAAILLARR SKAEELGLPI 
LGVLRSYAVV GVPPDIMGIG PAYAIPVALQ KAGLTVSDVD IFEINEAFAS QAAYCVEKLR 
LPPEKVNPLG GAVALGHPLG CTGARQVITL LNELKRRGKR AYGVVSMCIG TGMGAAAVFE 
YPGN

Genular Protein ID: 2951958359

Symbol: A0A140VJX0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJX0

Database IDs:

Sequence Information:

Length: 331
Mass: 34665
Checksum: 8137A0AC448FBA24
Sequence:

MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT 
PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN 
RQCSSGLQAV ASIAGGIRNG SYDIGMACGI TSENVAERFG ISREKQDTFA LASQQKAARA 
QSKGCFQAEI VPVTTTVHDD KGTKRSITVT QDEGIRPSTT MEGLAKLKPA FKKDGSTTAG 
LTVSDVDIFE INEAFASQAA YCVEKLRLPP EKVNPLGGAV ALGHPLGCTG ARQVITLLNE 
LKRRGKRAYG VVSMCIGTGM GAAAVFEYPG N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ACAA1

Associated with

Other Information

Nucleotide sequence of human peroxisomal 3-oxoacyl-CoA thiolase. PubMed ID: 3194209

Complete cDNA sequence of human foetal liver peroxisomal 3-oxoacyl-CoA thiolase. PubMed ID: 2726492

Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient. PubMed ID: 1679347

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency. PubMed ID: 2882519

Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid. PubMed ID: 11734571

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Initial characterization of the human central proteome. PubMed ID: 21269460

Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7. PubMed ID: 22057399

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7. PubMed ID: 25538232