Opn4 | ENSMUSG00000021799 | NCBI 30044

Details for: Opn4

Gene ID: 30044

Symbol: Opn4

Ensembl ID: ENSMUSG00000021799

Description: opsin 4 (melanopsin)

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Opsins
(R-MMU-419771)
Signaling by gpcr
(R-MMU-372790)
11-cis retinal binding
(GO:0005502)
Cell projection
(GO:0042995)
Cellular response to light stimulus
(GO:0071482)
Detection of temperature stimulus involved in thermoception
(GO:0050960)
G protein-coupled photoreceptor activity
(GO:0008020)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hyaloid vascular plexus regression
(GO:1990384)
Membrane
(GO:0016020)
Optokinetic behavior
(GO:0007634)
Photoreceptor activity
(GO:0009881)
Phototransduction
(GO:0007602)
Plasma membrane
(GO:0005886)
Regulation of circadian rhythm
(GO:0042752)
Response to stimulus
(GO:0050896)
Retina development in camera-type eye
(GO:0060041)
Rhythmic process
(GO:0048511)
Signal transduction
(GO:0007165)
Sperm head plasma membrane
(GO:1990913)
Thermotaxis
(GO:0043052)
Visual perception
(GO:0007601)

Other Information

Proteins

Melanopsin

Genular Protein ID: 1309718813

Symbol: OPN4_MOUSE

Name: Melanopsin

UniProtKB Accession Codes:

Q9QXZ9 A4QPG3 B2C712

Database IDs:

Citations:

PubMed ID: 10632589

Title: A novel human opsin in the inner retina.

PubMed ID: 10632589

DOI: 10.1523/jneurosci.20-02-00600.2000

PubMed ID: 19793992

Title: Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina.

PubMed ID: 19793992

DOI: 10.1523/jneurosci.2036-09.2009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11834834

Title: Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity.

PubMed ID: 11834834

DOI: 10.1126/science.1069609

PubMed ID: 12808468

Title: Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice.

PubMed ID: 12808468

DOI: 10.1038/nature01761

PubMed ID: 26392540

Title: Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea.

PubMed ID: 26392540

DOI: 10.1073/pnas.1516259112

PubMed ID: 30240620

Title: Impaired Circadian Photoentrainment in Opn5-Null Mice.

PubMed ID: 30240620

DOI: 10.1016/j.isci.2018.08.010

PubMed ID: 31607531

Title: Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin.

PubMed ID: 31607531

DOI: 10.1016/j.cub.2019.08.063

PubMed ID: 30936473

Title: An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.

PubMed ID: 30936473

DOI: 10.1038/s41556-019-0301-x

Sequence Information:

Length: 521
Mass: 57231
Checksum: 50FD1CBB05669DA9
Sequence:

MDSPSGPRVL SSLTQDPSFT TSPALQGIWN GTQNVSVRAQ LLSVSPTTSA HQAAAWVPFP 
TVDVPDHAHY TLGTVILLVG LTGMLGNLTV IYTFCRNRGL RTPANMFIIN LAVSDFLMSV 
TQAPVFFASS LYKKWLFGET GCEFYAFCGA VFGITSMITL TAIAMDRYLV ITRPLATIGR 
GSKRRTALVL LGVWLYALAW SLPPFFGWSA YVPEGLLTSC SWDYMTFTPQ VRAYTMLLFC 
FVFFLPLLII IFCYIFIFRA IRETGRACEG CGESPLRQRR QWQRLQSEWK MAKVALIVIL 
LFVLSWAPYS TVALVAFAGY SHILTPYMSS VPAVIAKASA IHNPIIYAIT HPKYRVAIAQ 
HLPCLGVLLG VSGQRSHPSL SYRSTHRSTL SSQSSDLSWI SGRKRQESLG SESEVGWTDT 
ETTAAWGAAQ QASGQSFCSQ NLEDGELKAS SSPQVQRSKT PKVPGPSTCR PMKGQGARPS 
SLRGDQKGRL AVCTGLSECP HPHTSQFPLA FLEDDVTLRH L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Opn4

Associated with

Other Information

A novel human opsin in the inner retina. PubMed ID: 10632589

Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina. PubMed ID: 19793992

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. PubMed ID: 11834834

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. PubMed ID: 12808468

Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. PubMed ID: 26392540

Impaired Circadian Photoentrainment in Opn5-Null Mice. PubMed ID: 30240620

Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin. PubMed ID: 31607531

An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. PubMed ID: 30936473