pitx2 | ENSDARG00000036194 | NCBI 30164

Details for: pitx2

Gene ID: 30164

Symbol: pitx2

Ensembl ID: ENSDARG00000036194

Description: paired-like homeodomain 2

Associated with

Anatomical structure morphogenesis
(GO:0009653)
Camera-type eye development
(GO:0043010)
Camera-type eye morphogenesis
(GO:0048593)
Closure of optic fissure
(GO:0061386)
Cornea development in camera-type eye
(GO:0061303)
Determination of digestive tract left/right asymmetry
(GO:0071907)
Determination of left/right asymmetry in diencephalon
(GO:0035462)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic camera-type eye morphogenesis
(GO:0048596)
Embryonic cranial skeleton morphogenesis
(GO:0048701)
Embryonic heart tube left/right pattern formation
(GO:0060971)
Embryonic viscerocranium morphogenesis
(GO:0048703)
Epithalamus development
(GO:0021538)
Face morphogenesis
(GO:0060325)
Habenula development
(GO:0021986)
Iris morphogenesis
(GO:0061072)
Mesendoderm development
(GO:0048382)
Nucleus
(GO:0005634)
Odontogenesis
(GO:0042476)
Prechordal plate formation
(GO:0021501)
Regulation of convergent extension involved in gastrulation
(GO:1904103)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Regulation of vascular permeability
(GO:0043114)
Retinoic acid receptor signaling pathway
(GO:0048384)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)

Other Information

Proteins

Pituitary homeobox 2

Genular Protein ID: 1621898758

Symbol: PITX2_DANRE

Name: Pituitary homeobox 2

UniProtKB Accession Codes:

Q9W5Z2 Q568C4 Q9W5Z1

Database IDs:

Citations:

PubMed ID: 10521397

Title: Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.

PubMed ID: 10521397

DOI: 10.1101/gad.13.19.2527

PubMed ID: 10500184

Title: Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the Shh and retinoic acid pathways in the control of Lefty-1.

PubMed ID: 10500184

DOI: 10.1073/pnas.96.20.11376

PubMed ID: 10662647

Title: Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms.

PubMed ID: 10662647

DOI: 10.1242/dev.127.5.1081

Sequence Information:

Length: 314
Mass: 35187
Checksum: 52D0F7855664A6B5
Sequence:

MTSMKDPLSL DHHHHNHHVT GSKHAPLSMA SSLQPLQRSV DSKHRLDVHT VSDTSSPESV 
EKEKGQSKNE DSNDDPSKKK RQRRQRTHFT SQQLQELEAT FQRNRYPDMS TREEIAVWTN 
LTEARVRVWF KNRRAKWRKR ERNQQAELCK NGFGPQFNGL MQPYDDMYPS YTYNNWAAKG 
LTSASLSTKS FPFFNSMNVN PLSSQTMFSP PNSISSMSMS SSMVPSAVTG VPGSSLNSLN 
NLNNLSNPSL NSGVPTPACP YAPPTPPYVY RDTCNSSLAS LRLKAKQHSS FGYASVQNPA 
SNLSACQYAV DRPV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.