Details for: smo

Gene ID: 30225

Symbol: smo

Ensembl ID: ENSDARG00000002952

Description: smoothened, frizzled class receptor

Associated with

Other Information

Genular Protein ID: 4068104083

Symbol: SMO_DANRE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11493557

Title: Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity.

PubMed ID: 11493557

DOI: 10.1242/dev.128.12.2385

PubMed ID: 11566855

Title: Zebrafish smoothened functions in ventral neural tube specification and axon tract formation.

PubMed ID: 11566855

DOI: 10.1242/dev.128.18.3497

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 12606279

Title: Multiple roles for Hedgehog signaling in zebrafish pituitary development.

PubMed ID: 12606279

DOI: 10.1016/s0012-1606(02)00027-1

PubMed ID: 12588855

Title: Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle.

PubMed ID: 12588855

DOI: 10.1242/dev.00360

PubMed ID: 16136078

Title: Vertebrate Smoothened functions at the primary cilium.

PubMed ID: 16136078

DOI: 10.1038/nature04117

PubMed ID: 16481351

Title: Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development.

PubMed ID: 16481351

DOI: 10.1242/dev.02281

PubMed ID: 17597528

Title: Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish.

PubMed ID: 17597528

DOI: 10.1186/1471-213x-7-75

PubMed ID: 18423594

Title: Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum.

PubMed ID: 18423594

DOI: 10.1016/j.ydbio.2008.03.016

PubMed ID: 18842815

Title: Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential.

PubMed ID: 18842815

DOI: 10.1242/dev.024083

PubMed ID: 19464178

Title: The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling.

PubMed ID: 19464178

DOI: 10.1016/j.cub.2009.04.053

PubMed ID: 20193674

Title: Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fate.

PubMed ID: 20193674

DOI: 10.1016/j.ydbio.2010.02.028

PubMed ID: 24504339

Title: Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling.

PubMed ID: 24504339

DOI: 10.1242/dev.100313

PubMed ID: 34087472

Title: The development of zebrafish pancreas affected by deficiency of Hedgehog signaling.

PubMed ID: 34087472

DOI: 10.1016/j.gep.2021.119185

PubMed ID: 24171105

Title: Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.

PubMed ID: 24171105

DOI: 10.7554/elife.01340

Sequence Information:

  • Length: 822
  • Mass: 93059
  • Checksum: C95CF5F5E864590D
  • Sequence:
  • MSSKRPCSIV GSFWMLWIWT ATSMVARAVI LHPNETIFND FCKKSTTCEV LKYNTCLGSP 
    LPYTHTSLIL AEDSETQEEA FEKLAMWSGL RNAPRCWAVI QPLLCAVYMP KCENGKVELP 
    SQHLCQATRN PCSIVERERG WPNFLKCENK EQFPKGCQNE VQKLKFNTSG QCEAPLVKTD 
    IQASWYKDVE GCGIQCDNPL FTEDEHSDMH SYIAVFGTIT LLCTFFTLAT FLADWKNSNR 
    YPAVILFYVN ACFFIGSIGW LAQFMDGARN EIVCKSDNTM RLGEPSSTET LSCVIIFVIV 
    YYSLMSGVIW FVMLTYAWHT SFKALGTTHQ PLSGKTSYFH LVTWSIPFIL TVAILANSQV 
    DADSVSGICF VGYRYYEYRA GFVLAPIGFV LVIGGYFLIR GVMTLFSIKS NHPGLLSEKA 
    ASKINETMLR LGIFGFLAFG FVLITFGCHF YDFFNQAEWE RSFREYVLCE ANVTIAHQTN 
    KPIPECAIKN RPSLLVGKIN LFSMFGTGIA MSTWVWTKAT ILIWKRTWFR IIGRSDDEPK 
    RIKKSKMIAK AFSKRKELQK DPEKELSFSM HTVSHEGPVA GINFDLNEPS IEMSSAWAQH 
    VTKMVARRGA ILPQDISVTP TGTPIPPPEE RNKLWMVEAE ISPEMMKRKK KKKKRRKEVR 
    PAGPAADEGN PAYHRREFGP SAVPRLPKLP GHRSLVANLW EQQRQQQEEQ DMLPGAFPEF 
    RPSCPLPYQD RYGGLGYLRN KPSSLPLANP LTLRDSMQGD LSHFQQSSWQ PKGVFRHLGQ 
    EASMMDVGRT AVVPRADGRR GVQIHSRTNL MDAELLDADS DF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.