Details for: her3

Gene ID: 30289

Symbol: her3

Ensembl ID: ENSDARG00000076857

Description: hairy-related 3

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of neurogenesis
    (GO:0050768)
  • Nucleus
    (GO:0005634)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 3657562322

Symbol: Q90465_DANRE

Name: N/A

UniProtKB Accession Codes:

Q90465

Database IDs:

ARBA 2 CTD 1 EMBL 4 GO 10 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 Pfam 1 Proteomes 2 RefSeq 2 SAM 1 SMART 2 SUPFAM 1 ZFIN 2

Citations:

PubMed ID: 10101116

Title: her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling.

PubMed ID: 10101116

PubMed ID: 12160468

Title: Comparative analysis of somitogenesis related genes of the hairy/Enhancer of split class in Fugu and zebrafish.

PubMed ID: 12160468

PubMed ID: 15169758

Title: her3, a zebrafish member of the hairy-E(spl) family, is repressed by Notch signalling.

PubMed ID: 15169758

DOI: 10.1242/dev.01167

PubMed ID: 15590746

Title: Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair.

PubMed ID: 15590746

DOI: 10.1242/dev.01525

PubMed ID: 15716337

Title: Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm.

PubMed ID: 15716337

PubMed ID: 21586122

Title: The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish.

PubMed ID: 21586122

PubMed ID: 22808219

Title: Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.

PubMed ID: 22808219

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 24056933

Title: Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition.

PubMed ID: 24056933

PubMed ID: 23950494

Title: Pou5f1 transcription factor controls zygotic gene activation in vertebrates.

PubMed ID: 23950494

PubMed ID: 25446033

Title: The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis.

PubMed ID: 25446033

Sequence Information:

  • Length: 229
  • Mass: 26145
  • Checksum: 03312C7C556859A0
  • Sequence:
    • MAAASNSAAT AKPQNVKKVS KPLMEKKRRA RINKCLNQLK SLLESACSNN IRKRKLEKAD 
ILELTVKHLR HLQNTKRGLS KACDSAEYHA GYRSCLNTVS HYLRASDTDR DSRSIMLTNL 
TSGLNHNRVP DFSTVESDPA LIFTLPSTLR RPHKVPIRTD VSYSSFQQTA ERKVCLMPKR 
TEIGDSDRMS LDAALRSQES KKAETTHFRP KDLKVIECCI FKQNYWRPW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.