cyp26a1 | ENSDARG00000033999 | NCBI 30381

Details for: cyp26a1

Gene ID: 30381

Symbol: cyp26a1

Ensembl ID: ENSDARG00000033999

Description: cytochrome P450, family 26, subfamily A, polypeptide 1

Associated with

Biological oxidations
(R-DRE-211859)
Cytochrome p450 - arranged by substrate type
(R-DRE-211897)
Metabolism
(R-DRE-1430728)
Phase i - functionalization of compounds
(R-DRE-211945)
Ra biosynthesis pathway
(R-DRE-5365859)
Signaling by nuclear receptors
(R-DRE-9006931)
Signaling by retinoic acid
(R-DRE-5362517)
Signal transduction
(R-DRE-162582)
Vitamins
(R-DRE-211916)
1-hydroxy-2-naphthoate hydroxylase activity
(GO:0018637)
1-hydroxy-2-oxolimonene 1,2-monooxygenase activity
(GO:0018646)
1-methylnaphthalene hydroxylase activity
(GO:0034534)
2-hydroxy-phenylacetate hydroxylase activity
(GO:0018654)
2-methylnaphthalene hydroxylase activity
(GO:0034526)
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity
(GO:0043719)
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-coa 1,2-monooxygenase activity
(GO:0018655)
3,5-xylenol methylhydroxylase activity
(GO:0018630)
3-hsa hydroxylase activity
(GO:0034819)
3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
(GO:0018653)
4-chlorobenzaldehyde oxidase activity
(GO:0018471)
4-hydroxypyridine-3-hydroxylase activity
(GO:0034894)
6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
(GO:0018641)
Alpha-pinene monooxygenase [nadh] activity
(GO:0018634)
Anterior/posterior pattern specification involved in pronephros development
(GO:0034672)
Atrial cardiac muscle cell development
(GO:0055014)
Bisphenol a hydroxylase a activity
(GO:0034560)
Blood vessel development
(GO:0001568)
Brain morphogenesis
(GO:0048854)
Branched-chain dodecylbenzene sulfonate monooxygenase activity
(GO:0034802)
Carbon disulfide oxygenase activity
(GO:0018643)
Cellular response to vitamin a
(GO:0071299)
Chlorophenol 4-monooxygenase activity
(GO:0018642)
Dimethyl sulfide monooxygenase activity
(GO:0018633)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Forebrain anterior/posterior pattern specification
(GO:0021797)
Heart development
(GO:0007507)
Heme binding
(GO:0020037)
Hindbrain development
(GO:0030902)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Isobutylamine n-hydroxylase activity
(GO:0034791)
Limonene monooxygenase activity
(GO:0019113)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Mesodermal-endodermal cell signaling
(GO:0003131)
Metal ion binding
(GO:0046872)
Midbrain-hindbrain boundary development
(GO:0030917)
Monooxygenase activity
(GO:0004497)
Outflow tract morphogenesis
(GO:0003151)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, nad(p)h as one donor, and incorporation of one atom of oxygen
(GO:0016709)
Pancreas development
(GO:0031016)
Phenanthrene 1,2-monooxygenase activity
(GO:0018647)
Phenanthrene 3,4-monooxygenase activity
(GO:0018656)
Phenanthrene 9,10-monooxygenase activity
(GO:0018636)
Phenylacetate hydroxylase activity
(GO:0018631)
Retinal metabolic process
(GO:0042574)
Retinoic acid 4-hydroxylase activity
(GO:0008401)
Retinoic acid catabolic process
(GO:0034653)
Retinoic acid metabolic process
(GO:0042573)
Retinoic acid receptor signaling pathway involved in somitogenesis
(GO:0090242)
Rhombomere 4 morphogenesis
(GO:0021661)
Somitogenesis
(GO:0001756)
Sterol metabolic process
(GO:0016125)
Styrene monooxygenase activity
(GO:0018650)
Tetrahydrofuran hydroxylase activity
(GO:0018649)
Thalianol hydroxylase activity
(GO:0080014)
Tocotrienol omega-hydroxylase activity
(GO:0052872)
Toluene-4-sulfonate monooxygenase activity
(GO:0018651)
Toluene 4-monooxygenase activity
(GO:0018638)
Vasculature development
(GO:0001944)
Xylene monooxygenase activity
(GO:0018639)

Other Information

Proteins

Q7SXV4_DANRE

Genular Protein ID: 1152196175

Symbol: Q7SXV4_DANRE

Name: N/A

UniProtKB Accession Codes:

Q7SXV4 A0A8N7UZH1

Database IDs:

Citations:

PubMed ID: 9228017

Title: cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.

PubMed ID: 9228017

DOI: 10.1074/jbc.272.30.18538

PubMed ID: 10545224

Title: A second CYP26 P450 in humans and zebrafish: CYP26B1.

PubMed ID: 10545224

PubMed ID: 11731487

Title: A gene expression screen in zebrafish embryogenesis.

PubMed ID: 11731487

PubMed ID: 12183385

Title: Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm.

PubMed ID: 12183385

PubMed ID: 12880634

Title: From cells to circuits: development of the zebrafish spinal cord.

PubMed ID: 12880634

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 29972792

Title: Spatial Fold Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish.

PubMed ID: 29972792

PubMed ID: 29874129

Title: Retinoic acid signaling is essential for maintenance of the blood-retinal barrier.

PubMed ID: 29874129

PubMed ID: 30400013

Title: Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia.

PubMed ID: 30400013

PubMed ID: 30472261

Title: Znfl1s are essential for patterning the anterior-posterior axis of zebrafish posterior hindbrain by acting as direct target genes of retinoic acid.

PubMed ID: 30472261

PubMed ID: 30721228

Title: Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors.

PubMed ID: 30721228

Sequence Information:

Length: 492
Mass: 56253
Checksum: 4A2AD535B329AE78
Sequence:

MGLYTLMVTF LCTIVLPVLL FLAAVKLWEM LMIRRVDPNC RSPLPPGTMG LPFIGETLQL 
ILQRRKFLRM KRQKYGCIYK THLFGNPTVR VMGADNVRQI LLGEHKLVSV QWPASVRTIL 
GSDTLSNVHG VQHKNKKKAI MRAFSRDALE HYIPVIQQEV KSAIQEWLQK DSCVLVYPEM 
KKLMFRIAMR ILLGFEPEQI KTDEQELVEA FEEMIKNLFS LPIDVPFSGL YRGLRARNFI 
HSKIEENIRK KIQDDDNENE QKYKDALQLL IENSRRSDEP FSLQAMKEAA TELLFGGHET 
TASTATSLVM FLGLNTEVVQ KVREEVQEKV EMGMYTPGKG LSMELLDQLK YTGCVIKETL 
RINPPVPGGF RVALKTFELN GYQIPKGWNV IYSICDTHDV ADVFPNKDEF QPERFMSKGL 
EDGSRFNYIP FGGGSRMCVG KEFAKVLLKI FLVELTQHCN WILSNGPPTM KTGPTVYPVD 
NLPTKFTSYV RN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: cyp26a1

Associated with

Other Information

cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. PubMed ID: 9228017

A second CYP26 P450 in humans and zebrafish: CYP26B1. PubMed ID: 10545224

A gene expression screen in zebrafish embryogenesis. PubMed ID: 11731487

Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. PubMed ID: 12183385

From cells to circuits: development of the zebrafish spinal cord. PubMed ID: 12880634

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

Spatial Fold Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish. PubMed ID: 29972792

Retinoic acid signaling is essential for maintenance of the blood-retinal barrier. PubMed ID: 29874129

Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia. PubMed ID: 30400013

Znfl1s are essential for patterning the anterior-posterior axis of zebrafish posterior hindbrain by acting as direct target genes of retinoic acid. PubMed ID: 30472261

Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors. PubMed ID: 30721228