tcf7l1a | ENSDARG00000038159 | NCBI 30523

Details for: tcf7l1a

Gene ID: 30523

Symbol: tcf7l1a

Ensembl ID: ENSDARG00000038159

Description: transcription factor 7 like 1a

Associated with

Deactivation of the beta-catenin transactivating complex
(R-DRE-3769402)
Degradation of beta-catenin by the destruction complex
(R-DRE-195253)
Formation of the beta-catenin:tcf transactivating complex
(R-DRE-201722)
Repression of wnt target genes
(R-DRE-4641265)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
Beta-catenin-tcf complex
(GO:1990907)
Canonical wnt signaling pathway
(GO:0060070)
Cell proliferation in dorsal spinal cord
(GO:0010456)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic camera-type eye formation
(GO:0060900)
Embryonic camera-type eye morphogenesis
(GO:0048596)
Endothelial cell fate specification
(GO:0060847)
Forebrain development
(GO:0030900)
Generation of neurons
(GO:0048699)
Head morphogenesis
(GO:0060323)
Heart development
(GO:0007507)
Midbrain development
(GO:0030901)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nucleus
(GO:0005634)
Positive regulation of cell population proliferation
(GO:0008284)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rostrocaudal neural tube patterning
(GO:0021903)
Spinal cord dorsal/ventral patterning
(GO:0021513)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Transcription factor 7-like 1-A

Genular Protein ID: 1673115765

Symbol: T7L1A_DANRE

Name: Transcription factor 7-like 1-A

UniProtKB Accession Codes:

Q9YHE8

Database IDs:

Citations:

PubMed ID: 9784608

Title: Function of zebrafish beta-catenin and TCF-3 in dorsoventral patterning.

PubMed ID: 9784608

DOI: 10.1016/s0925-4773(98)00132-4

PubMed ID: 11057671

Title: Repressor activity of Headless/Tcf3 is essential for vertebrate head formation.

PubMed ID: 11057671

DOI: 10.1038/35038097

PubMed ID: 11784107

Title: A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development.

PubMed ID: 11784107

DOI: 10.1006/dbio.2001.0515

PubMed ID: 12642497

Title: Two tcf3 genes cooperate to pattern the zebrafish brain.

PubMed ID: 12642497

DOI: 10.1242/dev.00402

PubMed ID: 15151990

Title: nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development.

PubMed ID: 15151990

DOI: 10.1242/dev.01171

PubMed ID: 25371059

Title: Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/beta-catenin pathway.

PubMed ID: 25371059

DOI: 10.1038/ncomms6368

Sequence Information:

Length: 560
Mass: 61459
Checksum: DC35C50EA4D61232
Sequence:

MPQLNGGGGD DLGANDELIS FKDEGEQEEK ISENVSSERD LDEVKSSLVN ESENNSSSSD 
SEQTDRRPRP RPDLESYEKQ REYFAEALRR QQDGGFFKGP PYAGYPFLMI PDITNPYLSN 
GSLSPSTRTY LQMKWPLLDV PASAALKDSR SPTPGHLSNK VPVVQHPHHV HPLTPLITYS 
NEHFSPGTPP SHLSPEILDP KTGIPRTPHP SELSPYYPLS PGAVGQIPHP LGWLVPQQGQ 
HMYSIPPGGF RHPYPALAMN ASMSSLVSSR FSPHMVPHPP HGLHQTGIPH PAIVSPAIKQ 
EPNGESPSNS THGKPSVPVK KEEEKKPHIK KPLNAFMLYM KEMRAKVVAE CTLKESAAIN 
QILGRRWHSL SREEQAKYYE LARKERQLHS QLYPGWSARD NYGKRKKRKR DCKSDSPSES 
NFSPQPKKQC VPYLSSEKMC DSPTSSHGSM LDSPATPSAA LASPAAPAAT HSEQAQPLSL 
TTKPEGRAHH NHPHFPLPGK SSGSGSGSSM ALHSLSRPIP FTSLPPSLLG PNSPFHQAAL 
HSHHALLQTQ PLSLVTKSVE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: tcf7l1a

Associated with

Other Information

Function of zebrafish beta-catenin and TCF-3 in dorsoventral patterning. PubMed ID: 9784608

Repressor activity of Headless/Tcf3 is essential for vertebrate head formation. PubMed ID: 11057671

A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development. PubMed ID: 11784107

Two tcf3 genes cooperate to pattern the zebrafish brain. PubMed ID: 12642497

nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development. PubMed ID: 15151990