smad2 | ENSDARG00000006389 | NCBI 30639

Details for: smad2

Gene ID: 30639

Symbol: smad2

Ensembl ID: ENSDARG00000006389

Description: SMAD family member 2

Associated with

Deubiquitination
(R-DRE-5688426)
Downregulation of smad2/3:smad4 transcriptional activity
(R-DRE-2173795)
Downregulation of tgf-beta receptor signaling
(R-DRE-2173788)
Gene expression (transcription)
(R-DRE-74160)
Generic transcription pathway
(R-DRE-212436)
Metabolism of proteins
(R-DRE-392499)
Post-translational protein modification
(R-DRE-597592)
Rna polymerase ii transcription
(R-DRE-73857)
Signaling by activin
(R-DRE-1502540)
Signaling by tgf-beta receptor complex
(R-DRE-170834)
Signaling by tgfb family members
(R-DRE-9006936)
Signal transduction
(R-DRE-162582)
Tgf-beta receptor signaling activates smads
(R-DRE-2173789)
Transcriptional activity of smad2/smad3:smad4 heterotrimer
(R-DRE-2173793)
Ub-specific processing proteases
(R-DRE-5689880)
Activin receptor signaling pathway
(GO:0032924)
Anatomical structure morphogenesis
(GO:0009653)
Cell differentiation
(GO:0030154)
Chromatin
(GO:0000785)
Convergent extension involved in axis elongation
(GO:0060028)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic pattern specification
(GO:0009880)
Heteromeric smad protein complex
(GO:0071144)
I-smad binding
(GO:0070411)
Intracellular signal transduction
(GO:0035556)
Metal ion binding
(GO:0046872)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural plate anterior/posterior regionalization
(GO:0021999)
Nodal signaling pathway
(GO:0038092)
Nucleus
(GO:0005634)
Positive regulation of oocyte development
(GO:0060282)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Smad protein signal transduction
(GO:0060395)
Transcription regulator complex
(GO:0005667)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)

Other Information

Proteins

Mothers against decapentaplegic homolog 2
A0A8M2B2F4_DANRE

Genular Protein ID: 1616908950

Symbol: SMAD2_DANRE

Name: Mothers against decapentaplegic homolog 2

UniProtKB Accession Codes:

Q9I9P9 Q4V964 Q9PUN4

Database IDs:

Citations:

PubMed ID: 10525190

Title: Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of Smad1 and Smad5 is required for specific function in the embryo.

PubMed ID: 10525190

DOI: 10.1016/s0925-4773(99)00173-2

PubMed ID: 10767528

Title: Cloning and characterization of zebrafish smad2, smad3 and smad4.

PubMed ID: 10767528

DOI: 10.1016/s0378-1119(00)00056-1

Sequence Information:

Length: 468
Mass: 52453
Checksum: 464F4EFDF01D3270
Sequence:

MSSILPFTPP VVKRLLGWKK SASGSSGAGG GGEQNGQEEK WCEKAVKSLV KKLKKTGQLD 
ELEKAITTQN RNTKCVTIPS NCSEIWGLST PNTIEQWDTS GLYSYPDQTR SLDGRLQVSH 
RKGLPHVIYC RLWRWPDLHS HHELRAIETC EYAFNLKKDE VCVNPYHYQR VETPVLPPVL 
VPRHTEILTE LPPLDDYTNS IPENTNFPTG IEPPNNYIPE TPPPGYISED GEASDQQMNQ 
SMDTGSPAEL SPSTLSPVNH GMDLQPVTYS EPAFWCSIAY YELNQRVGET FHASQPSLTV 
DGFTDPSNSE RFCLGLLSNV NRNATVEMTR RHIGRGVRLY YIGGEVFAEC LSDSAIFVQS 
PNCNQRYGWH PATVCKIPPG CNLKIFNNQE FAALLAQSVN QGFEAVYQLT RMCTIRMSFV 
KGWGAEYRRQ TVTSTPCWIE LHLNGPLQWL DKVLTQMGSP SVRCSSMS

Genular Protein ID: 2133012690

Symbol: A0A8M2B2F4_DANRE

Name: N/A

UniProtKB Accession Codes:

A0A8M2B2F4

Database IDs:

Citations:

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

Sequence Information:

Length: 464
Mass: 52049
Checksum: E5812894E252E273
Sequence:

MSSILPFTPP VVKRLLGWKK SASGSSGAGG GGEQNGQEEK WCEKAVKSLV KKLKKTGQLD 
ELEKAITTQN RNTKCVTIPS NCSEIWGLST PNTIEQWDTS GLYSYPDQTR SLDGRLQVSH 
RKGLPHVIYC RLWRWPDLHS HHELRAIETC EYAFNLKKDE VCVNPYHYQR VETPVLPPVL 
VPRHTEILTE LPPLDDYTNS IPENTNFPTG IEPPNNYIPE TPPPGYISED GEASDQQMNQ 
SSPAELSPST LSPVNHGMDL QPVTYSEPAF WCSIAYYELN QRVGETFHAS QPSLTVDGFT 
DPSNSERFCL GLLSNVNRNA TVEMTRRHIG RGVRLYYIGG EVFAECLSDS AIFVQSPNCN 
QRYGWHPATV CKIPPGCNLK IFNNQEFAAL LAQSVNQGFE AVYQLTRMCT IRMSFVKGWG 
AEYRRQTVTS TPCWIELHLN GPLQWLDKVL TQMGSPSVRC SSMS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.