psme2 | ENSDARG00000033144 | NCBI 30647

Details for: psme2

Gene ID: 30647

Symbol: psme2

Ensembl ID: ENSDARG00000033144

Description: proteasome activator subunit 2

Associated with

Abc-family proteins mediated transport
(R-DRE-382556)
Activation of nf-kappab in b cells
(R-DRE-1169091)
Adaptive immune system
(R-DRE-1280218)
Antigen processing-cross presentation
(R-DRE-1236975)
Antigen processing: ubiquitination & proteasome degradation
(R-DRE-983168)
Assembly of the pre-replicative complex
(R-DRE-68867)
Asymmetric localization of pcp proteins
(R-DRE-4608870)
Auf1 (hnrnp d0) binds and destabilizes mrna
(R-DRE-450408)
Autodegradation of the e3 ubiquitin ligase cop1
(R-DRE-349425)
Beta-catenin independent wnt signaling
(R-DRE-3858494)
Cdk-mediated phosphorylation and removal of cdc6
(R-DRE-69017)
Cell cycle
(R-DRE-1640170)
Cell cycle, mitotic
(R-DRE-69278)
Cell cycle checkpoints
(R-DRE-69620)
Cellular responses to stimuli
(R-DRE-8953897)
Cellular responses to stress
(R-DRE-2262752)
Cellular response to chemical stress
(R-DRE-9711123)
Class i mhc mediated antigen processing & presentation
(R-DRE-983169)
Cross-presentation of soluble exogenous antigens (endosomes)
(R-DRE-1236978)
Cyclin a:cdk2-associated events at s phase entry
(R-DRE-69656)
Cyclin e associated events during g1/s transition
(R-DRE-69202)
Degradation of axin
(R-DRE-4641257)
Degradation of dvl
(R-DRE-4641258)
Degradation of gli1 by the proteasome
(R-DRE-5610780)
Deubiquitination
(R-DRE-5688426)
Dna replication
(R-DRE-69306)
Dna replication pre-initiation
(R-DRE-69002)
Downstream signaling events of b cell receptor (bcr)
(R-DRE-1168372)
Fbxl7 down-regulates aurka during mitotic entry and in early mitosis
(R-DRE-8854050)
G1/s dna damage checkpoints
(R-DRE-69615)
G1/s transition
(R-DRE-69206)
G2/m checkpoints
(R-DRE-69481)
G2/m transition
(R-DRE-69275)
Gene expression (transcription)
(R-DRE-74160)
Generic transcription pathway
(R-DRE-212436)
Gli3 is processed to gli3r by the proteasome
(R-DRE-5610785)
Gsk3b and btrc:cul1-mediated-degradation of nfe2l2
(R-DRE-9762114)
Hedgehog 'off' state
(R-DRE-5610787)
Hedgehog 'on' state
(R-DRE-5632684)
Hedgehog ligand biogenesis
(R-DRE-5358346)
Immune system
(R-DRE-168256)
Intracellular signaling by second messengers
(R-DRE-9006925)
Keap1-nfe2l2 pathway
(R-DRE-9755511)
Mapk6/mapk4 signaling
(R-DRE-5687128)
Mapk family signaling cascades
(R-DRE-5683057)
Metabolism
(R-DRE-1430728)
Metabolism of amino acids and derivatives
(R-DRE-71291)
Metabolism of polyamines
(R-DRE-351202)
Metabolism of proteins
(R-DRE-392499)
Metabolism of rna
(R-DRE-8953854)
Mitotic g1 phase and g1/s transition
(R-DRE-453279)
Mitotic g2-g2/m phases
(R-DRE-453274)
Neddylation
(R-DRE-8951664)
Nuclear events mediated by nfe2l2
(R-DRE-9759194)
P53-dependent g1 dna damage response
(R-DRE-69563)
P53-dependent g1/s dna damage checkpoint
(R-DRE-69580)
Pcp/ce pathway
(R-DRE-4086400)
Pip3 activates akt signaling
(R-DRE-1257604)
Post-translational protein modification
(R-DRE-597592)
Pten regulation
(R-DRE-6807070)
Regulation of mrna stability by proteins that bind au-rich elements
(R-DRE-450531)
Regulation of ornithine decarboxylase (odc)
(R-DRE-350562)
Regulation of pten stability and activity
(R-DRE-8948751)
Regulation of runx2 expression and activity
(R-DRE-8939902)
Regulation of runx3 expression and activity
(R-DRE-8941858)
Rna polymerase ii transcription
(R-DRE-73857)
Runx1 regulates transcription of genes involved in differentiation of hscs
(R-DRE-8939236)
Scf(skp2)-mediated degradation of p27/p21
(R-DRE-187577)
Signaling by hedgehog
(R-DRE-5358351)
Signaling by the b cell receptor (bcr)
(R-DRE-983705)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
S phase
(R-DRE-69242)
Stabilization of p53
(R-DRE-69541)
Switching of origins to a post-replicative state
(R-DRE-69052)
Synthesis of dna
(R-DRE-69239)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-DRE-8852276)
Transcriptional regulation by runx1
(R-DRE-8878171)
Transcriptional regulation by runx2
(R-DRE-8878166)
Transcriptional regulation by runx3
(R-DRE-8878159)
Transport of small molecules
(R-DRE-382551)
Ub-specific processing proteases
(R-DRE-5689880)
Ubiquitin-dependent degradation of cyclin d
(R-DRE-75815)
Uch proteinases
(R-DRE-5689603)
Cytoplasm
(GO:0005737)
Endopeptidase activator activity
(GO:0061133)
Nucleoplasm
(GO:0005654)
Positive regulation of endopeptidase activity
(GO:0010950)
Proteasome activator complex
(GO:0008537)
Proteasome complex
(GO:0000502)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Regulation of proteasomal protein catabolic process
(GO:0061136)

Other Information

Proteins

Q9PUC4_DANRE

Genular Protein ID: 3038504088

Symbol: Q9PUC4_DANRE

Name: N/A

UniProtKB Accession Codes:

Q9PUC4 Q6NXB3

Database IDs:

Citations:

PubMed ID: 10849367

Title: Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish.

PubMed ID: 10849367

DOI: 10.1046/j.1365-3083.2000.00728.x

PubMed ID: 14597164

Title: Cloning and sequence analysis of cDNA for the proteasome activator PA28-beta subunit of flounder (Paralichthys olivaceus).

PubMed ID: 14597164

DOI: 10.1016/j.molimm.2003.08.005

PubMed ID: 16901544

Title: Molecular cloning of proteasome activator PA28-beta subunit of large yellow croaker (Pseudosciana crocea) and its coordinated up-regulation with MHC class I alpha-chain and beta 2-microglobulin in poly I:C-treated fish.

PubMed ID: 16901544

DOI: 10.1016/j.molimm.2006.06.024

PubMed ID: 20353558

Title: Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation.

PubMed ID: 20353558

PubMed ID: 22805612

Title: RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish.

PubMed ID: 22805612

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 27409813

Title: Unexpected role of interferon-gamma in regulating neuronal connectivity and social behaviour.

PubMed ID: 27409813

PubMed ID: 28698226

Title: Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.

PubMed ID: 28698226

PubMed ID: 27899647

Title: Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors.

PubMed ID: 27899647

PubMed ID: 29692779

Title: RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways.

PubMed ID: 29692779

PubMed ID: 30728369

Title: Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish.

PubMed ID: 30728369

Sequence Information:

Length: 244
Mass: 27719
Checksum: 6734666B41C04D8A
Sequence:

MSKANVLKLN SDNAVRIENY RQSLYKQAED LFSNYIPLKI SHLDNLLKGD EFSITDLSSL 
HAPLDIPIPD PPAPEDEEME TDKNEDDEKK KKAPKCGFIK GNERIVKLLD IVKPEIMGLK 
ETCITVSCWI AHLIPKIEDG NDFGVAIQEK ILERITAVKT KVEGFQTNIN KYFSERGDAV 
AKASKDTHVM DYRSLVHEKD EAAYSEIRVI VLDIRGFYAE LYDVISKNLE KVTNPKGEEK 
PSMY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: psme2

Associated with

Other Information

Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish. PubMed ID: 10849367

Cloning and sequence analysis of cDNA for the proteasome activator PA28-beta subunit of flounder (Paralichthys olivaceus). PubMed ID: 14597164

Molecular cloning of proteasome activator PA28-beta subunit of large yellow croaker (Pseudosciana crocea) and its coordinated up-regulation with MHC class I alpha-chain and beta 2-microglobulin in poly I:C-treated fish. PubMed ID: 16901544

Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. PubMed ID: 20353558

RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish. PubMed ID: 22805612

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

Unexpected role of interferon-gamma in regulating neuronal connectivity and social behaviour. PubMed ID: 27409813

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. PubMed ID: 28698226

Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors. PubMed ID: 27899647

RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways. PubMed ID: 29692779

Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. PubMed ID: 30728369