psme1 | ENSDARG00000002165 | NCBI 30648

Details for: psme1

Gene ID: 30648

Symbol: psme1

Ensembl ID: ENSDARG00000002165

Description: proteasome activator subunit 1

Associated with

Abc-family proteins mediated transport
(R-DRE-382556)
Activation of nf-kappab in b cells
(R-DRE-1169091)
Adaptive immune system
(R-DRE-1280218)
Antigen processing-cross presentation
(R-DRE-1236975)
Antigen processing: ubiquitination & proteasome degradation
(R-DRE-983168)
Assembly of the pre-replicative complex
(R-DRE-68867)
Asymmetric localization of pcp proteins
(R-DRE-4608870)
Auf1 (hnrnp d0) binds and destabilizes mrna
(R-DRE-450408)
Autodegradation of the e3 ubiquitin ligase cop1
(R-DRE-349425)
Beta-catenin independent wnt signaling
(R-DRE-3858494)
Cdk-mediated phosphorylation and removal of cdc6
(R-DRE-69017)
Cell cycle
(R-DRE-1640170)
Cell cycle, mitotic
(R-DRE-69278)
Cell cycle checkpoints
(R-DRE-69620)
Cellular responses to stimuli
(R-DRE-8953897)
Cellular responses to stress
(R-DRE-2262752)
Cellular response to chemical stress
(R-DRE-9711123)
Class i mhc mediated antigen processing & presentation
(R-DRE-983169)
Cross-presentation of soluble exogenous antigens (endosomes)
(R-DRE-1236978)
Cyclin a:cdk2-associated events at s phase entry
(R-DRE-69656)
Cyclin e associated events during g1/s transition
(R-DRE-69202)
Degradation of axin
(R-DRE-4641257)
Degradation of dvl
(R-DRE-4641258)
Degradation of gli1 by the proteasome
(R-DRE-5610780)
Deubiquitination
(R-DRE-5688426)
Dna replication
(R-DRE-69306)
Dna replication pre-initiation
(R-DRE-69002)
Downstream signaling events of b cell receptor (bcr)
(R-DRE-1168372)
Fbxl7 down-regulates aurka during mitotic entry and in early mitosis
(R-DRE-8854050)
G1/s dna damage checkpoints
(R-DRE-69615)
G1/s transition
(R-DRE-69206)
G2/m checkpoints
(R-DRE-69481)
G2/m transition
(R-DRE-69275)
Gene expression (transcription)
(R-DRE-74160)
Generic transcription pathway
(R-DRE-212436)
Gli3 is processed to gli3r by the proteasome
(R-DRE-5610785)
Gsk3b and btrc:cul1-mediated-degradation of nfe2l2
(R-DRE-9762114)
Hedgehog 'off' state
(R-DRE-5610787)
Hedgehog 'on' state
(R-DRE-5632684)
Hedgehog ligand biogenesis
(R-DRE-5358346)
Immune system
(R-DRE-168256)
Intracellular signaling by second messengers
(R-DRE-9006925)
Keap1-nfe2l2 pathway
(R-DRE-9755511)
Mapk6/mapk4 signaling
(R-DRE-5687128)
Mapk family signaling cascades
(R-DRE-5683057)
Metabolism
(R-DRE-1430728)
Metabolism of amino acids and derivatives
(R-DRE-71291)
Metabolism of polyamines
(R-DRE-351202)
Metabolism of proteins
(R-DRE-392499)
Metabolism of rna
(R-DRE-8953854)
Mitotic g1 phase and g1/s transition
(R-DRE-453279)
Mitotic g2-g2/m phases
(R-DRE-453274)
Neddylation
(R-DRE-8951664)
Nuclear events mediated by nfe2l2
(R-DRE-9759194)
P53-dependent g1 dna damage response
(R-DRE-69563)
P53-dependent g1/s dna damage checkpoint
(R-DRE-69580)
Pcp/ce pathway
(R-DRE-4086400)
Pip3 activates akt signaling
(R-DRE-1257604)
Post-translational protein modification
(R-DRE-597592)
Pten regulation
(R-DRE-6807070)
Regulation of mrna stability by proteins that bind au-rich elements
(R-DRE-450531)
Regulation of ornithine decarboxylase (odc)
(R-DRE-350562)
Regulation of pten stability and activity
(R-DRE-8948751)
Regulation of runx2 expression and activity
(R-DRE-8939902)
Regulation of runx3 expression and activity
(R-DRE-8941858)
Rna polymerase ii transcription
(R-DRE-73857)
Runx1 regulates transcription of genes involved in differentiation of hscs
(R-DRE-8939236)
Scf(skp2)-mediated degradation of p27/p21
(R-DRE-187577)
Signaling by hedgehog
(R-DRE-5358351)
Signaling by the b cell receptor (bcr)
(R-DRE-983705)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
S phase
(R-DRE-69242)
Stabilization of p53
(R-DRE-69541)
Switching of origins to a post-replicative state
(R-DRE-69052)
Synthesis of dna
(R-DRE-69239)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-DRE-8852276)
Transcriptional regulation by runx1
(R-DRE-8878171)
Transcriptional regulation by runx2
(R-DRE-8878166)
Transcriptional regulation by runx3
(R-DRE-8878159)
Transport of small molecules
(R-DRE-382551)
Ub-specific processing proteases
(R-DRE-5689880)
Ubiquitin-dependent degradation of cyclin d
(R-DRE-75815)
Uch proteinases
(R-DRE-5689603)
Cytoplasm
(GO:0005737)
Endopeptidase activator activity
(GO:0061133)
Nucleoplasm
(GO:0005654)
Positive regulation of endopeptidase activity
(GO:0010950)
Proteasome activator complex
(GO:0008537)
Proteasome complex
(GO:0000502)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Regulation of proteasomal protein catabolic process
(GO:0061136)

Other Information

Proteins

Q9PTH5_DANRE

Genular Protein ID: 3885334610

Symbol: Q9PTH5_DANRE

Name: N/A

UniProtKB Accession Codes:

Q9PTH5 F6NJT7 Q6DHV3

Database IDs:

Citations:

PubMed ID: 10849367

Title: Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish.

PubMed ID: 10849367

DOI: 10.1046/j.1365-3083.2000.00728.x

PubMed ID: 14597164

Title: Cloning and sequence analysis of cDNA for the proteasome activator PA28-beta subunit of flounder (Paralichthys olivaceus).

PubMed ID: 14597164

DOI: 10.1016/j.molimm.2003.08.005

PubMed ID: 16901544

Title: Molecular cloning of proteasome activator PA28-beta subunit of large yellow croaker (Pseudosciana crocea) and its coordinated up-regulation with MHC class I alpha-chain and beta 2-microglobulin in poly I:C-treated fish.

PubMed ID: 16901544

DOI: 10.1016/j.molimm.2006.06.024

PubMed ID: 18335061

Title: Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.

PubMed ID: 18335061

PubMed ID: 19084604

Title: Zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) mediates multiple intracellular signaling pathways.

PubMed ID: 19084604

PubMed ID: 22805612

Title: RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish.

PubMed ID: 22805612

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 26469318

Title: RFX transcription factors are essential for hearing in mice.

PubMed ID: 26469318

PubMed ID: 27409813

Title: Unexpected role of interferon-gamma in regulating neuronal connectivity and social behaviour.

PubMed ID: 27409813

PubMed ID: 28698226

Title: Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling.

PubMed ID: 28698226

PubMed ID: 28758957

Title: Transcriptome Analysis Reveals Increases in Visceral Lipogenesis and Storage and Activation of the Antigen Processing and Presentation Pathway during the Mouth-Opening Stage in Zebrafish Larvae.

PubMed ID: 28758957

Sequence Information:

Length: 248
Mass: 28213
Checksum: 32E3C8D9C6C4200B
Sequence:

MTSLDMSPAS KKQVDGFSQK ITKEAEQLIS KIFPEKIAEM DNVLQGSCSL KDLSVIKAPL 
DIPIPDPVKE ELKRKKKEEK EAKEGKKDKE DEDAGPPCGP IACNETVEKL IKQIKPEIQT 
LKECLNTVSM WIQLQVPRIE DGNNFGVAVQ EKVFELMTNT RTKIEGFQTQ ISKYYSERGD 
AVAKASKQPH VGDFRQLVHE LDQHQYCELR IIVLEIRNTY AMLYDVITKN FDKIKKPRGD 
LSSKALIY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: psme1

Associated with

Other Information

Identification and linkage of the proteasome activator complex PA28 subunit genes in zebrafish. PubMed ID: 10849367

Cloning and sequence analysis of cDNA for the proteasome activator PA28-beta subunit of flounder (Paralichthys olivaceus). PubMed ID: 14597164

Molecular cloning of proteasome activator PA28-beta subunit of large yellow croaker (Pseudosciana crocea) and its coordinated up-regulation with MHC class I alpha-chain and beta 2-microglobulin in poly I:C-treated fish. PubMed ID: 16901544

Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. PubMed ID: 18335061

Zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) mediates multiple intracellular signaling pathways. PubMed ID: 19084604

RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish. PubMed ID: 22805612

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

RFX transcription factors are essential for hearing in mice. PubMed ID: 26469318

Unexpected role of interferon-gamma in regulating neuronal connectivity and social behaviour. PubMed ID: 27409813

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. PubMed ID: 28698226

Transcriptome Analysis Reveals Increases in Visceral Lipogenesis and Storage and Activation of the Antigen Processing and Presentation Pathway during the Mouth-Opening Stage in Zebrafish Larvae. PubMed ID: 28758957