lef1 | ENSDARG00000031894 | NCBI 30701

Details for: lef1

Gene ID: 30701

Symbol: lef1

Ensembl ID: ENSDARG00000031894

Description: lymphoid enhancer-binding factor 1

Associated with

Deactivation of the beta-catenin transactivating complex
(R-DRE-3769402)
Degradation of beta-catenin by the destruction complex
(R-DRE-195253)
Formation of the beta-catenin:tcf transactivating complex
(R-DRE-201722)
Gene expression (transcription)
(R-DRE-74160)
Generic transcription pathway
(R-DRE-212436)
Repression of wnt target genes
(R-DRE-4641265)
Rna polymerase ii transcription
(R-DRE-73857)
Signaling by wnt
(R-DRE-195721)
Signal transduction
(R-DRE-162582)
Tcf dependent signaling in response to wnt
(R-DRE-201681)
Transcriptional regulation by ventx
(R-DRE-8853884)
Beta-catenin-tcf complex
(GO:1990907)
Canonical wnt signaling pathway
(GO:0060070)
Caudal fin development
(GO:0033336)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Dna binding, bending
(GO:0008301)
Fin development
(GO:0033333)
Fin morphogenesis
(GO:0033334)
Fin regeneration
(GO:0031101)
Forebrain neuron differentiation
(GO:0021879)
Hypothalamus cell differentiation
(GO:0021979)
Hypothalamus development
(GO:0021854)
Muscle cell development
(GO:0055001)
Neural crest cell migration
(GO:0001755)
Neurogenesis
(GO:0022008)
Nucleus
(GO:0005634)
Pectoral fin development
(GO:0033339)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neurogenesis
(GO:0050769)
Posterior lateral line development
(GO:0048916)
Posterior lateral line neuromast deposition
(GO:0048922)
Posterior lateral line neuromast development
(GO:0048919)
Regulation of cell proliferation involved in tissue homeostasis
(GO:0060784)
Regulation of retinoic acid biosynthetic process
(GO:1900052)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Somitogenesis
(GO:0001756)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Q9W7C0_DANRE

Genular Protein ID: 1745232898

Symbol: Q9W7C0_DANRE

Name: N/A

UniProtKB Accession Codes:

Q9W7C0 B3DFM5

Database IDs:

Citations:

PubMed ID: 10446273

Title: Maternal and embryonic expression of zebrafish lef1.

PubMed ID: 10446273

DOI: 10.1016/S0925-4773(99)00101-X

PubMed ID: 14579381

Title: Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression.

PubMed ID: 14579381

PubMed ID: 15325340

Title: Sequence, linkage mapping and early developmental expression of the intestinal-type fatty acid-binding protein gene (fabp2) from zebrafish (Danio rerio).

PubMed ID: 15325340

PubMed ID: 15151990

Title: nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development.

PubMed ID: 15151990

DOI: 10.1242/dev.01171

PubMed ID: 12949138

Title: Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish.

PubMed ID: 12949138

DOI: 10.1093/molbev/msg224

PubMed ID: 15520368

Title: Hematopoietic gene expression profile in zebrafish kidney marrow.

PubMed ID: 15520368

DOI: 10.1073/pnas.0407241101

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 30451830

Title: Wnt/beta-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.

PubMed ID: 30451830

PubMed ID: 30759383

Title: Germline Stem Cells Drive Ovary Regeneration in Zebrafish.

PubMed ID: 30759383

PubMed ID: 30777146

Title: Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification.

PubMed ID: 30777146

PubMed ID: 30695061

Title: Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.

PubMed ID: 30695061

PubMed ID: 30390549

Title: Effects of 17alphaethinylestradiol on caudal fin regeneration in zebrafish larvae.

PubMed ID: 30390549

Sequence Information:

Length: 365
Mass: 41059
Checksum: 9FC39E11FDF51350
Sequence:

MPQLSGGGGG GDPELCATDE MIPFKDEGDP HKEQIFAEIS HSEEEGDLAE IKSSLVNETE 
ISPNSNSHDA ARQSQITPDS YHEKHRDHPD DGKLQDLYSK GHPYPSYPGY IMMTNMNNEP 
YMNNGSLSPP IPRTSNKVPV VQPSHAVHPL TPLITYSDEH FAPGPHSGHH PQDVNPKQAG 
MPRHHPGPDI PNFYPLSPGG VGQMTPPLGW FSHHMVPGPP GPHATGIPHP AIVNPQVKQE 
HDTDLMHMKP QHEQRKEQEP KRPHIKKPLN AFMLYMKEMR ANVVAECTLK ESAAINQILG 
RRWHALSREE QAKYYELARK ERQLHMQLYP GWSARDNYGK KKKRKREKIQ EPASGTGQRM 
KTAYI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: lef1

Associated with

Other Information

Maternal and embryonic expression of zebrafish lef1. PubMed ID: 10446273

Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression. PubMed ID: 14579381

Sequence, linkage mapping and early developmental expression of the intestinal-type fatty acid-binding protein gene (fabp2) from zebrafish (Danio rerio). PubMed ID: 15325340

nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development. PubMed ID: 15151990

Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish. PubMed ID: 12949138

Hematopoietic gene expression profile in zebrafish kidney marrow. PubMed ID: 15520368

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

Wnt/beta-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling. PubMed ID: 30451830

Germline Stem Cells Drive Ovary Regeneration in Zebrafish. PubMed ID: 30759383

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. PubMed ID: 30777146

Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation. PubMed ID: 30695061

Effects of 17alphaethinylestradiol on caudal fin regeneration in zebrafish larvae. PubMed ID: 30390549