Details for: mhc2dab

Gene ID: 30762

Symbol: mhc2dab

Ensembl ID: ENSDARG00000079105

Description: major histocompatibility complex class II DAB gene

Associated with

  • Antigen processing and presentation of exogenous peptide antigen via mhc class ii
    (GO:0019886)
  • Late endosome membrane
    (GO:0031902)
  • Lysosomal membrane
    (GO:0005765)
  • Mhc class ii protein complex
    (GO:0042613)
  • Mhc class ii protein complex binding
    (GO:0023026)
  • Molecular_function
    (GO:0003674)
  • Peptide antigen assembly with mhc class ii protein complex
    (GO:0002503)
  • Peptide antigen binding
    (GO:0042605)
  • Positive regulation of immune response
    (GO:0050778)
  • Positive regulation of t cell activation
    (GO:0050870)

Other Information

Genular Protein ID: 3765246411

Symbol: Q1MTC8_DANRE

Name: N/A

UniProtKB Accession Codes:

Q1MTC8

Database IDs:

ARBA 1 Bgee 1 CTD 1 EMBL 3 Ensembl 2 GO 10 Gene3D 1 HOGENOM 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PaxDb 1 Pfam 2 Reactome 1 RefSeq 1 SAM 2 SMART 2 STRING 1 SUPFAM 2 TreeFam 1 ZFIN 2 eggNOG 1

Citations:

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

Sequence Information:

  • Length: 250
  • Mass: 28442
  • Checksum: CBD23B23C7FCF3D8
  • Sequence:
    • MYLLKPFLVI LMLSTFTGTA DGYYDYIKQQ CFYSTSDYSD MVYLASYSFN KVVDTQFNSS 
VGKFVGYTEQ GLIFAENFNK DQAYLHQLKA QVDTFCRHNA QIWDSAVRDK AVLPEVTIKS 
VRQAEGRHPA VLLCSAYEFY PKKIKMSWLR DGKEVTSDVT STMEMADGDW YYQIHSHLEY 
TPKSGEKIQC LVEHASLTQP LTKDWNPHIS ESDRNKFAIG ASGLVLGIII AIAGLIYYKK 
KSTGRILVPN

Genular Protein ID: 2022756644

Symbol: Q8MGW8_DANRE

Name: N/A

UniProtKB Accession Codes:

Q8MGW8

Database IDs:

ARBA 1 CTD 1 EMBL 2 GO 3 Gene3D 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 2 Proteomes 2 RefSeq 2 SAM 2 SMART 2 SUPFAM 2 ZFIN 2

Citations:

PubMed ID: 8613141

Title: Trans-species polymorphism of class II Mhc loci in danio fishes.

PubMed ID: 8613141

PubMed ID: 12242592

Title: Evidence that the separation of Mhc class II from class I loci in the zebrafish, Danio rerio, occurred by translocation.

PubMed ID: 12242592

DOI: 10.1007/s00251-002-0473-5

PubMed ID: 20713961

Title: Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants.

PubMed ID: 20713961

PubMed ID: 21406720

Title: Characterization of the mononuclear phagocyte system in zebrafish.

PubMed ID: 21406720

PubMed ID: 22364494

Title: Dynamic changes in the gene expression of zebrafish Reelin receptors during embryogenesis and hatching period.

PubMed ID: 22364494

DOI: 10.1111/j.1440-169X.2012.01327.x

PubMed ID: 24279922

Title: Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.

PubMed ID: 24279922

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 27189481

Title: Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.

PubMed ID: 27189481

PubMed ID: 27765700

Title: Design and evaluation of an Edwardsiella tarda DNA vaccine co-encoding antigenic and adjuvant peptide.

PubMed ID: 27765700

PubMed ID: 27123951

Title: Ex vivo tools for the clonal analysis of zebrafish hematopoiesis.

PubMed ID: 27123951

PubMed ID: 27876605

Title: Role of zebrafish NLRC5 in antiviral response and transcriptional regulation of MHC related genes.

PubMed ID: 27876605

Sequence Information:

  • Length: 250
  • Mass: 28471
  • Checksum: 9BE13B20F7CEAE79
  • Sequence:
    • MYLLKPFLVI LMLSTFTGTA DGYYDYIKQQ CFYSTSDYSD MVYLASYSFN KVVDTQFNSS 
VGKFVGYTEQ GLIFAENFNK DQAYLHQLKA QVDTFCRHNA RIWDSAVRDK AVLPEVTIKS 
VRQAEGRHPA VLLCSAYEFY PKKIKMSWLR DGKEVTSDVT STMEMADGDW YYQIHSHLEY 
TPKSGEKIQC LVEHASLTQP LTKDWNPHIS ESDRNKFAIG ASGLVLGIII AIAGLIYYKK 
KSTGRILVPN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.