Details for: tal1

Gene ID: 30766

Symbol: tal1

Ensembl ID: ENSDARG00000019930

Description: T-cell acute lymphocytic leukemia 1

Associated with

Other Information

Genular Protein ID: 1907680569

Symbol: TAL1_DANRE

Name: T-cell acute lymphocytic leukemia protein 1 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9670018

Title: The SCL gene specifies haemangioblast development from early mesoderm.

PubMed ID: 9670018

DOI: 10.1093/emboj/17.14.4029

PubMed ID: 9499398

Title: SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish.

PubMed ID: 9499398

DOI: 10.1101/gad.12.5.621

PubMed ID: 17472439

Title: Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis.

PubMed ID: 17472439

DOI: 10.1371/journal.pbio.0050132

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 10208748

Title: Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor binding sites.

PubMed ID: 10208748

DOI: 10.1006/dbio.1999.9236

PubMed ID: 11003831

Title: Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish.

PubMed ID: 11003831

DOI: 10.1242/dev.127.20.4303

PubMed ID: 11381108

Title: Regulation of the stem cell leukemia (SCL) gene: a tale of two fishes.

PubMed ID: 11381108

DOI: 10.1073/pnas.101532998

PubMed ID: 14602685

Title: Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

PubMed ID: 14602685

DOI: 10.1242/dev.00875

PubMed ID: 15644413

Title: Scl is required for dorsal aorta as well as blood formation in zebrafish embryos.

PubMed ID: 15644413

DOI: 10.1182/blood-2004-09-3547

PubMed ID: 15617691

Title: Zebrafish scl functions independently in hematopoietic and endothelial development.

PubMed ID: 15617691

DOI: 10.1016/j.ydbio.2004.09.004

PubMed ID: 16210319

Title: Distinct roles for SCL in erythroid specification and maturation in zebrafish.

PubMed ID: 16210319

DOI: 10.1074/jbc.m507998200

PubMed ID: 17090656

Title: The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish.

PubMed ID: 17090656

DOI: 10.1182/blood-2006-02-003087

PubMed ID: 17722983

Title: Early endocardial morphogenesis requires Scl/Tal1.

PubMed ID: 17722983

DOI: 10.1371/journal.pgen.0030140

Sequence Information:

  • Length: 324
  • Mass: 35705
  • Checksum: 28B98591156C40F6
  • Sequence:
  • MMEKLKSEQF PLSPSAEGCA SPPRGDGDAR GKQEGTTAET GEHRLPEELN GVAKETAHHA 
    TELKKEVAVI ELSRRGGSAD IKGRELKAEL SHKVQTTELC RPPIPLPLPP RDPLSDTRMV 
    QLSPPAFPLP ARAMLYSNMT TPLATINSGF AGDAEQYGMY PSNRVKRRPA PYEVEINDGS 
    QPKIVRRIFT NSRERWRQQN VNGAFAELRK LIPTHPPDKK LSKNEILRLA MKYINFLAKL 
    LNDQDDMVGG EAPARANRDS RDATLVRDDL LQEMLSPNSS CGSLLDGDAS PESFTEDQDS 
    SVESRPSARG LHHSSLPLDG NAQR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.