Apln | ENSMUSG00000037010 | NCBI 30878

Details for: Apln

Gene ID: 30878

Symbol: Apln

Ensembl ID: ENSMUSG00000037010

Description: apelin

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Angiogenesis
(GO:0001525)
Apelin receptor binding
(GO:0031704)
Apelin receptor signaling pathway
(GO:0060183)
Coronary vasculature development
(GO:0060976)
Drinking behavior
(GO:0042756)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Feeding behavior
(GO:0007631)
Gastrulation
(GO:0007369)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Multicellular organism development
(GO:0007275)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of systemic arterial blood pressure
(GO:0003085)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Negative regulation of vasoconstriction
(GO:0045906)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of corticotropin-releasing hormone secretion
(GO:0051466)
Positive regulation of corticotropin secretion
(GO:0051461)
Positive regulation of g protein-coupled receptor internalization
(GO:1904022)
Positive regulation of heart contraction
(GO:0045823)
Positive regulation of heart rate
(GO:0010460)
Positive regulation of heat generation
(GO:0031652)
Positive regulation of mirna transcription
(GO:1902895)
Positive regulation of phosphorylation
(GO:0042327)
Positive regulation of vascular endothelial cell proliferation
(GO:1905564)
Regulation of body fluid levels
(GO:0050878)
Regulation of the force of heart contraction
(GO:0002026)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)

Other Information

Proteins

Apelin

Genular Protein ID: 187335956

Symbol: APEL_MOUSE

Name: Apelin

UniProtKB Accession Codes:

Q9R0R4

Database IDs:

Citations:

PubMed ID: 10525157

Title: Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum.

PubMed ID: 10525157

DOI: 10.1016/s0167-4889(99)00114-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11359874

Title: Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.

PubMed ID: 11359874

DOI: 10.1046/j.1471-4159.2001.00320.x

PubMed ID: 26611206

Title: Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart.

PubMed ID: 26611206

DOI: 10.1007/s00395-015-0521-6

PubMed ID: 28854362

Title: Loss of Apela peptide in mice causes low penetrance embryonic lethality and defects in early mesodermal derivatives.

PubMed ID: 28854362

DOI: 10.1016/j.celrep.2017.08.014

PubMed ID: 28890073

Title: Alternative progenitor cells compensate to rebuild the coronary vasculature in Elabela- and Apj-deficient hearts.

PubMed ID: 28890073

DOI: 10.1016/j.devcel.2017.08.008

Sequence Information:

Length: 77
Mass: 8658
Checksum: D71E0D58E47D2376
Sequence:

MNLRLCVQAL LLLWLSLTAV CGVPLMLPPD GTGLEEGSMR YLVKPRTSRT GPGAWQGGRR 
KFRRQRPRLS HKGPMPF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apln

Associated with

Other Information

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum. PubMed ID: 10525157

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain. PubMed ID: 11359874

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart. PubMed ID: 26611206

Loss of Apela peptide in mice causes low penetrance embryonic lethality and defects in early mesodermal derivatives. PubMed ID: 28854362