Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 270.0179
Cell Significance Index: -42.0000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 132.4695
Cell Significance Index: -33.6000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 107.4935
Cell Significance Index: -43.6700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 94.9965
Cell Significance Index: -44.8500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 94.5984
Cell Significance Index: -48.6600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 46.6827
Cell Significance Index: -44.5700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 33.9023
Cell Significance Index: -41.8000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.7069
Cell Significance Index: -42.2500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.5227
Cell Significance Index: -25.5100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 9.3050
Cell Significance Index: -28.5800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 6.1455
Cell Significance Index: -13.4500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 5.6791
Cell Significance Index: 72.7300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 4.4244
Cell Significance Index: 116.3400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 4.1706
Cell Significance Index: 45.3400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 3.9389
Cell Significance Index: 115.6800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 3.3748
Cell Significance Index: 70.6400 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 2.8278
Cell Significance Index: 17.5000 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.4990
Cell Significance Index: 13.1500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.9269
Cell Significance Index: 22.9700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4528
Cell Significance Index: 291.4400 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: 1.3807
Cell Significance Index: 23.7200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2375
Cell Significance Index: 56.0900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.1412
Cell Significance Index: 156.7200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9685
Cell Significance Index: 124.1600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.9419
Cell Significance Index: 60.7700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.8696
Cell Significance Index: 23.2600 - Cell Name: theca cell (CL0000503)
Fold Change: 0.8323
Cell Significance Index: 4.8900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.7200
Cell Significance Index: 53.6600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.7121
Cell Significance Index: 44.8800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.6712
Cell Significance Index: 79.1600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6157
Cell Significance Index: 60.9100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5871
Cell Significance Index: 406.0400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5462
Cell Significance Index: 195.9200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5286
Cell Significance Index: 104.9100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.3556
Cell Significance Index: 15.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.3369
Cell Significance Index: 25.8600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3310
Cell Significance Index: 17.3800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3204
Cell Significance Index: 19.7000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3003
Cell Significance Index: 48.8400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2849
Cell Significance Index: 10.7900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.2726
Cell Significance Index: 5.3200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2514
Cell Significance Index: 11.8200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1968
Cell Significance Index: 10.2500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1202
Cell Significance Index: 20.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1097
Cell Significance Index: 14.1800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1007
Cell Significance Index: 189.6400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0804
Cell Significance Index: 8.7500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0767
Cell Significance Index: 14.5900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0714
Cell Significance Index: 2.5100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0648
Cell Significance Index: 1.0900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0362
Cell Significance Index: 22.9800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0324
Cell Significance Index: 14.6900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0285
Cell Significance Index: 0.7600 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.0119
Cell Significance Index: 0.0600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0010
Cell Significance Index: 0.4600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0030
Cell Significance Index: -5.5200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0049
Cell Significance Index: -0.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0098
Cell Significance Index: -6.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0125
Cell Significance Index: -0.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0159
Cell Significance Index: -24.5100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0174
Cell Significance Index: -12.9100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0338
Cell Significance Index: -46.0200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0353
Cell Significance Index: -26.6900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0354
Cell Significance Index: -1.0100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0391
Cell Significance Index: -28.6400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0410
Cell Significance Index: -22.3900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0564
Cell Significance Index: -3.7900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0567
Cell Significance Index: -31.9600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0953
Cell Significance Index: -20.0700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1088
Cell Significance Index: -12.6800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1210
Cell Significance Index: -3.1100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1252
Cell Significance Index: -12.7900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1335
Cell Significance Index: -38.4100 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.1357
Cell Significance Index: -1.1400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1595
Cell Significance Index: -23.1900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1907
Cell Significance Index: -8.8900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1988
Cell Significance Index: -13.7500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.2026
Cell Significance Index: -36.5200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2553
Cell Significance Index: -29.1500 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2681
Cell Significance Index: -6.8500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2844
Cell Significance Index: -29.6100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3286
Cell Significance Index: -37.6500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.3325
Cell Significance Index: -40.8900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3453
Cell Significance Index: -11.0600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3485
Cell Significance Index: -20.9200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3623
Cell Significance Index: -25.6200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.4398
Cell Significance Index: -11.0000 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.4587
Cell Significance Index: -5.7200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.4868
Cell Significance Index: -11.6800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4877
Cell Significance Index: -7.2000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.5048
Cell Significance Index: -9.3300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5235
Cell Significance Index: -10.8600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5400
Cell Significance Index: -15.0900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5574
Cell Significance Index: -44.1500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5621
Cell Significance Index: -11.9300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5854
Cell Significance Index: -35.8900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5964
Cell Significance Index: -10.2200 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.6177
Cell Significance Index: -10.4100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6415
Cell Significance Index: -18.3900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6455
Cell Significance Index: -36.2200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2115721325
Symbol: ANXA6_HUMAN
Name: Annexin A6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3258820
Title: Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family.
PubMed ID: 3258820
PubMed ID: 2963335
Title: Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.
PubMed ID: 2963335
PubMed ID: 2528541
Title: Structure and expression of cDNA for calphobindin II, a human placental coagulation inhibitor.
PubMed ID: 2528541
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2139657
Title: Structure and properties of calphobindin II, an anticoagulant protein from human placenta.
PubMed ID: 2139657
PubMed ID: 15242332
Title: Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.
PubMed ID: 15242332
DOI: 10.1042/bj20040647
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 8709144
Title: The structure of recombinant human annexin VI in crystals and membrane-bound.
PubMed ID: 8709144
Sequence Information:
- Length: 673
- Mass: 75873
- Checksum: 90F47474F7F6D7B6
- Sequence:
MAKPAQGAKY RGSIHDFPGF DPNQDAEALY TAMKGFGSDK EAILDIITSR SNRQRQEVCQ SYKSLYGKDL IADLKYELTG KFERLIVGLM RPPAYCDAKE IKDAISGIGT DEKCLIEILA SRTNEQMHQL VAAYKDAYER DLEADIIGDT SGHFQKMLVV LLQGTREEDD VVSEDLVQQD VQDLYEAGEL KWGTDEAQFI YILGNRSKQH LRLVFDEYLK TTGKPIEASI RGELSGDFEK LMLAVVKCIR STPEYFAERL FKAMKGLGTR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAY QMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLG TDEDTIIDII THRSNVQRQQ IRQTFKSHFG RDLMTDLKSE ISGDLARLIL GLMMPPAHYD AKQLKKAMEG AGTDEKALIE ILATRTNAEI RAINEAYKED YHKSLEDALS SDTSGHFRRI LISLATGHRE EGGENLDQAR EDAQVAAEIL EIADTPSGDK TSLETRFMTI LCTRSYPHLR RVFQEFIKMT NYDVEHTIKK EMSGDVRDAF VAIVQSVKNK PLFFADKLYK SMKGAGTDEK TLTRIMVSRS EIDLLNIRRE FIEKYDKSLH QAIEGDTSGD FLKALLALCG GED
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.