Foxe3 | ENSMUSG00000044518 | NCBI 30923

Details for: Foxe3

Gene ID: 30923

Symbol: Foxe3

Ensembl ID: ENSMUSG00000044518

Description: forkhead box E3

Associated with

Anatomical structure morphogenesis
(GO:0009653)
Camera-type eye development
(GO:0043010)
Cell development
(GO:0048468)
Cell differentiation
(GO:0030154)
Ciliary body morphogenesis
(GO:0061073)
Cornea development in camera-type eye
(GO:0061303)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Epithelial cell proliferation
(GO:0050673)
Eye development
(GO:0001654)
Iris morphogenesis
(GO:0061072)
Lens development in camera-type eye
(GO:0002088)
Mrna transcription by rna polymerase ii
(GO:0042789)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of lens fiber cell differentiation
(GO:1902747)
Nucleus
(GO:0005634)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of lens epithelial cell proliferation
(GO:2001111)
Regulation of cell cycle
(GO:0051726)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Trabecular meshwork development
(GO:0002930)
Transcription by rna polymerase ii
(GO:0006366)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Forkhead box protein E3

Genular Protein ID: 2861056218

Symbol: FOXE3_MOUSE

Name: Forkhead box protein E3

UniProtKB Accession Codes:

Q9QY14

Database IDs:

Citations:

PubMed ID: 10652278

Title: A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle.

PubMed ID: 10652278

PubMed ID: 10890982

Title: Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation.

PubMed ID: 10890982

DOI: 10.1002/1526-968x(200006)27:2<81::aid-gene50>3.0.co;2-n

PubMed ID: 11980846

Title: Foxe3 haploinsufficiency in mice: a model for Peters' anomaly.

PubMed ID: 11980846

PubMed ID: 16199865

Title: Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice.

PubMed ID: 16199865

DOI: 10.1128/mcb.25.20.8854-8863.2005

PubMed ID: 17064680

Title: Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.

PubMed ID: 17064680

DOI: 10.1016/j.ydbio.2006.09.021

PubMed ID: 26854927

Title: FOXE3 mutations predispose to thoracic aortic aneurysms and dissections.

PubMed ID: 26854927

DOI: 10.1172/jci83778

PubMed ID: 27218149

Title: FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1.

PubMed ID: 27218149

DOI: 10.1038/ncomms10953

Sequence Information:

Length: 288
Mass: 30541
Checksum: 16425926F3E466C5
Sequence:

MDAQVAFSGF PALPSLTPSG PQLPTLAGAE PGREPEEVVG GGDAEPTAVP GPGKRRRRPL 
QRGKPPYSYI ALIAMALAHA PGRRLTLAAI YRFITERFAF YRDSPRKWQN SIRHNLTLND 
CFVKVPREPG NPGKGNYWTL DPAAADMFDN GSFLRRRKRF KRAELPAPPP PPPPFPYAPF 
PPPPAPASAP PARLFRLDSL LGLQPEPPGP VAPEPPCCAA PDAAFPPCAA AASPPLYSPA 
SERLGLPAPL PAQPLLALAG SAGALGPLGA GEAYLRQPGF APGLERYL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Foxe3

Associated with

Other Information

A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. PubMed ID: 10652278

Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. PubMed ID: 10890982

Foxe3 haploinsufficiency in mice: a model for Peters' anomaly. PubMed ID: 11980846

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. PubMed ID: 16199865

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. PubMed ID: 17064680

FOXE3 mutations predispose to thoracic aortic aneurysms and dissections. PubMed ID: 26854927

FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1. PubMed ID: 27218149