Details for: Slc46a2

Gene ID: 30936

Symbol: Slc46a2

Ensembl ID: ENSMUSG00000028386

Description: solute carrier family 46, member 2

Associated with

Other Information

Genular Protein ID: 3468207610

Symbol: S46A2_MOUSE

Name: Solute carrier family 46 member 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10706709

Title: A putative 12 transmembrane domain cotransporter expressed in thymic cortical epithelial cells.

PubMed ID: 10706709

DOI: 10.4049/jimmunol.164.6.3185

PubMed ID: 10978518

Title: Characterization of the mouse gene, human promoter and human cDNA of TSCOT reveals strong interspecies homology.

PubMed ID: 10978518

DOI: 10.1016/s0167-4781(00)00177-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 28539433

Title: SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans.

PubMed ID: 28539433

DOI: 10.4049/jimmunol.1600409

PubMed ID: 34235268

Title: Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes.

PubMed ID: 34235268

DOI: 10.1021/acscentsci.1c00440

PubMed ID: 37116499

Title: Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.

PubMed ID: 37116499

DOI: 10.1016/j.immuni.2023.04.001

Sequence Information:

  • Length: 479
  • Mass: 52083
  • Checksum: EC8BEF1E446A5CFB
  • Sequence:
  • MGPGGTCPWS SRLSGFRVRT WIEPVVASTQ VAGSLYDAGL LLVVKESFKS EAGGSSNYSA 
    NQSLVEYQED QQQKAISNFN IIYNLVLGLT PLLSAYGLGW LSDRYHRKIS ICTAMLGFLL 
    SRIGLLLKVM LDWPVEVMYG AAALNGLCGS FSAYWSGVMA LGSLGCSEGR RSVRLILIDL 
    VLGLAGFSGS MASGHLFKQI VGHSAQGLLL TACSVGCAAF ALFYSLFVLK VPESKPNKVH 
    PTVDTVSGMM GTYRTLDPDQ QDKQNVPRNP RTPGKGKSSQ REVVALLFVG AIIYDLAAVG 
    TVDVMALFVL KEPLHWNQVQ LGYGMASGYI IFITSFLGVL VFSRCFRDTT MIIIGMLSFG 
    SGALLLAFVK ETYMFYIARA IMLFALIPIT TIRSAMSKLI KDSSYGKIFV ILQLCLTLTG 
    VVTSTIYNKI YQLTLDKFIG TCFVLSSFLS FLAIVPIGVV AYKQVPRSQQ GECAEKQRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.