Siva1 | ENSMUSG00000064326 | NCBI 30954

Details for: Siva1

Gene ID: 30954

Symbol: Siva1

Ensembl ID: ENSMUSG00000064326

Description: SIVA1, apoptosis-inducing factor

Associated with

Activation-induced cell death of t cells
(GO:0006924)
Apoptotic process
(GO:0006915)
Cd27 receptor binding
(GO:0005175)
Cytoplasm
(GO:0005737)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Negative regulation of nf-kappab transcription factor activity
(GO:0032088)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901030)
Tumor necrosis factor receptor binding
(GO:0005164)
Virus receptor activity
(GO:0001618)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Apoptosis regulatory protein Siva

Genular Protein ID: 1438728956

Symbol: SIVA_MOUSE

Name: Apoptosis regulatory protein Siva

UniProtKB Accession Codes:

O54926 Q3U6J2 Q921I8 Q9CWL1 Q9R1Q0 Q9R1Q1

Database IDs:

Citations:

PubMed ID: 10597319

Title: Murine Siva-1 and Siva-2, alternate splice forms of the mouse Siva gene, both bind to CD27 but differentially transduce apoptosis.

PubMed ID: 10597319

DOI: 10.1038/sj.onc.1203144

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9177220

Title: CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.

PubMed ID: 9177220

DOI: 10.1073/pnas.94.12.6346

PubMed ID: 10756043

Title: Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva.

PubMed ID: 10756043

DOI: 10.1128/jvi.74.9.4284-4290.2000

PubMed ID: 12478477

Title: GITR interacts with the pro-apoptotic protein Siva and induces apoptosis.

PubMed ID: 12478477

DOI: 10.1038/sj.cdd.4401140

PubMed ID: 15105421

Title: The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1.

PubMed ID: 15105421

DOI: 10.1074/jbc.m400376200

Sequence Information:

Length: 175
Mass: 18770
Checksum: 1E132C1580ABE3F2
Sequence:

MPKRSCPFAD AAPLQLKVHV GLKELSHGVF AERYSREVFE RTKQLLFQGA RAYRDHISSE 
DCSVNHLQES LKSGVVGAPQ PARGQMLIGP DGRLTRCQAQ ASEGGLPRTA PIACSSCMRS 
VDGKAVCSQC ERALCGQCVY TCWGCGALAC VLCGLADYAD DGEKTLCTSC AMFEA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Siva1

Associated with

Other Information

Murine Siva-1 and Siva-2, alternate splice forms of the mouse Siva gene, both bind to CD27 but differentially transduce apoptosis. PubMed ID: 10597319

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. PubMed ID: 9177220

Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva. PubMed ID: 10756043

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis. PubMed ID: 12478477

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. PubMed ID: 15105421