Details for: sc

Gene ID: 30982

Symbol: sc

Ensembl ID: FBgn0004170

Description: scute

Associated with

  • Central nervous system development
    (GO:0007417)
  • Chaeta development
    (GO:0022416)
  • Chaeta morphogenesis
    (GO:0008407)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Enteroendocrine cell differentiation
    (GO:0035883)
  • Malpighian tubule tip cell differentiation
    (GO:0061382)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Nervous system development
    (GO:0007399)
  • Neuroblast fate determination
    (GO:0007400)
  • Peripheral nervous system development
    (GO:0007422)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein dimerization activity
    (GO:0046983)
  • Protein heterodimerization activity
    (GO:0046982)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of mitotic cell cycle
    (GO:0007346)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sensory organ development
    (GO:0007423)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sex determination
    (GO:0007530)
  • Sex determination, establishment of x:a ratio
    (GO:0007540)
  • Transcription regulator complex
    (GO:0005667)
  • Ventral cord development
    (GO:0007419)

Other Information

Genular Protein ID: 973551740

Symbol: AST4_DROME

Name: Achaete-scute complex protein T4

UniProtKB Accession Codes:

P10084 O76890 Q4V705

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 FlyBase 1 GO 25 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 3111716

Title: The achaete-scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc.

PubMed ID: 3111716

DOI: 10.1016/0092-8674(87)90495-8

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731137

Title: From sequence to chromosome: the tip of the X chromosome of D. melanogaster.

PubMed ID: 10731137

DOI: 10.1126/science.287.5461.2220

PubMed ID: 2583094

Title: The scute (T4) gene acts as a numerator element of the X: a signal that determines the state of activity of sex-lethal in Drosophila.

PubMed ID: 2583094

DOI: 10.1002/j.1460-2075.1989.tb08459.x

PubMed ID: 8370520

Title: A bZIP protein, sisterless-a, collaborates with bHLH transcription factors early in Drosophila development to determine sex.

PubMed ID: 8370520

DOI: 10.1101/gad.7.9.1688

PubMed ID: 7651341

Title: Protein-protein interactions among components of the Drosophila primary sex determination signal.

PubMed ID: 7651341

DOI: 10.1007/bf02190799

PubMed ID: 16083904

Title: Drosophila BAP60 is an essential component of the Brahma complex, required for gene activation and repression.

PubMed ID: 16083904

DOI: 10.1016/j.jmb.2005.07.009

Sequence Information:

  • Length: 345
  • Mass: 38155
  • Checksum: DE68E49A8CCF16EB
  • Sequence:
    • MKNNNNTTKS TTMSSSVLST NETFPTTINS ATKIFRYQHI MPAPSPLIPG GNQNQPAGTM 
PIKTRKYTPR GMALTRCSES VSSLSPGSSP APYNVDQSQS VQRRNARERN RVKQVNNSFA 
RLRQHIPQSI ITDLTKGGGR GPHKKISKVD TLRIAVEYIR RLQDLVDDLN GGSNIGANNA 
VTQLQLCLDE SSSHSSSSST CSSSGHNTYY QNTISVSPLQ QQQQLQRQQF NHQPLTALSL 
NTNLVGTSVP GGDAGCVSTS KNQQTCHSPT SSFNSSMSFD SGTYEGVPQQ ISTHLDRLDH 
LDNELHTHSQ LQLKFEPYEH FQLDEEDCTP DDEEILDYIS LWQEQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.