Details for: ACACA

Gene ID: 31

Symbol: ACACA

Ensembl ID: ENSG00000278540

Description: acetyl-CoA carboxylase alpha

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 5.81
    Marker Score: 2822
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 4.95
    Marker Score: 10246
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 4.88
    Marker Score: 64895
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 3.35
    Marker Score: 1225
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.09
    Marker Score: 7726
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.93
    Marker Score: 3322
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.79
    Marker Score: 2472.5
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 2.77
    Marker Score: 7834
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.59
    Marker Score: 2860
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.57
    Marker Score: 1504
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.57
    Marker Score: 19711
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.56
    Marker Score: 97086.5
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.55
    Marker Score: 11815
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.55
    Marker Score: 1773
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.55
    Marker Score: 50701
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.5
    Marker Score: 37329
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.47
    Marker Score: 52762
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.46
    Marker Score: 4724
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.39
    Marker Score: 9897
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.39
    Marker Score: 2531
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.33
    Marker Score: 2821
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.33
    Marker Score: 3129
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.31
    Marker Score: 966
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.3
    Marker Score: 84717
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.17
    Marker Score: 2338.5
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.16
    Marker Score: 6150
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.14
    Marker Score: 5407
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.14
    Marker Score: 20101
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.13
    Marker Score: 1243
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.12
    Marker Score: 8205
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 2.12
    Marker Score: 671
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.1
    Marker Score: 4613.5
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.06
    Marker Score: 1195
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.03
    Marker Score: 124800.5
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.03
    Marker Score: 3364
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2
    Marker Score: 8358
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.99
    Marker Score: 582
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.98
    Marker Score: 3452
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.91
    Marker Score: 3212
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.89
    Marker Score: 17963
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.88
    Marker Score: 724
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.87
    Marker Score: 592
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.84
    Marker Score: 15823
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.78
    Marker Score: 485.5
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.75
    Marker Score: 981
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.74
    Marker Score: 973
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.72
    Marker Score: 1985
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.69
    Marker Score: 1300
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.69
    Marker Score: 2386
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.61
    Marker Score: 5738
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.61
    Marker Score: 2485
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.55
    Marker Score: 817
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.54
    Marker Score: 34430
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.52
    Marker Score: 437
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.51
    Marker Score: 3603
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.5
    Marker Score: 1871
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.5
    Marker Score: 3531
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.5
    Marker Score: 894
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.49
    Marker Score: 979.5
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.48
    Marker Score: 169657
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.45
    Marker Score: 9440.5
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.43
    Marker Score: 452
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.34
    Marker Score: 8587.5
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.32
    Marker Score: 871
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.25
    Marker Score: 403
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.25
    Marker Score: 5379.5
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.22
    Marker Score: 6550
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.22
    Marker Score: 814
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.21
    Marker Score: 457
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.19
    Marker Score: 1280.5
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.17
    Marker Score: 4771
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.16
    Marker Score: 294.5
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.15
    Marker Score: 464
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.14
    Marker Score: 397
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.1
    Marker Score: 1178
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 1.1
    Marker Score: 290.5
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.09
    Marker Score: 340
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.08
    Marker Score: 392
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.08
    Marker Score: 281
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.08
    Marker Score: 586
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.06
    Marker Score: 1120
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.06
    Marker Score: 214.5
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 1.05
    Marker Score: 466
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.04
    Marker Score: 6924
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.04
    Marker Score: 512
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.03
    Marker Score: 270
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.03
    Marker Score: 379
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.01
    Marker Score: 879
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.01
    Marker Score: 2705
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1
    Marker Score: 585
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1
    Marker Score: 1442
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1
    Marker Score: 341
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.99
    Marker Score: 478
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.99
    Marker Score: 1596
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.99
    Marker Score: 946
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.99
    Marker Score: 492
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.96
    Marker Score: 769
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.96
    Marker Score: 385
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 488.5

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Other Information

**Key characteristics:** - ACACA is a key enzyme in the citric acid cycle, which is responsible for the production of energy for cells. - It is a multi-functional enzyme that can act as a carboxylase or a transferase. - It is involved in the metabolism of various substrates, including acetyl-CoA, oxaloacetate, and malate. - It is a regulator of cholesterol biosynthesis and plays a role in maintaining blood cholesterol levels. **Pathways and functions:** - Acetyl-CoA carboxylase activity is involved in the synthesis of carnitine, a molecule that acts as an energy storage molecule in muscle and fat cells. - It is also involved in the metabolism of fatty acids, including the synthesis of ketone bodies. - ACACA also plays a role in the regulation of cholesterol biosynthesis and blood cholesterol levels. **Clinical significance:** - Defects in ACACA can lead to a condition called defective acetyl-CoA carboxylase deficiency, which is associated with an increased risk of cardiovascular disease, stroke, and peripheral artery disease. - The gene is also associated with other metabolic disorders, such as fatty acid oxidation disorders and mitochondrial disorders. - Mutations in ACACA have been linked to the development of some types of cancer.

Genular Protein ID: 2995344937

Symbol: ACACA_HUMAN

Name: Acetyl-Coenzyme A carboxylase alpha

UniProtKB Accession Codes:

Q13085 B2RP68 B2ZZ90 Q6KEV6 Q6XDA8 Q7Z2G8 Q7Z561 Q7Z563 Q7Z564 Q86WB2 Q86WB3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CPTAC 1 CTD 1 ChEBI 22 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 ELM 1 EMBL 16 EMDB 3 EPD 1 Ensembl 8 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 18 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 6 PIR 1 PRO 1 PROSITE 8 PROSITE-ProRule 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 7 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 6 RefSeq 9 Rhea 2 SABIO-RK 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7732023

Title: Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms.

PubMed ID: 7732023

DOI: 10.1073/pnas.92.9.4011

PubMed ID: 12810950

Title: Human acetyl-CoA carboxylase 1 gene: presence of three promoters and heterogeneity at the 5'-untranslated mRNA region.

PubMed ID: 12810950

DOI: 10.1073/pnas.1332670100

PubMed ID: 15333468

Title: Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility.

PubMed ID: 15333468

DOI: 10.1093/carcin/bgh273

PubMed ID: 18487259

Title: Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

PubMed ID: 18487259

DOI: 10.1093/dnares/dsn010

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14643797

Title: Characterisation of an N-terminal variant of acetyl-CoA carboxylase-alpha: expression in human tissues and evolutionary aspects.

PubMed ID: 14643797

DOI: 10.1016/j.bbalip.2003.09.005

PubMed ID: 15607423

Title: Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes.

PubMed ID: 15607423

DOI: 10.1016/j.ygeno.2004.10.001

PubMed ID: 12360400

Title: BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.

PubMed ID: 12360400

DOI: 10.1038/sj.onc.1205915

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16326698

Title: BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.

PubMed ID: 16326698

DOI: 10.1074/jbc.m504652200

PubMed ID: 16698035

Title: ACCA phosphopeptide recognition by the BRCT repeats of BRCA1.

PubMed ID: 16698035

DOI: 10.1016/j.jmb.2006.04.010

PubMed ID: 6114432

Title: Acetyl-CoA carboxylase deficiency: an inborn error of de novo fatty acid synthesis.

PubMed ID: 6114432

DOI: 10.1056/nejm198108203050820

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20457939

Title: Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.

PubMed ID: 20457939

DOI: 10.1073/pnas.1001292107

PubMed ID: 20952656

Title: Crystal structure of Spot 14, a modulator of fatty acid synthesis.

PubMed ID: 20952656

DOI: 10.1073/pnas.1012736107

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 18452305

Title: Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1.

PubMed ID: 18452305

DOI: 10.1021/bi800314m

PubMed ID: 29899443

Title: Structural basis for regulation of human acetyl-CoA carboxylase.

PubMed ID: 29899443

DOI: 10.1038/s41586-018-0201-4

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 2346
  • Mass: 265554
  • Checksum: F1F0A518F8824FFC
  • Sequence:
    • MDEPSPLAQP LELNQHSRFI IGSVSEDNSE DEISNLVKLD LLEEKEGSLS PASVGSDTLS 
DLGISSLQDG LALHIRSSMS GLHLVKQGRD RKKIDSQRDF TVASPAEFVT RFGGNKVIEK 
VLIANNGIAA VKCMRSIRRW SYEMFRNERA IRFVVMVTPE DLKANAEYIK MADHYVPVPG 
GPNNNNYANV ELILDIAKRI PVQAVWAGWG HASENPKLPE LLLKNGIAFM GPPSQAMWAL 
GDKIASSIVA QTAGIPTLPW SGSGLRVDWQ ENDFSKRILN VPQELYEKGY VKDVDDGLQA 
AEEVGYPVMI KASEGGGGKG IRKVNNADDF PNLFRQVQAE VPGSPIFVMR LAKQSRHLEV 
QILADQYGNA ISLFGRDCSV QRRHQKIIEE APATIATPAV FEHMEQCAVK LAKMVGYVSA 
GTVEYLYSQD GSFYFLELNP RLQVEHPCTE MVADVNLPAA QLQIAMGIPL YRIKDIRMMY 
GVSPWGDSPI DFEDSAHVPC PRGHVIAARI TSENPDEGFK PSSGTVQELN FRSNKNVWGY 
FSVAAAGGLH EFADSQFGHC FSWGENREEA ISNMVVALKE LSIRGDFRTT VEYLIKLLET 
ESFQMNRIDT GWLDRLIAEK VQAERPDTML GVVCGALHVA DVSLRNSVSN FLHSLERGQV 
LPAHTLLNTV DVELIYEGVK YVLKVTRQSP NSYVVIMNGS CVEVDVHRLS DGGLLLSYDG 
SSYTTYMKEE VDRYRITIGN KTCVFEKEND PSVMRSPSAG KLIQYIVEDG GHVFAGQCYA 
EIEVMKMVMT LTAVESGCIH YVKRPGAALD PGCVLAKMQL DNPSKVQQAE LHTGSLPRIQ 
STALRGEKLH RVFHYVLDNL VNVMNGYCLP DPFFSSKVKD WVERLMKTLR DPSLPLLELQ 
DIMTSVSGRI PPNVEKSIKK EMAQYASNIT SVLCQFPSQQ IANILDSHAA TLNRKSEREV 
FFMNTQSIVQ LVQRYRSGIR GHMKAVVMDL LRQYLRVETQ FQNGHYDKCV FALREENKSD 
MNTVLNYIFS HAQVTKKNLL VTMLIDQLCG RDPTLTDELL NILTELTQLS KTTNAKVALR 
ARQVLIASHL PSYELRHNQV ESIFLSAIDM YGHQFCIENL QKLILSETSI FDVLPNFFYH 
SNQVVRMAAL EVYVRRAYIA YELNSVQHRQ LKDNTCVVEF QFMLPTSHPN RGNIPTLNRM 
SFSSNLNHYG MTHVASVSDV LLDNSFTPPC QRMGGMVSFR TFEDFVRIFD EVMGCFSDSP 
PQSPTFPEAG HTSLYDEDKV PRDEPIHILN VAIKTDCDIE DDRLAAMFRE FTQQNKATLV 
DHGIRRLTFL VAQKDFRKQV NYEVDRRFHR EFPKFFTFRA RDKFEEDRIY RHLEPALAFQ 
LELNRMRNFD LTAIPCANHK MHLYLGAAKV EVGTEVTDYR FFVRAIIRHS DLVTKEASFE 
YLQNEGERLL LEAMDELEVA FNNTNVRTDC NHIFLNFVPT VIMDPSKIEE SVRSMVMRYG 
SRLWKLRVLQ AELKINIRLT PTGKAIPIRL FLTNESGYYL DISLYKEVTD SRTAQIMFQA 
YGDKQGPLHG MLINTPYVTK DLLQSKRFQA QSLGTTYIYD IPEMFRQSLI KLWESMSTQA 
FLPSPPLPSD MLTYTELVLD DQGQLVHMNR LPGGNEIGMV AWKMTFKSPE YPEGRDIIVI 
GNDITYRIGS FGPQEDLLFL RASELARAEG IPRIYVSANS GARIGLAEEI RHMFHVAWVD 
PEDPYKGYRY LYLTPQDYKR VSALNSVHCE HVEDEGESRY KITDIIGKEE GIGPENLRGS 
GMIAGESSLA YNEIITISLV TCRAIGIGAY LVRLGQRTIQ VENSHLILTG AGALNKVLGR 
EVYTSNNQLG GIQIMHNNGV THCTVCDDFE GVFTVLHWLS YMPKSVHSSV PLLNSKDPID 
RIIEFVPTKT PYDPRWMLAG RPHPTQKGQW LSGFFDYGSF SEIMQPWAQT VVVGRARLGG 
IPVGVVAVET RTVELSIPAD PANLDSEAKI IQQAGQVWFP DSAFKTYQAI KDFNREGLPL 
MVFANWRGFS GGMKDMYDQV LKFGAYIVDG LRECCQPVLV YIPPQAELRG GSWVVIDSSI 
NPRHMEMYAD RESRGSVLEP EGTVEIKFRR KDLVKTMRRV DPVYIHLAER LGTPELSTAE 
RKELENKLKE REEFLIPIYH QVAVQFADLH DTPGRMQEKG VISDILDWKT SRTFFYWRLR 
RLLLEDLVKK KIHNANPELT DGQIQAMLRR WFVEVEGTVK AYVWDNNKDL AEWLEKQLTE 
EDGVHSVIEE NIKCISRDYV LKQIRSLVQA NPEVAMDSII HMTQHISPTQ RAEVIRILST 
MDSPST

Genular Protein ID: 1115952276

Symbol: Q7Z5W8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z5W8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Genevisible 1 GenomeRNAi 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 690
  • Mass: 78272
  • Checksum: 54814516C7A58A06
  • Sequence:
    • IGMVAWKMTF KSPEYPEGRD IIVIGNDITY RIGSFGPQED LLFLRASELA RAEGIPRIYV 
SANSGARIGL AEEIRHMFHV AWVDPEDPYK GYRYLYLTPQ DYKRVSALNS VHCEHVEDEG 
ESRYKITDII GKEEGIGPEN LRGSGMIAGE SSLAYNEIIT ISLVTCRAIG IGAYLVRLGQ 
RTIQVENSHL ILTGAGALNK VLGREVYTSN NQLGGIQIMH NNGVTHCTVC DDFEGVFTVL 
HWLSYMPKSV HSSVPLLNSK DPIDRIIEFV PTKTPYDPRW MLAGRPHPTQ KGQWLSGFFD 
YGSFSEIMQP WAQTVVVGRA RLGGIPVGVV AVETRTVELS IPADPANLDS EAKIIQQAGQ 
VWFPDSAFKT YQAIKDFNRE GLPLMVFANW RGFSGGMKDM YDQVLKFGAY IVDGLRECCQ 
PVLVYIPPQA ELRGGSWVVI DSSINPRHME MYADRESRGS VLEPEGTVEI KFRRKDLVKT 
MRRVDPVYIH LAERLGTPEL STAERKELEN KLKEREEFLI PIYHQVAVQF ADLHDTPGRM 
QEKGVISDIL DWKTSRTFFY WRLRRLLLED LVKKKIHNAN PELTDGQIQA MLRRWFVEVE 
GTVKAYVWDN NKDLAEWLEK QLTEEDGVHS VIEENIKCIS RDYVLKQIRS LVQANPEVAM 
DSIIHMTQHI SPTQRAEVIR ILSTMDSPST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.