Details for: vnd

Gene ID: 31003

Symbol: vnd

Ensembl ID: FBgn0261930

Description: ventral nervous system defective

Associated with

  • Brain development
    (GO:0007420)
  • Cell differentiation
    (GO:0030154)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Dna binding
    (GO:0003677)
  • Glial cell development
    (GO:0021782)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuroblast development
    (GO:0014019)
  • Neuroblast fate determination
    (GO:0007400)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 2054346247

Symbol: VND_DROME

Name: Homeobox protein vnd

UniProtKB Accession Codes:

P22808 Q24589 Q26436 Q9UB43 Q9W5F0

Database IDs:

AGR 1 AlphaFoldDB 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 EMBL 5 EnsemblMetazoa 1 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PDB 7 PDBsum 4 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 7628450

Title: vnd, a gene required for early neurogenesis of Drosophila, encodes a homeodomain protein.

PubMed ID: 7628450

DOI: 10.1002/j.1460-2075.1995.tb07355.x

PubMed ID: 7625694

Title: The NK-2 homeobox gene and the early development of the central nervous system of Drosophila.

PubMed ID: 7625694

DOI: 10.1111/j.1749-6632.1995.tb24830.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731137

Title: From sequence to chromosome: the tip of the X chromosome of D. melanogaster.

PubMed ID: 10731137

DOI: 10.1126/science.287.5461.2220

PubMed ID: 2573058

Title: Drosophila NK-homeobox genes.

PubMed ID: 2573058

DOI: 10.1073/pnas.86.20.7716

PubMed ID: 7643404

Title: The three-dimensional solution structure of the NK-2 homeodomain from Drosophila.

PubMed ID: 7643404

DOI: 10.1006/jmbi.1995.0435

PubMed ID: 9154919

Title: Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.

PubMed ID: 9154919

DOI: 10.1021/bi9620060

Sequence Information:

  • Length: 723
  • Mass: 76422
  • Checksum: 811F20B03A93C95E
  • Sequence:
    • MTTSASLERT PSKRDRDRER DNSSGLGSAG SLPASPQSAI TVSPSSPATP KRPLRTSTPS 
LERKREREDR EDREDRKERQ ERHERDRDHE RFAAVFSTAS TTVPTNTSSS SGLAPEQLRI 
PTGAAAFSGF PGLHSMSSLM LPSSAAVAAA AAAPFLPWSP ILLPPWNHAL LPAAFYPAAL 
RNALPGLFDA KVPSSQRSGF HISDILNLEG SELKNAAAAA AAAAHHGSDL SHHSASESTS 
GHRGQGSHTS PSALSPTPAG VSADEHHNGS GTGGGAGEAD HHSTTEHHAP PSHPQQQHPH 
HQQHHHPHLL LPQQHHQQAV APLPLAHHQS GEAQSHAHAN AAAAHLLASH NAAAAAAVAA 
GQYLPNLPKN FPGSFGDEMS SYHHMAQTML QHSGRSAWIK ENELYGTQQP ASPDSTSPVT 
SEVSYTYIGS NCQTSPALSG DYKSYSRSAD SDALSVGDAL HTLHGSSGNG SAGGAPTAHA 
LHNNNNNTTN NNNHSLKAEG INGAGSGHDD SLNEDGIEED IDDVDDADGS GGGDANGSDG 
LPNKKRKRRV LFTKAQTYEL ERRFRQQRYL SAPEREHLAS LIRLTPTQVK IWFQNHRYKT 
KRAQNEKGYE GHPGLLHGHA THPHHPSALP SPRRVAVPVL VRNGKPCLGD SSKLGADCVS 
VSSATATAMQ NAAAHHLVAL NGAAAYQHAA AAAAGLHAHA HAHAHAHGHG HPHAHAQRAA 
WWP

Genular Protein ID: 4211092854

Symbol: Q0KHX8_DROME

Name: N/A

UniProtKB Accession Codes:

Q0KHX8

Database IDs:

AGR 1 ARBA 4 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 Pfam 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 577
  • Mass: 61398
  • Checksum: E2A24DEE3C8C868D
  • Sequence:
    • MSNYNPNCGY FEDCSYYTNN VFQQDYCMQT DYEYNKHVYD LFDAKVPSSQ RSGFHISDIL 
NLEGSELKNA AAAAAAAAHH GSDLSHHSAS ESTSGHRGQG SHTSPSALSP TPAGVSADEH 
HNGSGTGGGA GEADHHSTTE HHAPPSHPQQ QHPHHQQHHH PHLLLPQQHH QQAVAPLPLA 
HHQSGEAQSH AHANAAAAHL LASHNAAAAA AVAAGQYLPN LPKNFPGSFG DEMSSYHHMA 
QTMLQHSGRS AWIKENELYG TQQPASPDST SPVTSEVSYT YIGSNCQTSP ALSGDYKSYS 
RSADSDALSV GDALHTLHGS SGNGSAGGAP TAHALHNNNN NTTNNNNHSL KAEGINGAGS 
GHDDSLNEDG IEEDIDDVDD ADGSGGGDAN GSDGLPNKKR KRRVLFTKAQ TYELERRFRQ 
QRYLSAPERE HLASLIRLTP TQVKIWFQNH RYKTKRAQNE KGYEGHPGLL HGHATHPHHP 
SALPSPRRVA VPVLVRNGKP CLGDSSKLGA DCVSVSSATA TAMQNAAAHH LVALNGAAAY 
QHAAAAAAGL HAHAHAHAHA HGHGHPHAHA QRAAWWP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.